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Impact of Reduced Cannabis Use on Functional Outcomes

减少大麻使用对功能结果的影响

基本信息

批准号：
10437223
负责人：
JEAN C. BECKHAM
金额：
$ 16.08万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-20 至 2022-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10437223
关键词：
Abstinence Accidents Address African American American Behavior Behavior Therapy Cannabis Chronic Clinical Clinical Trials Data Data Collection Development Discrimination Ecological momentary assessment Epidemiology Exposure to Frequencies Health Illicit Drugs Impulsivity Intervention Laboratories Lead Literature Measures Memory Mental Health Methods Neuropsychology Outcome Outcome Measure Participant Persons Pharmacotherapy Phase Physical activity Prospective Studies Protocols documentation Public Health Race Reporting Research Risk Sampling Self Efficacy Short-Term Memory Sleep Substance Use Disorder Symptoms Techniques Technology Technology Assessment Testing Time Traffic accidents Underrepresented Populations Unemployment United States addiction contingency management craving drugged driving experience functional outcomes health related quality of life illicit drug use marijuana use marijuana use disorder marijuana user mobile computing negative affect non-suicidal self injury novel strategies parent grant parent project perceived stress physical conditioning portability psychological distress racial discrimination sex suicidal

项目摘要

Cannabis Use Disorder (CUD) is associated with a many negative functional outcomes, and unfortunately rates of CUD are increasing in the United States. More than 8 million Americans reported heavy cannabis use in 2013, representing a 59% increase since 2005. Heavy cannabis use (i.e., use on ≥ 40 of last 90 days) is associated with addiction, unemployment, neuropsychological deficits, lower educational attainment, and reduced physical activity. As shown across multiple epidemiologic samples, Black Americans are more likely to misuse cannabis than other racial groups. Heavy cannabis use has increased at an even higher rate among Black Americans. Racial discrimination remains a persistent and significant public health concern, undermining the health of underrepresented groups living in the USA and may be related to inequities in cannabis use and CUD. Racial discrimination is defined as unfair, differential treatment on the basis of race. There is a robust association between the experience of racial discrimination and psychological distress. Current evidence indicate that repeated everyday racial hassles are also associated with psychological distress and physical health. Persons who use cannabis to cope with negative affect are at increased risk of developing CUD. Currently, limited data exist examining the relationship between perceived discrimination and cannabis use outcomes although several recent studies suggest perceived stress and discrimination may be important determinants of cannabis use trajectories. These studies are limited, however, by a reliance on retrospective reports of perceived exposure to discrimination. We propose to supplement our parent project and state-of-the-art ecological momentary assessment (EMA) protocol with multiple measures of perceived discrimination to 1) Evaluate whether exposure to chronic discrimination is related to a) reported cannabis-related problems b) ad lib cannabis use in grams and b) magnitude of cannabis reduction during a four-week intervention period, and 2) Use ecological momentary assessment (EMA) technology to measure the daily association between perceived discrimination and cannabis use. Our central hypothesis for the proposed supplement is that experiences of discrimination and daily perceived unfair treatment will be related to cannabis use outcomes. The rationale for this research is that it will provide the first and only real-time data on this important, but understudied topic. Thus, our findings will directly inform our understanding regarding the effects of past and ongoing racial discrimination on cannabis use and misuse.

大麻使用障碍（CUD）与许多负面的功能结果有关，不幸的是