ADMINISTRATIVE CORE

行政核心支持尤尼斯·肯尼迪·施莱弗智力和发展部的使命 贝勒医学院残疾研究中心(BCM IDDRC)发现IDD的原因与 可能，以了解其发病机制，并开发新的诊断和治疗方法 监督和管理整个中心的活动，传播关于 与国际发展研究中心网络中的研究人员和 世界。胡达·佐格比博士担任中心主任已超过25年，大卫博士也加入了这一行列 纳尔逊和罗德尼·萨马科组成行政核心的执行团队。执行团队是 致力于确保BCM IDDRC成为一个最具创新性和效率的中心。的首要目标是 行政核心是通过鼓励和促进地方和地区的缺碘研究活动来加强BCM的IDD研究活动 合作研究努力，开发治疗IDD的疗法，吸引和培训研究人员 通过参与、沟通和交流，加强IDD研究和信息传播方面的劳动力 对利益相关者进行教育。该核心将通过提供战略支持来支持教师对IDD的研究 核心设施，并随着领域的发展开发新的核心服务。所有的研究项目都被提出。 用于管理核心的使用。这一核心有助于使核心服务与中心的总体使命保持一致， 与核心董事一起监督和确保所提供的服务是高质量和具有成本效益的，以及 确保核心服务充分利用BCM的现有资源和机构支持。核心将会 还通过临床翻译核心支持IDD的翻译工作，旨在帮助研究人员 设计和执行人体研究，包括IRB批准，获得生物制品，诊断 针对IDD患者的研究和治疗干预，以及一个多学科标志性研究项目 这将导致临床试验准备就绪，开发对基因剂量改变特异和敏感的生物标记物。在……里面 为了促进和加强合作努力和知识传播，核心建议 参与、交流和教育计划(欧洲经委会)，扩大中心活动的范围 地方、州和国家层面的利益相关者。欧洲经委会将为社区实施最佳做法 建立和扩展现有社区关系的伙伴关系，以确保持续的双向 沟通，告知调查人员和社区每个小组的问题/关注，确保成功 招募和保留研究参与者，并确定未来在这一人群中进行研究的可行性。这个 行政核心认识到广泛合作的重要性，特别是与国际发展研究中心网络和 将继续为所有网络活动做出贡献并与之协作。

The Administrative Core supports the mission of the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at Baylor College of Medicine (BCM IDDRC) to identify as many causes of IDD as possible, to understand their pathogenesis, and to develop novel diagnostic and therapeutic approaches by providing oversight and management of the activities of the entire Center, disseminating information about advancements and coordinating collaborative efforts with researchers in the IDDRC network and around the world. Dr. Huda Zoghbi has served as the Center Director for more than 25 years and is joined by Drs. David Nelson and Rodney Samaco to form the Executive Team of the Administrative Core. The Executive Team is dedicated to ensuring that the BCM IDDRC is a most innovative and efficient Center. The overarching goal of the Administrative Core is to enhance IDD research activities at BCM by encouraging and fostering local and collaborative research efforts, the development of therapies to treat IDD, attracting and training investigators to enhance the workforce in IDD research and disseminating information through engagement, communication and education of stakeholders. This Core will support faculty research into IDD through provision of strategic core facilities and by developing new core services as fields advance. All research projects are proposed for use of the Administrative Core. This Core helps align core services to the overall mission of the Center, works with the Core Directors to monitor and ensure that the services provided are high-quality and cost-effective, and ensures that the Core services capitalize on existing resources and institutional support from BCM. The core will also support translational efforts in IDD through the Clinical Translational Core, designed to assist investigators with designing and carrying out human research including IRB approval, acquisition of biospecimens, diagnostic studies, and therapeutic interventions for people with IDD and a multidisciplinary signature research project that will lead to clinical trial readiness, developing biomarkers specific and sensitive to altered gene dosage. In order to promote and enhance collaborative efforts and dissemination of knowledge, the Core proposes a plan for engagement, communication, and education (ECE), extending the reach of the Center’s activities to stakeholders at the local, state, and national levels. The ECE will implement best practices for community partnerships building on and extending existing community relationships to ensure ongoing bi-directional communication, inform investigators and the community of questions/concerns by each group, ensure successful recruitment and retention of study participants, and determine feasibility of future studies in this population. The Administrative Core recognizes the importance of broad collaborations, especially with the IDDRC network and will continue to contribute to and collaborate with all network activities.