Regulation of energy metabolism by CaMKK2

CaMKK2 调节能量代谢

• 批准号: nhmrc : GNT1138102
• 负责人: Dr John Scott
• 金额: $ 44.91万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/regulation-energy-metabolism-camkk2/1348121
• 关键词: Regulation; energy; metabolism; CaMKK2

The dramatic increase in obesity and age-related metabolic disorders demonstrates the importance of gaining a better understanding of how cells and organisms regulate their energy stores. This project will identify novel molecular mechanisms that control the enzyme CaMKK2, which is a key regulator of whole-body energy metabolism. This will provide new opportunities to inform more effective strategies to tackle metabolic diseases, and improve health in an increasingly ageing population.

肥胖和与年龄相关的代谢紊乱的急剧增加表明了更好地了解细胞和生物体如何调节其能量储存的重要性。该项目将确定控制酶CaMKK2的新分子机制，CaMKK2是全身能量代谢的关键调节因子。这将提供新的机会，为应对代谢疾病提供更有效的策略，并改善日益老龄化的人口的健康状况。