Sleep, circadian rhythms: associations with diabetes risk and mood

睡眠、昼夜节律：与糖尿病风险和情绪的关联

• 批准号: 10683676
• 负责人: Kelly Glazer Baron
• 金额: $ 7.97万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-02-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10683676
• 关键词: Affect; American; Area; Beds; Behavioral Mechanisms; Biological; Body fat; Body mass index; Cardiometabolic Disease; Cessation of life; Circadian Rhythms; Circadian desynchrony; Data Analyses; Depressed mood; Desire for food; Development; Diabetes Mellitus; Diet; Doctor of Philosophy; Eligibility Determination; Energy Intake; Environment; Equation; Ethnic Origin; Feeling suicidal; Frequencies; Funding; Glucose; Glycosylated hemoglobin A; Goals; Health; Hormones; Impulsivity; Individual; Insulin Resistance; Intervention; Knowledge; Light; Link; Longitudinal, observational study; Melatonin; Mental Depression; Mental Health; Mentors; Modeling; Mood Disorders; Moods; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Overweight; Pacific Islander; Participant; Pathway interactions; Phase; Positioning Attribute; Postdoctoral Fellow; Process; Public Health; Research; Risk; Risk Factors; Role; Sleep; Suicide; Testing; Training; Universities; Utah; Writing; cardiometabolic risk; cardiometabolism; career; career development; circadian; diabetes risk; disability; disorder risk; doctoral student; experience; experimental study; improved; interest; military service; modifiable risk; neurobehavioral; novel; obesity development; obesity risk; parent grant; premature; programs; public health research; reducing suicide; skills; sleep onset; suicidal risk

ABSTRACT This diversity supplement application is to support the career development of Doreen Egan, MPH, a PhD student in the University of Utah PhD program in Public Health. The parent grant (1R01HL141706-01A1) entitled “Circadian and sleep pathways to cardiometabolic disease risk: role of neurobehavioral processes” is a longitudinal, observational study examining the role of sleep and circadian rhythms in neurobehavioral processes related to obesity (e.g., impulsivity). As described in the candidate plan, Ms. Egan is from an underrepresented ethnic background (Pacific Islander/ Tongan), is a US citizen and is therefore eligible to apply for diversity funds. In addition, Ms. Egan’s application is distinguished by her military service (Army). We are requesting 3 semesters of funding for her career development to support achieving her goal completing her PhD programs in Public Health and preparing for her next step postdoctoral position. Results of this project will support the completion of her dissertation and enhance her skills needed to transition to a postdoctoral position and beyond. The goals of Ms. Egan’s project are to examine sleep and circadian rhythms with suicidal ideation, depression and diabetes risk. The relationships between suicide and diabetes are novel and timely, and the role of sleep and circadian rhythms have not been explored. Ms. Egan will contribute to achieving the aims of the parent grant and complete analyses that will enhance both her training and the findings of the parent grant. The mentoring and training plan will allow Ms. Egan to increase her knowledge of sleep and circadian rhythms, increase skills in data analysis and gain experiences in writing and scientific presentations. Her mentors on the team (Drs. Baron, Jing) are experienced mentors and well-suited to support her professional development in this supplement.

摘要 这种多样性补充申请是为了支持多琳埃根，公共卫生硕士，博士的职业发展 犹他州大学公共卫生博士课程的学生。母公司补助金（1 R 01 HL 141706 - 01 A1） 题为“昼夜节律和睡眠途径对心脏代谢疾病的风险：神经行为过程的作用”是一个 一项纵向观察性研究，检查睡眠和昼夜节律在神经行为中的作用 与肥胖相关的过程（例如，冲动）。正如候选人计划中所描述的，埃根女士来自一个 代表性不足的种族背景（太平洋岛民/汤加人），是美国公民，因此有资格 申请多样性基金。此外，埃根女士的申请以其服过兵役（陆军）为特征。我们 正在申请3个学期的职业发展资金，以支持实现她的目标，完成她的 公共卫生博士课程，并为她的下一步博士后职位做准备。该项目的成果将 支持她完成论文，并提高她过渡到博士后职位所需的技能 以及更远的地方 埃根女士项目的目标是研究睡眠和昼夜节律与自杀意念，抑郁症 和糖尿病风险。自杀和糖尿病之间的关系是新颖和及时的，睡眠的作用 和昼夜节律尚未被探索。埃根女士将有助于实现家长的目标 补助金和完整的分析，这将加强她的培训和家长补助金的调查结果。 指导和培训计划将使埃根女士增加她对睡眠和昼夜节律的了解， 提高数据分析技能，获得写作和科学报告的经验。她的导师们 团队（Baron，Jing博士）是经验丰富的导师，非常适合支持她的专业发展， 这个补充。