Administrative Core

行政核心 总结 该计划项目资助（PPG）题为“致病性E。大肠杆菌和志贺氏菌感染 人类肠道模型”由管理核心（核心A）支持，以维护 为协调联合国系统内正在进行的研究和财务活动所需的沟通， 三所独立的医学院--马里兰州大学、约翰霍普金斯大学和 参与这项研究。行政核心由博士领导。 James Kaper，行政核心领导人，Sarah Woods女士担任PPG 管理员行政核心位于马里兰州大学的 微生物学与免疫学系医学。 行政核心的主要重点是成功实现方案目标 支持旨在进一步开发和表征的协调研究计划， 人肠道模型系统，以研究E.大肠杆菌和志贺氏菌感染。的 行政核心是本项目规划总目标的组成部分，特别是在协同作用方面 在项目之间。研究项目和本PPG中的其他两个核心，肠状核心 和免疫学核心，是高度相互关联的，每一个相互作用。的 管理核心将维持一个稳定、灵活但集中的基础设施， 协调多学科的研究，包括专家在传染性肠道疾病， 胃肠生理学、临床胃肠病学、疫苗学、分子和肠道 微生物学、儿科学和传染病。领导团队和行政支持 在第一个支持期内， 这个PPG。

Administrative Core Summary The Program Project Grant (PPG) entitled “Pathogenesis of E. coli and Shigella Infections in Human Enteroid Models” is supported by an Administrative Core (Core A) to maintain the communication needed to coordinate the research and financial activities being conducted in the three separate medical schools - the University of Maryland, Johns Hopkins, and the University of Virginia – that are participating in this research. The Administrative Core is directed by Dr. James Kaper, the Administrative Core Leader, with Ms. Sarah Woods serving as the PPG Administrator. The Administrative Core is located at the University of Maryland School of Medicine in the Department of Microbiology & Immunology. The main focus of the Administrative Core is the successful implementation of the program goals to support a coordinated research program designed to further develop and characterize the human enteroid model system to study the pathogenesis of E. coli and Shigella infections. The Administrative Core is integral to the overall goals of this PPG, particularly regarding synergy among projects. The Research Projects and the other two cores in this PPG, the Enteroid Core and the Immunology Core, are highly inter-related and each interacts with the others. The Administrative Core will maintain a stable, flexible, yet centralized infrastructure to promote and coordinate multi-disciplinary research in infectious enteric diseases involving experts in gastrointestinal physiology, clinical gastroenterology, vaccinology, molecular and enteric microbiology, pediatrics and infectious diseases. The leadership team and administrative support described herein has proven to be very effective and flexible during the first period of support for this PPG.