Interdisciplinary Bioengineering Research Training in Diabetes

糖尿病跨学科生物工程研究培训

• 批准号: 10417042
• 负责人: Richard KP Benninger
• 金额: $ 19.02万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10417042
• 关键词: Biomedical Engineering; Diabetes Mellitus; Research Training

PROJECT SUMMARY Diabetes is a global heath epidemic affecting close to 400M people worldwide. Even with rigorous management increased risk for diabetic complications remains. Bioengineering approaches are providing innovate technologies that are increasingly overcoming the current limitations in developing new diagnostics, treatments and cures for diabetes and complications. However there is a shortage of a skilled scientific workforce able to work on these developments. The University of Colorado is uniquely placed to develop an innovative new program to train future scientists with the skills and knowledge to solve existing and future problems in diabetes research and clinical care. This includes world-renowned research and clinical programs in diabetes, particularly type1 diabetes; exceptional engineering research and training programs; and bioengineering research and training that is fully integrated with the Medical campus. To maintain the strong and growing areas of cooperation intersecting bioengineering and diabetes research we propose an innovative new training program: Bioengineering Interdisciplinary Training for Diabetes Research. The primary goals of this program are: 1). To attract high-quality trainees with engineering/quantitative backgrounds; 2). To provide in-depth, multi-disciplinary research training for predoctoral trainees integrating bioengineering and diabetes; and 3). To prepare trainees for transition to individual fellowships and research careers in academia or industry. To effectively achieve these goals, our research training will follow 3 core principles: a). That a successful bioengineering career requires an intrinsically multi-disciplinary approach, with scientists equipped with skills covering a broad variety of fields; b). That successful training of these scientists will require constant interactions between trainees and cross- disciplinary mentors at all levels of research; and c). That developing such scientists requires an institutional environment with breadth and depth, established interactions between engineering and clinical science, and faculty committed to this training. Our innovative research training program will combine didactic and hands on coursework, lab-based research, clinical experiences and career skills. Research areas will focus on true strengths at the institution in which established interactions between bioengineering and diabetes are present, including designing biomarkers and therapeutic interventions for diabetes and complication, clinical trials, imaging diagnostics for diabetes and complications, biomaterials and cell-based therapies, and artificial pancreas diabetes management. Our current outcomes achieved in bioengineering training, including for under-represented populations; the depth of expertise in diabetes and engineering research; the significant institutional support, and the wide range of facilities available make a compelling argument to develop such a program at the University of Colorado.

项目总结 糖尿病是一种全球性的健康流行病，影响着全球近4亿人。即使是在严格的 管理增加糖尿病并发症的风险仍然存在。生物工程方法正在提供 创新技术，不断克服当前在开发新技术方面的限制 糖尿病和并发症的诊断、治疗和治疗。然而，熟练的人才短缺。 能够致力于这些发展的科学劳动力。科罗拉多大学位于独特的 开发一项创新的新计划，以培养具有解决现有问题的技能和知识的未来科学家 以及糖尿病研究和临床护理的未来问题。这包括世界知名的研究和 糖尿病，特别是1型糖尿病的临床方案；特殊的工程研究和培训 计划；以及与医学院完全整合的生物工程研究和培训。至 在生物工程和糖尿病研究方面保持强大和不断增长的合作领域 提出创新的培训计划：糖尿病的生物工程跨学科培训 研究。该计划的主要目标是：1)。要吸引高素质的实习生 工程/量化背景；2)。提供深入的、多学科的研究培训 结合生物工程和糖尿病的博士前实习生；3)。为学员做好过渡到 学术界或工业界的个人奖学金和研究生涯。为了有效地实现这些目标，我们的 研究培训将遵循三个核心原则：a)。成功的生物工程事业需要 本质上是多学科方法，科学家拥有涵盖广泛领域的技能； b)。这些科学家的成功培训将需要受训者与交叉学科之间的持续互动 所有研究级别的学科导师；以及c)。培养这样的科学家需要一个机构 具有广度和深度的环境，工程学和临床科学之间建立的互动，以及 致力于这一培训的教职员工。我们的创新研究培训计划将教学和动手相结合 在课程、实验室研究、临床经验和职业技能方面。研究领域将集中在TRUE 在生物工程和糖尿病之间已经建立起相互作用的机构的优势是 目前，包括设计生物标记物和糖尿病及其并发症的治疗干预，临床 试验、糖尿病和并发症的成像诊断、生物材料和基于细胞的治疗，以及 人工胰腺糖尿病治疗。我们目前在生物工程培训方面取得的成果， 包括代表不足的人群；糖尿病和工程研究方面的专业知识深度； 重要的机构支持和广泛的可用设施使人信服 在科罗拉多大学开发这样一个项目。