ORALE COVID-19!: Organizaciones para Reducir, Avanzar y Lograr Equidad contra el COVID-19 (Organizations to Reduce, and to Advance, and Lead for Equity against COVID-19)

ORALE COVID-19！：Organizaciones para Reducir、Avanzar y Lograr Equidad contra el COVID-19（针对 COVID-19 减少、推进和领导公平的组织）

• 批准号: 10589332
• 负责人: Irva Hertz-Picciotto
• 金额: $ 124.96万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-05-05 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10589332
• 关键词: Academia; Achievement; Address; Adopted; Advisory Committees; Affect; Air; Air Pollution; Animals; Area; Asthma; Biochemical; Biological; Biological Assay; Biological Markers; Biological Models; Biological Sciences; Biometry; COVID-19; California; Cell Culture Techniques; Chemicals; Collaborations; Communities; Community Actions; Community Developments; Complex; Country; Devices; Diabetes Mellitus; Dimensions; Disease; Dose; Endocrine system; Engineering; Ensure; Environment; Environmental Exposure; Environmental Health; Environmental Impact; Environmental Pollution; Environmental Science; Epidemiology; Faculty; Fostering; Functional disorder; Funding; Generations; Genetic; Genomics; Geography; Health; Health Professional; Health Sciences; Home; Human; Immune; Immune system; In Vitro; Individual; Infrastructure; Integrative Medicine; Interdisciplinary Study; International; Intervention; Knowledge; Lead; Leadership; Learning; Link; Malignant Neoplasms; Measurement; Medicine; Metabolic; Methods; Minority Women; Mission; Modeling; Molecular; Molecular Target; Monitor; National Institute of Environmental Health Sciences; Nervous system structure; Neurodevelopmental Disorder; Outcome; Pathway interactions; Patients; Physiological; Pilot Projects; Policies; Policy Maker; Population; Predisposition; Process; Public Health; Public Health Practice; Pump; Radar; Reproductive system; Research; Research Personnel; Resources; Respiratory System; Risk; Schools; Science; Scientist; Severities; Social Conditions; Social Justice; Strategic Planning; Strategic vision; Stress; Target Populations; Technology; Testing; Time; Toxic effect; Toxicokinetics; Training; Translating; Translational Research; Translations; Underrepresented Minority; Veterinary Medicine; Wildfire; Work; acceptability and feasibility; behavior influence; career; climate-related health; clinical care; college; community engagement; design; disability; environmental justice; epidemiology study; epigenomics; experimental study; exposed human population; exposure route; health equity; health science research; improved; in silico; interdisciplinary approach; interdisciplinary collaboration; interest; member; metabolomics; new technology; novel; nutrition; portability; prevent; programs; prototype; recruit; resilience; respiratory; response; sensor; social media; success; technology development; transcriptomics; translational approach; translational framework; working group

PROJECT SUMMARY - Overall The mission of the UC Davis Environmental Health Sciences Center (EHSC) is to advance understanding of environmentally induced disease and disability and to translate this knowledge into interventions, new practices or policy changes that reduce those exposures or mitigate their effects on health. The EHSC brings together faculty from seven schools and colleges engaged in environmental health sciences (EHS) research spanning molecular biosciences, environmental science, engineering, pathophysiology, biostatistics, epidemiology, and community development, with relevance to human conditions. The EHSC has made huge strides in less than 4 years. Among its notable achievements, the EHSC has: broken through silos, transformed interdisciplinary collaboration into the standard modus operandi among our members, attracted both new and established investigators, and placed environmental health on the radar of other Centers throughout UC Davis. Increasingly, EHSC members are engaging with community stakeholders and seeking to address community-driven questions. A few highlights of EHSC accomplishments are: 1) a novel vivarium facility for air pollution health studies using real-time air pumped from a heavily trafficked tunnel; 2) a program of research on exposures and health effects in response to hugely destructive wildfires now commonplace throughout the western U.S.; 3) recruitment of many new investigators, including two underrepresented minority women; establishment of a strong presence on social media. Guided by the NIEHS 2018-2023 Strategic Plan and the NIEHS Translational Research Framework, we adopted three overarching theme areas: 1) interdisciplinary translational EHS linking molecular/cell culture experiments, whole animal assays, human epidemiologic research, interventions, and policy; 2) integration of environment, social justice and health to understand vulnerability and resilience; 3) building bridges with communities, clinicians, and policy- makers. Layered on those broad themes, we continue to cultivate the historic UCD strengths in research on respiratory, nervous, immune, metabolic, endocrine, and reproductive systems, and recently expanded into cancer and climate-related health research. The Center has a Pilot Projects Program and four cores: Administration, Integrative Health Sciences, Exposure Sciences and Community Engagement, as well as various advisory committees. In the coming funding period, the UC Davis EHSC will expand its scope and impact by 1) advancing cutting-edge research in exposure characterization, environmental health effects, their molecular biologic mechanisms, and technology development for improving measurement of exposures and biomarkers; 2) enlarging the cadre of EHS researchers, and 3) engaging with policy-makers, community stakeholders and health professionals, to ensure relevance of our research and to translate findings into public health improvement. The Center emphasizes inter-disciplinary and translational approaches to environmental health issues and is developing partnerships with other Centers throughout UC Davis.

项目摘要 - 总体 加州大学戴维斯分校环境健康科学中心（EHSC）的任务是提高对 环境引起的疾病和残疾，将这些知识转化为干预措施，新的 实践或政策变化，减少这些暴露或减轻其对健康的影响。 EHSC带来了 来自从事环境健康科学（EHS）研究的七所学校和大学的教师 跨越分子生物科学，环境科学，工程，病理生理学，生物统计学， 流行病学和社区发展与人类状况有关。 EHSC变得巨大 不到4年的进步。在其显着的成就中，EHSC有：隔离筒仓， 在我们的成员中，将跨学科的合作转变为标准的作案手法，吸引了 新的和成熟的调查人员，并将环境卫生放在其他中心的雷达上 整个UC戴维斯。 EHSC成员越来越多地与社区利益相关者互动，并寻求 解决社区驱动的问题。 EHSC成就的一些亮点是：1）新型Vivarium 用于空气污染健康研究的设施，利用从贩运大量隧道中抽出的实时空气； 2）程序 关于响应巨大破坏性野火的暴露和健康影响的研究 整个美国西部； 3）招募许多新调查人员，包括两个代表性不足 少数民族妇女；在社交媒体上建立强大的存在。在NIEHS 2018-2023的指导下 战略计划和NIEHS翻译研究框架，我们采用了三个总体主题 区域：1）跨学科的翻译EHS连接分子/细胞培养实验，全动物测定， 人类流行病学研究，干预和政策； 2）环境的整合，社会正义和 了解脆弱性和韧性； 3）与社区，临床医生和政策 - 建造桥梁 - 制造商。在这些广泛的主题上，我们继续在研究中培养历史性的UCD优势 呼吸道，神经，免疫，代谢，内分泌和生殖系统，最近扩展到 癌症和与气候有关的健康研究。该中心有一个试点项目计划和四个核心： 行政，综合健康科学，曝光科学和社区参与以及 各种咨询委员会。在未来的资金期间，加州大学戴维斯分校EHSC将扩大其范围， 影响1）在暴露表征，环境健康效应和其 分子生物学机制和技术开发，用于改善暴露量的测量 生物标志物； 2）扩大EHS研究人员的干部，3）与政策制定者，社区互动 利益相关者和卫生专业人员，以确保我们的研究相关性并将发现转化为公众 健康改善。该中心强调环境的跨学科和翻译方法 健康问题，并正在与加州大学戴维斯分校的其他中心建立合作伙伴关系。