NICHD Cooperative Multicenter Neonatal Research Network - (UG1) Ohio State

NICHD 合作多中心新生儿研究网络 - (UG1) 俄亥俄州立大学

• 批准号: 10352222
• 负责人: Pablo J Sanchez
• 金额: $ 27.93万
• 依托单位: RESEARCH INST NATIONWIDE CHILDREN'S HOSP
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10352222
• 关键词: Area; Child; Childhood; Clinical; Clinical Protocols; Clinical Research; Collaborations; Communicable Diseases; Consent; Dedications; Discipline of obstetrics; Disease; Enrollment; Ensure; Evaluation; Follow-Up Studies; Funding; Future; Goals; Gold; Hospitals; Individual; Infant; Infant Care; Infection; Institution; Intervention; Joints; Lead; Leadership; Low Birth Weight Infant; Maternal-Fetal Medicine Units Network; Medical center; Medicine; Methodist Church; Multi-Institutional Clinical Trial; Multi-site clinical study; Multicenter Neonatal Research Network; National Institute of Child Health and Human Development; Neonatal; Neonatology; Newborn Infant; Nurseries; Observational Study; Ohio; Outcome; Patients; Pediatric Hospitals; Performance; Principal Investigator; Protocols documentation; Randomized Clinical Trials; Reapplication; Research; Research Infrastructure; Resources; Role; Safety; Sepsis; Source; Treatment Efficacy; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; Work; antimicrobial; clinical care; clinical center; clinical infrastructure; clinical research site; college; data acquisition; design; early onset; experience; feeding; fetal; follow-up; high risk infant; improved; infant morbidity/mortality; man; member; neonatal care; neonate; pediatric department; perinatal medicine; programs; public health relevance; randomized trial; service delivery; systems research

 DESCRIPTION (provided by applicant): This proposal is a reapplication from the Division of Neonatology at Nationwide Children's Hospital (NCH) and The Ohio State University (OSU) to participate in the multi-center clinical program, the Eunice Kennedy Shriver NICHD Neonatal Research Network (NRN). NCH-OSU has been a member of the NRN since 2011. Pablo Sánchez, MD, Sudarchan Jadcherla, MD, and Nathalie Maitre, MD are the Principal Investigator (PI), Alternate PI, and Follow-up PI, respectively. Dr. Maitre is an important addition to the NRN team. She joins the Neonatology Division at NCH-OSU in July 2015 and has extensive experience in the assessment and follow- up of high risk infants while at Vanderbilt University. Her presence and contribution enhances our follow-up program significantly. As an NRN clinical center, NCH-OSU has the necessary academic, research and clinical infrastructure already in place that will assure continued excellence in the performance of NRN studies. The Neonatology Division at NCH-OSU has demonstrated a strong commitment to clinical research, and in this endeavor, it has the strong support of the OSU Pediatric Department and its clinical facilities, NCH and The Ohio State University Wexner Medical Center where the clinical studies pertaining to this RFA will continue to be performed. Importantly with this submission, a third sit will be added, namely the NCH NICU at Riverside Methodist Hospital (RMH), a facility that boasts the largest inborn delivery service in Columbus. In addition, the Obstetric Dept. of OSU is one of 14 centers of the NICHD Maternal-Fetal Medicine Units (MFMU), and strong collaboration between the OSU MFMU and NCH exists at all levels of clinical care and research. This partnership assures a continued source of diverse patients for clinical studies. NCH-OSU has a proven track record within the NRN, as evidenced by its well organized clinical research program with a high percentage of eligible infants consented for randomized trials and excellence in conducting the studies. The PI has extensive experience in the performance of multicenter, randomized clinical trials. By being board certified in both Neonatology and Pediatric Infectious Diseases, Dr. Sánchez will provide expertise to the NRN on issues in neonatal infectious diseases, a vexing problem among low birth weight infants.