Xavier RCMI Renewal Application-Overall

摘要 保持泽维尔整体研究势头，提升研究能力，再上一个台阶 在关于少数民族健康和健康差距的生物医学研究方面的卓越表现，RCMI癌症研究中心 将实施计划活动以支持早期、任职人数不足的调查人员，维护核心设施 支持各级泽维尔研究人员的职业发展，并促进和维持长期、 泽维尔与当地社区之间的双向伙伴关系，以解决癌症健康差距问题。这个 拟建的RCMI中心将包括两个领域的三个主要研究项目：基础生物医学研究 和行为研究，以及4个核心：管理核心、调查员开发核心、 研究基础设施核心和社区参与核心。这些计划将被实施以 实现以下具体目标：目标1.提高泽维尔在基础生物医学和 行为研究。RCMI计划将维持、加强和优化核心服务，以支持 泽维尔调查员。将对核心设施进行重组、整合，并精简运营，以 最大限度地提高泽维尔正在进行的研究项目的生产率和效率。目标2.支持Xavier调查员 在获得外部资金方面变得更具竞争力。这将通过1)支持两项研究来实现 基础生物医学领域的项目和行为研究领域的一个研究项目 项目绩效指标将在R01应用程序中变得具有竞争力；2)提供关键研究资源，如共享 通过研究基础设施进行竞争性研究项目所需的最先进的仪器 核心；3)通过调查员发展核心提供试点资金，以获得必要的初步资金 用于制定可资助的研究提案的数据；以及4)通过赠款提供资助人培训 写作工作坊和专业的评论服务。目标3.促进泽维尔新员工的职业发展 通过试点项目基金和启动研究/授权“管道”，进行早期调查 支持新教员五年，以获得校外资金。目标4.提高所有科学工作者的素质 通过每半年举办一次的研讨会和 每年举办关于少数群体健康质量和健康差距研究的讲习班，以提供良好的培训 研究人员的科学实践、适当的统计使用和负责任的实验室实践 级别。通过社区参与核心和调查员发展核心，RCMI 该计划将促进基础和行为研究人员、临床医生和 社区利益相关者。目标5.与基于社区的组织建立可持续的关系 将与泽维尔的研究人员合作。将建立社区参与核心，以1)促进和 通过干预策略的双向知识共享维持社区-学术合作伙伴关系 和癌症健康差异的科学发现；2)促进社区更多地参与 研究优先事项，并为学术-从业者-社区研究伙伴关系创造更多机会； 3)在研究人员、社区成员、卫生系统、 和潜在的研究参与者进行创新和变革性的研究，以解决 社区卫生需求；4)为调查人员提供支持，以便更好地向 科学社区、社区组织和非专业社区。

Summary To sustain Xavier’s overall research momentum, enhance research capacity, and advance to the next level of excellence in biomedical research on minority health and health disparities, the RCMI Cancer Research Center will implement program activities to support early stage, underrepresented investigators, maintain core facilities to support Xavier researchers at all levels of career development, and to promote and sustain long-lasting, bidirectional partnerships between Xavier and local communities to address cancer health disparities. The proposed RCMI Center will consist of three major research projects in two areas: basic biomedical research and behavioral research, and 4 Cores: the Administrative Core, the Investigator Development Core, the Research Infrastructure Core, and the Community Engagement Core. These programs will be implemented to achieve the following specific aims: Aim 1. Enhance Xavier’s research capacity for basic biomedical and behavioral research. The RCMI program will maintain, strengthen and optimize core services in support of Xavier investigators. Core facilities will be restructured, consolidated, and operations will be streamlined to maximize productivity and efficiency of Xavier’s ongoing research projects. Aim 2. Enable Xavier investigators to become more competitive in obtaining external funding. This will be achieved by 1) supporting two research projects in the basic biomedical area and one research project in the behavioral research area to enable these project PIs to become competitive in R01 applications; 2) providing critical research resources such as shared state-of-the-art instrumentation required in a competitive research project through the Research Infrastructure Core; 3) providing, through the Investigator Development Core, pilot funding to obtain necessary preliminary data for development of fundable research proposals; and 4) providing grantsmanship training through grant writing workshops and professional review services. Aim 3. Promote career enhancement of Xavier’s new and early stage investigators through a pilot project fund and by initiating a research/grantsmanship “pipeline” supporting new faculty for five years to obtain extramural funding. Aim 4. Enhance the quality of all scientific inquiry and promote research on minority health and health disparities by semi-annual symposiums and workshops on the quality of minority health and health disparities research each year to offer training in good scientific practices, appropriate statistical usage, and responsible laboratory practices for researchers at all levels. Working through the Community Engagement Core and the Investigator Development Core, the RCMI program will foster close interactions and collaborations among basic and behavior researchers, clinicians, and community stakeholders. Aim 5. Establish sustainable relationships with community-based organizations that will partner with Xavier researchers. A Community Engagement Core will be established to 1) promote and sustain community-academic partnerships through bidirectional knowledge sharing on intervention strategies and scientific discovery in cancer health disparities; 2) facilitate greater community involvement in setting research priorities and creating more opportunities for academic-practitioner-community research partnerships; 3) build capacity (knowledge and skills) among research investigators, community members, health systems, and potential research participants to conduct innovative and transformative research that addresses community health needs; 4) provide support for investigators to better disseminate research findings to the scientific community, community organizations, and lay communities.