Mixed Methods Evaluation of a Couples-Based Treatment to Improve CPAP Adherence and Sleep Health Among Patients with Obstructive Sleep Apnea and Increased Risk for Alzheimer's Disease

混合方法评估以夫妻为基础的治疗方法，以改善阻塞性睡眠呼吸暂停和阿尔茨海默病风险增加患者的 CPAP 依从性和睡眠健康

• 批准号: 10339141
• 负责人: Kelly Glazer Baron
• 金额: $ 9.05万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10339141
• 关键词: Address; Adherence; Adult; Affect; Aging; Alzheimer' s Disease; Alzheimer' s disease pathology; Alzheimer' s disease risk; Anxiety; Behavior; Behavioral; Cardiovascular Diseases; Caregivers; Cognition Disorders; Cognitive; Cognitive Therapy; Communication; Continuous Positive Airway Pressure; Couples; Data; Data Collection; Dementia; Development; Disease; Doctor of Philosophy; Effectiveness; Elderly; Evaluation; Evidence based practice; Feedback; Funding; Goals; Hand; Health; Healthcare Systems; Impaired cognition; Intervention; Interview; Knowledge; Link; Literature; Master' s Degree; Mental Depression; Methods; Obstructive Sleep Apnea; Parents; Patient Care; Patient Recruitments; Patients; Process; Public Health; Quality of life; Research; Risk; Role; Sleep; Sleep Disorders; Sleeplessness; Snoring; Structure; Students; Testing; Time; Training; United States National Institutes of Health; acceptability and feasibility; base; cardiometabolism; cardiovascular disorder risk; career development; experience; field study; flexibility; health equity; healthy aging; improved; interest; mild cognitive impairment; mortality; novel; parent grant; poor sleep; preference; pressure; programs; skills; sleep health; sleep quality; theories; therapy development; training opportunity

PROJECT ABSTRACT This diversity supplement is based on the parent grant (R21AG067183) “A novel couples-based sleep health intervention for older adults with obstructive sleep apnea: Implications for Alzheimer’s disease and healthy aging”. In the parent grant, we seek to develop and test a novel couples-based treatment to improve sleep health in patients with obstructive sleep apnea (OSA) and their partners. Through this supplement, we extend the development of our intervention to couples with mild cognitive impairment (MCI) and OSA. The proposed supplement continues and extends the aims of the parent grant by leveraging the existing treatment development processes and recruiting patients from existing trials of the study collaborators. It offers an ideal opportunity for training in conduct of cognitive and sleep assessments, qualitative and quantitative data collection and studies of cognitive disorders. Further, this project will advance the career development of a promising master’s degree student who has aspirations to continue to a PhD program in public health to study aging, health equity and healthcare system factors.

项目摘要 这项多样性补充是基于家长资助(R21AG067183)的一项新的基于夫妻的睡眠健康 老年阻塞性睡眠呼吸暂停的干预：对阿尔茨海默病和健康的影响 老龄化“。在家长资助中，我们寻求开发和测试一种新的以夫妇为基础的治疗方法来改善睡眠 阻塞性睡眠呼吸暂停患者及其伴侣的健康状况。通过这一补充，我们扩展了 我们对患有轻度认知障碍(MCI)和阻塞性睡眠呼吸暂停综合征(OSA)的夫妇进行干预的进展。建议数 通过利用现有的治疗方法，补充补充继续并扩展了父母赠款的目标 开发流程并从研究合作者的现有试验中招募患者。它提供了一种理想的 接受认知和睡眠评估、定性和定量数据培训的机会 认知障碍的收集和研究。此外，该项目将推动一名 有志于继续攻读公共卫生博士学位的有前途的硕士研究生 老龄化、健康公平和医疗保健制度因素。

项目成果

Rationale and study protocol for We-PAP: a randomized pilot/feasibility trial of a couples-based intervention to promote PAP adherence and sleep health compared to an educational control.

• DOI: 10.1186/s40814-022-01089-x
• 发表时间: 2022-08-06
• 期刊: PILOT AND FEASIBILITY STUDIES
• 影响因子: 1.7
• 作者: Baron, Kelly Glazer;Gilles, Allyson;Sundar, Krishna M.;Baucom, Brian R. W.;Duff, Kevin;Troxel, Wendy
• 通讯作者: Troxel, Wendy