Administrative Core

管理核心 摘要 计划项目资助(PPG)，题为“大肠杆菌和志贺氏菌感染的致病机制” 人类肠样模型“由一个管理核心(核心A)支持，以维持 协调正在进行的研究和财务活动所需的沟通 三所独立的医学院-马里兰大学、约翰·霍普金斯大学和该大学 都参与了这项研究。管理核心由Dr。 行政核心领导人詹姆斯·凯珀，萨拉·伍兹女士担任PPG 管理员。管理核心位于马里兰大学管理学院 微生物学和免疫学系医学。 行政核心的主要关注点是成功实施方案目标 支持一个协调的研究计划，旨在进一步开发和描述 人肠道模型系统用于研究大肠杆菌和志贺氏菌感染的发病机制。这个 行政核心是本项目小组的总体目标不可或缺的一部分，特别是在协同方面 在项目中。研究项目和PPG中的另外两个核心--肠状核心 和免疫学核心，是高度相互关联的，每个都与其他相互作用。这个 管理核心将维护稳定、灵活但集中化的基础设施，以促进和 协调感染性肠道疾病的多学科研究，让专家参与 胃肠生理学、临床胃肠病学、疫苗学、分子和肠道学 微生物学、儿科学和传染病。领导班子和行政支持 事实证明，在第一个支持期间，本文所述的支持非常有效和灵活 这个PPG。

Administrative Core Summary The Program Project Grant (PPG) entitled “Pathogenesis of E. coli and Shigella Infections in Human Enteroid Models” is supported by an Administrative Core (Core A) to maintain the communication needed to coordinate the research and financial activities being conducted in the three separate medical schools - the University of Maryland, Johns Hopkins, and the University of Virginia – that are participating in this research. The Administrative Core is directed by Dr. James Kaper, the Administrative Core Leader, with Ms. Sarah Woods serving as the PPG Administrator. The Administrative Core is located at the University of Maryland School of Medicine in the Department of Microbiology & Immunology. The main focus of the Administrative Core is the successful implementation of the program goals to support a coordinated research program designed to further develop and characterize the human enteroid model system to study the pathogenesis of E. coli and Shigella infections. The Administrative Core is integral to the overall goals of this PPG, particularly regarding synergy among projects. The Research Projects and the other two cores in this PPG, the Enteroid Core and the Immunology Core, are highly inter-related and each interacts with the others. The Administrative Core will maintain a stable, flexible, yet centralized infrastructure to promote and coordinate multi-disciplinary research in infectious enteric diseases involving experts in gastrointestinal physiology, clinical gastroenterology, vaccinology, molecular and enteric microbiology, pediatrics and infectious diseases. The leadership team and administrative support described herein has proven to be very effective and flexible during the first period of support for this PPG.