Using electrical nerve stimulation to control atrial fibrillation
Using electrical nerve stimulation to control atrial fibrillation
批准号:
10397354
负责人:
PENG-SHENG CHEN
金额:
$93.73万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-07-01 至 2024-06-30
中文摘要
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英文摘要
Study Plan: Using electrical nerve stimulation to control atrial fibrillation
Aim 1 will test the hypothesis that subcutaneous (Aim 1A) and transcutaneous (Aim 1B)
electrical nerve stimulation are effective in reducing the frequencies of paroxysmal atrial
fibrillation (AF) and the ventricular rate in patients with severe symptomatic AF unresponsive to
conventional therapies.
Aim 2 will test the hypothesis that in healthy subjects, electroacupuncture or TENS at LI-4 and
LI-11 can acutely activate or suppress skin sympathetic nerve activity (SKNA). We further
hypothesize that chronic TENS will reduce sympathetic output in humans. If confirmed,
repeated TENS may be used in the future clinical trials to control AF.
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Neural Remodeling After Myocardial Infarction: The Importance of Heterogeneity.
心肌梗死后的神经重塑:异质性的重要性。
DOI:
10.1016/j.jacep.2023.05.027
发表时间:
2023
期刊:
JACC. Clinical electrophysiology
影响因子:
--
作者:
[Chen,Peng-Sheng, Fishbein,MichaelC]
通讯作者:
Fishbein,MichaelC
Sympathetic toggled sinus rate acceleration as a mechanism of sustained sinus tachycardia in chronic orthostatic intolerance syndrome.
交感神经窦性心率加速是慢性直立不耐受综合征持续窦性心动过速的机制。
DOI:
10.1016/j.hrthm.2022.08.015
发表时间:
2022
期刊:
Heart rhythm
影响因子:
5.5
作者:
[Hwang,Daerin, Liu,Xiao, Rosenberg,Carine, Lee,Andrew, Borle,Sanjana, Ricafrente,JoselynQ, Wei,Janet, Shufelt,Chrisandra, Chen,LanS, Li,Xiaochun, Goldhaber,JoshuaI, BaireyMerz,CNoel, Chen,Peng-Sheng]
通讯作者:
Chen,Peng-Sheng
The regulation of the small-conductance calcium-activated potassium current and the mechanisms of sex dimorphism in J wave syndrome.
J波综合征小电导钙激活钾电流的调节及性别二态性机制
DOI:
10.1007/s00424-020-02500-3
发表时间:
2021-03
期刊:
Pflugers Archiv : European journal of physiology
影响因子:
--
作者:
[Chen M, Fei Y, Chen TZ, Li YG, Chen PS]
通讯作者:
Chen PS
DOI:
10.1016/j.hrthm.2020.07.036
发表时间:
2021-01
期刊:
Heart rhythm
影响因子:
5.5
作者:
[Fei YD, Chen M, Guo S, Ueoka A, Chen Z, Rubart-von der Lohe M, Everett TH 4th, Qu Z, Weiss JN, Chen PS]
通讯作者:
Chen PS
Deep learning evaluation of echocardiograms to identify occult atrial fibrillation.
超声心动图的深度学习评估以识别隐匿性心房颤动。
DOI:
10.1038/s41746-024-01090-z
发表时间:
2024
期刊:
NPJ digital medicine
影响因子:
15.2
作者:
[Yuan,Neal, Stein,NathanR, Duffy,Grant, Sandhu,RoopinderK, Chugh,SumeetS, Chen,Peng-Sheng, Rosenberg,Carine, Albert,ChristineM, Cheng,Susan, Siegel,RobertJ, Ouyang,David]
通讯作者:
Ouyang,David
共 10 条
Using electrical nerve stimulation to control atrial fibrillation.
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批准号:9807603
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项目类别:
-
资助金额:$70.43万
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财政年份:2019
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负责人:PENG-SHENG CHEN
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依托单位:
SK current and ventricular arrhythmias.
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批准号:10164095
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项目类别:
-
资助金额:$56.18万
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财政年份:2017
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负责人:PENG-SHENG CHEN
-
依托单位:
Subcutaneous nerve stimulation for arrhythmia control.
-
批准号:9405146
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项目类别:
-
资助金额:$67.65万
-
财政年份:2017
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负责人:PENG-SHENG CHEN
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依托单位:
SK Current, beta-3 adrenoceptor activation and Sex Differences in Ventricular Arrhythmogenesis
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批准号:10734708
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项目类别:
-
资助金额:$59.43万
-
财政年份:2017
-
负责人:PENG-SHENG CHEN
-
依托单位:
Autonomic Nerve Activity and Paroxysmal Atrial Fibrillation
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批准号:7822294
-
项目类别:
-
资助金额:$1.79万
-
财政年份:2009
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负责人:PENG-SHENG CHEN
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依托单位:
WAVE DYNAMICS IN NORMAL AND DISEASED RABBIT HEARTS
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批准号:7108467
-
项目类别:
-
资助金额:$35.9万
-
财政年份:2005
-
负责人:PENG-SHENG CHEN
-
依托单位:
Fibrillation and Defibrillation
-
批准号:7171857
-
项目类别:
-
资助金额:$35.91万
-
财政年份:2005
-
负责人:PENG-SHENG CHEN
-
依托单位:
Fibrillation and Defibrillation
-
批准号:7500776
-
项目类别:
-
资助金额:$35.91万
-
财政年份:2005
-
负责人:PENG-SHENG CHEN
-
依托单位:
Fibrillation and Defibrillation
-
批准号:7741761
-
项目类别:
-
资助金额:$38.5万
-
财政年份:2005
-
负责人:PENG-SHENG CHEN
-
依托单位:
Fibrillation and Defibrillation
-
批准号:7012199
-
项目类别:
-
资助金额:$38.08万
-
财政年份:2005
-
负责人:PENG-SHENG CHEN
-
依托单位:
Fibrillation and Defibrillation
-
批准号:7923953
-
项目类别:
-
资助金额:$38.26万
-
财政年份:2005
-
负责人:PENG-SHENG CHEN
-
依托单位:
Fibrillation and Defibrillation
-
批准号:6849511
-
项目类别:
-
资助金额:$39.0万
-
财政年份:2005
-
负责人:PENG-SHENG CHEN
-
依托单位:
Thoracic Veins and Sustained Atrial Fibrillation
-
批准号:6637740
-
项目类别:
-
资助金额:$36.08万
-
财政年份:2002
-
负责人:PENG-SHENG CHEN
-
依托单位:
Thoracic Veins and Sustained Atrial Fibrillation
-
批准号:6531379
-
项目类别:
-
资助金额:$37.4万
-
财政年份:2002
-
负责人:PENG-SHENG CHEN
-
依托单位:
REENTRANT WAVEFRONTS IN VENTRICULAR FIBRILLATION
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批准号:6564938
-
项目类别:
-
资助金额:$23.8万
-
财政年份:2002
-
负责人:PENG-SHENG CHEN
-
依托单位:
Autonomic Nerve Activity and Paroxysmal Atrial Fibrillation
-
批准号:7492935
-
项目类别:
-
资助金额:$37.75万
-
财政年份:2002
-
负责人:PENG-SHENG CHEN
-
依托单位:
Thoracic Veins and Sustained Atrial Fibrillation
-
批准号:6921915
-
项目类别:
-
资助金额:$36.08万
-
财政年份:2002
-
负责人:PENG-SHENG CHEN
-
依托单位:
Autonomic Nerve Activity and Paroxysmal Atrial Fibrillation
-
批准号:7921900
-
项目类别:
-
资助金额:$7.92万
-
财政年份:2002
-
负责人:PENG-SHENG CHEN
-
依托单位:
Autonomic Nerve Activity and Paroxysmal Atrial Fibrillation
-
批准号:8193778
-
项目类别:
-
资助金额:$38.5万
-
财政年份:2002
-
负责人:PENG-SHENG CHEN
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依托单位:
Thoracic Veins and Sustained Atrial Fibrillation
-
批准号:6787644
-
项目类别:
-
资助金额:$36.08万
-
财政年份:2002
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负责人:PENG-SHENG CHEN
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依托单位:
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脊髓电刺激活化Na(V)1.1阳性GABA神经元持续缓解癌痛
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批准号:82371223
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:闻大翔
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依托单位:
基于电阻层析成象和电磁流量计融合的两相流检测研究
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批准号:60772044
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项目类别:面上项目
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资助金额:8.0万元
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批准年份:2007
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负责人:邓湘
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依托单位: