Pilot Project Program

摘要(试点项目计划) 试点项目计划(PPP)有助于密歇根生命环境中心的使命 (M-LEEAD)，通过支持鼓励创新、创造力和 多学科合作，特别是基础科学家、临床研究人员和社区之间的合作 监管利益相关者。试点项目计划是吸引新的个人到 我们的中心，并提供支持，以产生初步数据，以竞争外部资金。的目标是 试点项目计划是：1)吸引新加入我们中心的资深调查人员，他们可以提供新的 关于生活方式和环境暴露之间关系问题的见解和方法 和疾病；2)鼓励创新、创造力和多学科合作，特别是在基础 科学家、临床研究人员、社区和监管利益相关者；3)促进我们中心成员的 能够快速有效地应对新的快速转变的研究机会，特别是那些 来自NIEHS；以及4)为早期调查人员提供重要支持，以便为 发展自主研究项目，争取自主资金。这种方法是 在前几个资助期取得了成功，从所支持的初级教员人数来看，新的 已经形成的合作，环境健康研究的新手科学家的参与 参加中心活动因试点项目计划、外部赠款的数量 提交的申请、由此产生的出版物数量和职业晋升，所有这些都汇总在 研究策略。过去一年在试点项目方案管理方面取得的重要进展 周期包括：1)与其他P30中心的审查员联盟进一步发展和完善，以 有助于提高审查的客观性，并避免因审查而产生的利益冲突 同一机构的其他人；2)修改后的评分系统和额外的试点资金，以加强社区 参与；以及3)为高度优先领域的探索性工作提供资金的快速反应机制， 周转时间短。在试点项目方案的下一个周期中，我们将在产生的势头的基础上再接再厉 在本供资期间，继续广泛分发申请申请 公共卫生学院和医学院，继续审查联盟并继续促进 使用我们的核心设施。我们还将继续在审查中纳入CEC成员的做法。 负责对提案进行排名以确保其投入的委员会。总而言之，这些做法将继续下去 在试点项目计划的最初周期中开展的开创性研究，以推动 全面和综合的环境健康范式。

ABSTRACT (Pilot Project Program) The Pilot Project Program (PPP) contributes to the mission of the Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) by supporting pilot projects that encourage innovation, creativity, and multidisciplinary collaborations, especially among basic scientists, clinical researchers, and community and regulatory stakeholders. The Pilot Project Program is an important mechanism for attracting new individuals to our Center and for providing support to generate preliminary data to compete for external funding. The aims of the Pilot Project Program are to: 1) attract established investigators new to our Center who can provide new insights and approaches to questions regarding the relationships between lifestage environmental exposures and disease; 2) encourage innovation, creativity, and multidisciplinary collaborations, especially between basic scientists, clinical researchers, and community and regulatory stakeholders; 3) facilitate our Center members' ability to respond quickly and effectively to new and quick-turnaround research opportunities, especially those from NIEHS; and 4) provide important support for early-stage investigators to generate preliminary data for developing independent research projects and compete for independent funding. This approach was successful in the previous funding periods as evidenced by the number of junior faculty supported, the new collaborations that were formed, the participation of scientists new to environmental health research that participated in Center activities as a result of the Pilot Project Program, the number of external grant applications submitted, the number of resulting publications, and career advancement, all as summarized in the Research Strategy. Important advances in the administration of the Pilot Project Program during the last cycle include: 1) the further advancement and refinement of a reviewer consortium with other P30 centers to help improve objectivity of the reviews as well as avoid conflicts of interest that can result from reviews by others in the same institution; 2) a modified scoring system and additional pilot funds to enhance community engagement; and 3) a rapid response mechanism for funding exploratory work in high priority areas with a very short turnaround time. In the next cycle of the Pilot Project Program, we will build on the momentum generated in the current funding period by continuing the wide distribution of the Request for Applications throughout the School of Public Health and the Medical School, continuing the reviewer consortium and continuing to promote the use of our Core facilities. We will also continue our practice of including a CEC member on the review committee responsible for ranking of the proposals to assure their input. Together, these practices will continue the groundbreaking research developed in the initial cycles of the Pilot Project Program to advance a comprehensive and integrated environmental health paradigm.