UC Davis Environmental Health Sciences Core Center

摘要 拉丁美洲人不成比例地遭受COVID-19的影响。在加州，拉美裔占总人口的39 但46%的死亡和超过一半的病例。农业雇员是必不可少的工人， SARS-CoV-2的传播率很高，因为社交距离和掩蔽很困难，特别是在非常炎热的地区。 天气此外，SARS-CoV-2在家庭内传播的风险高达农业人口的三分之一。 雇员居住在拥挤的多户住房中（>1人/室）。在这些家庭中，自我隔离或 如果有家庭成员受到感染，隔离是根本不可行的。非药物干预 如检测、社交距离、隔离和隔离等，在减轻艾滋病的影响方面发挥了关键作用。 新冠肺炎。然而，尽管感染风险增加，但拉丁美洲人的检测率较低， 白人和拉丁美洲人更有可能在测试时呈阳性，并且在测试时需要更高水平的护理。 阳性试验在美国，近13%的西班牙裔或拉丁美洲人至少接受过一次注射，10%的人接受过一次注射。 尽管2021年4月19日对所有人开放接种资格，但已完全接种疫苗。 在服务不足和/或脆弱的拉丁裔人口中。我们建议采取三个层次的方法来解决 在加州、约洛、弗雷斯诺、马德拉等以拉丁裔为主的县，COVID-19疫苗接种存在障碍 斯坦尼斯劳斯2019冠状病毒病！提出了克服动机和后勤障碍，以测试， 减少从出现症状到寻求检测、确保检测、收到检测结果、咨询 提高自我隔离、隔离成功率。的 本研究的目的是：（1）减少疫苗犹豫，改善疫苗更新，同时继续促进 通过文化和语言上适当的有针对性的沟通和激励措施进行测试， 社区伙伴，（2）制定扫盲支持的决策过程，以减少疫苗犹豫， 改进疫苗更新，同时继续促进测试，以及（3）评估干预措施对 疫苗犹豫、疫苗接种和测试，通过强大的统计和数学模型， 一个灵活的框架，以评估疫苗推广的不同情况。拟议的研究将利用强大的 社区伙伴关系，与当地CEAL成员合作者的专业知识， 资源，这将加强我们的干预措施的实施，强大的团队组织，调查 发展专门知识，翻译对交流和传播至关重要的材料， 数据捕获、协调、统计和建模支持、评估单元和测试数据， 与疫苗接种工作相结合，以便全面描述和评价 疫苗犹豫和吸收。拉丁美洲农民工人的疫苗优先次序和定期检测机会 经历结构性障碍的社区，如过度拥挤的住房和具有强烈的文化价值观 支持大型扩展设施对于减轻COVID-19相关负担至关重要。

ABSTRACT Latinos have disproportionately suffered from COVID-19. In California, Latinos make up 39% of the population but 46% of deaths and more than half of all cases. Agricultural employees are essential workers and the risk of SARS-CoV-2 transmission is high because social distancing and masking are difficult—especially in very hot weather. In addition, the risk of SARS-CoV-2 transmission within households is high as one-third of agricultural employees live in crowded and multi-family housing (>1 persons/room). In these households, self-isolation or quarantine is simply not feasible when a family member has been exposed. Non-pharmaceutical interventions such as testing, social distancing, quarantine, and isolation have played a critical role in mitigating the impact of COVID-19. However, despite being at increased risk of infection, testing rates among Latinos is lower compared to Whites and Latinos are more likely to be positive when tested and to require higher level of care at the time of positive test. In the US, nearly 13% of Hispanic or Latino have received at least one dose, and 10% have been fully vaccinated, despite eligibility open to all on April 19th, 2021.There is a major gap in COVID-19 vaccination among underserved and/or vulnerable Latino population. We propose a three-tiered approach to address barriers to COVID-19 vaccination in predominantly Latino counties in California, Yolo, Fresno, Madera, and Stanislaus. ÓRALE COVID-19! was proposed to overcome motivational and logistic barriers to testing by decreasing the time from symptoms, to seeking testing, to securing testing, to receiving test results, to consult about self-isolation, quarantine, and increase the proportion who successfully self-isolated and quarantine. The aims of this study are to: (1) reduce vaccine hesitancy, improve vaccine update while continuing to promote testing with culturally and linguistically appropriate targeted communication and incentives guided by trusted community partners, (2) Develop a literacy-supported decision making process to reduce vaccine hesitancy, improve vaccine update while continuing to promote testing, and (3) evaluate the impact of interventions on vaccine hesitancy, uptake of vaccine and testing through robust statistical and mathematical models that provide a flexible framework to evaluate different scenarios of vaccine rollout. The proposed study will leverage strong community partnerships, expertise of collaborators with local CEAL member to incorporate CEAL-developed resources that will strengthen the implementation of our interventions, strong team organization, survey development expertise, translation of materials that will be critical for communication and dissemination, robust data capturing, harmonization, statistical, and modeling support, evaluation unit, and testing data that can be integrated to vaccination efforts to allow for a comprehensive characterization and evaluation of interventions on vaccine hesitancy and uptake. Vaccine prioritization and access to regular testing to Latino farmer worker communities that experience structural barriers such as overcrowded housing and have strong cultural values on support of large extended facilities is critical to reduce the burden associated with COVID-19.