The Johns Hopkins Alzheimer's Disease Resource Center for Minority Aging Research - Analysis Core

约翰霍普金斯大学阿尔茨海默氏病资源中心少数民族老龄化研究 - 分析核心

• 批准号: 10451583
• 负责人: Qian-Li Xue
• 金额: $ 11.33万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2023-08-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10451583
• 关键词: Address; Adult; Affect; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Automobile Driving; Baltimore; Behavioral; Biological; Biometry; Cessation of life; Characteristics; Clinical; Collaborations; Communities; Community Healthcare; Complex; Data; Data Analyses; Dementia; Development; Discipline of Nursing; Disease; Early Diagnosis; Economics; Education; Effectiveness; Elderly; Ensure; Environmental Exposure; Epidemiology; Etiology; Face; Family; Family Caregiver; Fostering; Foundations; Genetic; Gerontology; Goals; Health; Health Disparities Research; Health Personnel; Impaired cognition; Individual; Inequality; Infrastructure; Institutes; Institution; Intervention; Intervention Studies; Intramural Research Program; Knowledge; Lead; Leadership; Life Cycle Stages; Longevity; Measures; Mentors; Methodology; Methods; Minority; Minority Groups; Minority Recruitment; Modeling; Modernization; Participant; Pilot Projects; Population Intervention; Positioning Attribute; Preventive; Primary Health Care; Proxy; Public Health; Recording of previous events; Research; Research Design; Research Methodology; Research Personnel; Research Support; Resources; Risk; Schools; Scientist; Social Network; Structure; Technology; Testing; Time; Translating; Treatment Efficacy; Universities; Work; base; career; cognitive function; cohort; community engagement; community organizations; community-level factor; data acquisition; data management; data resource; dementia risk; design; education research; empowered; ethnic minority; faculty support; functional loss; health disparity; medical schools; member; multiple data sources; next generation; prevent; programs; racial and ethnic; recruit; response; role model; skills; social; social structure; temporal measurement; therapy development; tool; web site

The Schools of Medicine, Nursing, and Public Health of the Johns Hopkins University are proposing a new Alzheimer's-related Resources Center for Minority Aging Research (AD- RCMAR) in response to RFA-AG-18-002. The aims of this application are to: (1) mentor early- stage investigators from underrepresented backgrounds in minority aging and health disparities research, with a focus on Alzheimer's disease and related disorders (ADRD), using a life course perspective encompassing biological, behavioral, and community factors contributing to cognitive impairment and dementia in older minority adults; (2) conduct epidemiological, preventive, and intervention research that addresses ADRD in later life within a multi-level framework that encompasses individuals, families, social networks, and communities; and 3) engage communities and health care providers – especially family caregivers, primary care practices, communities of faith, and community organizations – as our partners in recognizing dementia and developing interventions with the potential to prevent cognitive decline and reduce ADRD dementia risk and disparities in minority older adults. The Johns Hopkins AD- RCMAR consists of: (1) an Administrative Core whose function is to provide governance and an administrative structure, to support research, to foster interactions between Cores and other Centers, and to ensure RCMAR Scientists develop mentoring relationships across the affiliated departments, schools, the intramural program at NIA in Baltimore, and nationally; (2) a Research Education Component to foster diverse junior investigators and mid-career investigators transitioning into ADRD-relevant research through support for individual pilot projects, career mentoring, scholar-to-scholar interactions, and role modeling; (3) a Community- Liaison and Recruitment Core to ensure the relevance of the ADRD research and to increase knowledge of engagement of community members in the research enterprise with the creation of a Community Resource Institute as a venue for community-investigator interaction; and (4) an Analysis Core as a foundation for methodological and statistical mentoring, including education and mentoring in mixed-methods research. An Executive Committee includes community representatives and a Scientific Advisory Panel consists of distinguished investigators with relevant expertise in minority aging, disparities, and ADRD. A pilot project program supported by all Cores to facilitate the development of RCMAR Scientists includes three initial pilot projects focusing on recruitment of minority populations for ADRD research, early diagnoses of dementia, and intervention development related to ADRD-related driving disparities.

约翰霍普金斯大学医学院、护理学院和公共卫生学院 建议建立一个新的阿尔茨海默氏症相关资源中心，用于少数民族老龄化研究（AD- RCMAR）响应RFA-AG-18-002。该应用程序的目的是：（1）早期指导- 来自少数民族老龄化和健康差异中代表性不足背景的阶段调查人员 研究，重点是阿尔茨海默病和相关疾病（ADRD），使用生命过程 包括生物，行为和社区因素的观点，有助于 少数民族老年人的认知障碍和痴呆;（2）进行流行病学调查， 预防和干预研究，解决ADRD在以后的生活在一个多层次的 包括个人、家庭、社交网络和社区的框架; 3） 让社区和卫生保健提供者参与进来-特别是家庭照顾者、初级保健 实践，信仰社区和社区组织-作为我们的合作伙伴， 痴呆症和开发有可能预防认知能力下降的干预措施， 减少少数老年人的ADRD痴呆风险和差异。约翰霍普金斯广告- RCMAR包括：（1）一个行政核心，其职能是提供治理， 行政结构，以支持研究，促进核心和其他 中心，并确保RCMAR科学家在附属机构之间建立指导关系 部门，学校，在巴尔的摩NIA的校内计划，和全国;（2）一个 研究教育部分，以培养多样化的初级调查员和职业中期 研究者通过支持个体试点，过渡到ADRD相关研究 项目，职业指导，学生与学者的互动，以及角色塑造;（3）社区- 联络和招聘核心，以确保ADRD研究的相关性，并增加 社区成员参与研究企业的知识， 社区资源研究所作为社区调查人员互动的场所;以及（4） 分析核心作为方法和统计指导的基础，包括教育 和指导混合方法研究。执行委员会包括社区 科学顾问小组由杰出的研究人员组成， 在少数民族老龄化，差距和ADRD的相关专业知识。一个试点项目计划得到支持 由所有核心，以促进RCMAR科学家的发展，包括三个初始试点 项目重点是招募少数民族人口进行ADRD研究， 痴呆症，以及与ADRD相关的驾驶差异相关的干预发展。