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Uncovering New Mechanisms of Metabolite-Sensing and Signaling

Uncovering New Mechanisms of Metabolite-Sensing and Signaling
发现代谢物传感和信号传导的新机制
批准号:
DP210102840
负责人:
Dr John Scott
金额:
$33.18万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2023-12-31

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中文摘要
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英文摘要
This project aims to understand how cells sense changes in metabolic activity, to ensure energy demands are matched with nutrient supply. Our proposal will fill critical gaps in our understanding of the molecular mechanisms underlying metabolic sensing. This will generate new knowledge with far reaching potential for Australian industries that rely on the propagation and utilization of living organisms, including agriculture, biotechnology and brewing, as well as knowledge relevant to sporting performance and the metabolic dimensions of ageing. This project will support advanced training of early career researchers and PhD students, which will expand Australian research capabilities and contribute to a producing a highly skilled workforce.
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Regulation of energy metabolism by CaMKK2
  • 批准号:
    nhmrc : GNT1138102
  • 项目类别:
    Project Grants
  • 资助金额:
    $44.91万
  • 财政年份:
    2018
  • 负责人:
    Dr John Scott
  • 依托单位:
Regulation of energy metabolism by CaMKK2
Signaling pathways to enhance potency of AMPK-targeting drugs
Metabolic stress sensing by AMPK: implications for energy balance and isoform-targetting therapeutics
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