UC Davis Environmental Health Sciences Core Center

加州大学戴维斯分校环境健康科学核心中心

基本信息

批准号：
9563462
负责人：
Irva Hertz-Picciotto
金额：
$ 7.85万
依托单位：
UNIVERSITY OF CALIFORNIA AT DAVIS
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-05-05 至 2020-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9563462
关键词：
Address Advisory Committees Affect Agriculture Air Pollutants Animals Area Behavior Biochemical Biological Markers Biological Models California Collaborations Communities Community Outreach Complex Computer Simulation Development Devices Dimensions Disease Dose Ecology Endocrine Engineering Ensure Environment Environmental Exposure Environmental Health Environmental Impact Environmental Risk Factor Epidemiology Faculty Food Fostering Functional disorder Funding Generations Genomics Geography Goals Growth Health Health Professional Health Sciences Household Human Human body Immune In Vitro Individual Intake Integrative Medicine International Intervention Knowledge Lead Leadership Measurement Medicine Metabolic Methods Modeling Molecular Molecular Target Nature Nervous system structure Organism Outcome Physiological Pilot Projects Play Policies Policy Maker Population Positioning Attribute Poverty Predisposition Process Program Development Public Health Regulation Research Research Infrastructure Research Personnel Resources Role Schools Science Social Conditions Stress Stretching System Techniques Technology Tissues Toxic effect Toxicokinetics Training Translating Translational Research Translations Universities Veterinary Medicine Veterinary Schools Work advocacy organizations body system career development college disability dissemination research drinking water empowerment epigenomics exposed human population exposure pathway exposure route gene environment interaction hazard immune function improved in vivo innovation interdisciplinary approach interdisciplinary collaboration interest invention learning community literacy medical schools metabolomics new technology novel nutrition organic contaminant organizational structure particle personal care products programs public health relevance research data dissemination respiratory respiratory health skills transcriptomics

项目摘要

DESCRIPTION (provided by applicant) The central theme of the University of California Davis Center "Environmental Exposures, Mechanisms, and the Development of Disease" is the identification of exposure pathways and disease mechanisms in order to deepen understanding of how environmental exposures threaten human health and to develop strategies to mitigate their effects. This Center brings together faculty from 19 departments in four schools and colleges engaged in environmental health sciences (EHS) research spanning molecular mechanisms, exposure science, pathophysiology, and epidemiology, with relevance to human conditions. The Center will markedly expand UC Davis EHS research at UC Davis by: 1) advancing cutting-edge science, 2) enlarging the cadre of EHS researchers, and 3) engaging with policy-makers, advocacy organizations and health professionals, to ensure relevance of our research and to translate findings into public health improvement. This EHS Core Center will build upon a critical mass of faculty independently funded in EHS, facilitate synergistic collaborations and generate novel scientific breakthroughs unlikely to occur without the opportunities for interaction and integratio this Center will provide. The Center will train young investigators and attract faculty previously not working in EHS who bring their skills and technologies to EHS research. Building on the major EHS strengths, the four primary thematic areas are: environmentally-induced effects on 1) nervous system, 2) respiratory, 3) immune, and 4) endocrine or metabolic function. Exposures of interest include an array of particles and volatile organic contaminant compounds in ambient air, and pollutants in drinking water, in food and from household or personal care products. Center leadership will solicit input from an External Science Advisory Committee, an Internal Executive Advisory Committee, and a Community Stakeholder Advisory Committee. The organizational structure includes an Administrative Core, a Career Development Program, a Pilot Projects Program, an Exposure Core, an Integrative Health Sciences Core, and a Community Outreach and Engagement Core.

描述（由申请人提供）加利福尼亚大学戴维斯大学中心“环境暴露，机制和疾病发展”的中心主题是识别暴露途径和疾病机制，以加深对环境暴露如何威胁人类健康的了解并制定减轻其影响的策略。该中心汇集了从参与环境健康科学的四个学校和学院的19个部门的教职员工（EHS）研究，这些研究涵盖了分子机制，暴露科学，病理生理学和流行病学，与人类状况有关。该中心将在加州大学戴维斯分校的UC Davis EHS研究中明显扩展：1）提高尖端科学，2）增加EHS研究人员的干部，以及3）与政策制定者，倡导组织和卫生专业人员的互动，以确保我们的研究的相关性并将发现转化为公共卫生改善。这个EHS核心中心将建立在独立资助的EHS的大量教师的基础上，促进协同合作，并产生新的科学突破，而没有该中心将提供的互动和综合的机会。该中心将培训年轻的调查员，并吸引以前不从事EHS工作的教师，这些EHS将其技能和技术带入EHS研究。在主要EHS强度的基础上，四个主要主题领域是：对环境诱导的对1）神经系统的影响，2）呼吸道，3）免疫和4）内分泌或代谢功能。感兴趣的暴露包括环境空气中的一系列颗粒和挥发性有机污染物，以及饮用水，食物以及家庭或个人护理产品中的污染物。中心领导将征求外部科学咨询委员会，内部执行咨询委员会和社区利益相关者咨询委员会的意见。组织结构包括行政核心，职业发展计划，试点项目计划，曝光核心，综合健康科学核心以及社区外展和参与核心。