Outreach, Recruitment and Engagement Core

项目摘要-外联征聘和参与核心（OREC） 非裔美国人和西班牙裔社区痴呆症患病率的增加加剧了 ADRD在这些历史上代表性不足的群体中造成的不成比例的经济和社会负担， 如果这些趋势继续下去，就会造成公共卫生危机。创新治疗方法， 治疗，我们需要了解AD表型的最广泛特征，以发现 新的生物标志物，指示疾病的疾病分类和阶段。加州大学戴维斯分校是全国少数民族招聘的领导者 和保留，由于其对社区为基础的示范性研究（CBPR）的原则的承诺。 在其近30年的历史，加州大学戴维斯分校ADRC已经制定了强大的推广和招聘流程 可靠地识别，有效地筛选，并明确同意老年人参与者从广泛的， 社会经济地位、教育和文化背景。我们建议加强我们的持续亲自努力， 免费数字电子工具箱。这些电子工具使用新颖的数字媒体营销， 独特的参与者人口统计/兴趣（例如，无认知障碍的非裔美国老年人 独自生活在城市环境中）具有特定内容（例如，一段关于如何应对孤独的视频， 何时去看医生的标志），从而提高参与者的参与度， 有意义的招聘经验。我们将面对面资源和电子资源的组合工具箱称为 令人难忘的外联，招聘，保留和参与（MORRE）工具箱。使用所述增强的 我们的目标是：（1）外展到黑人，西班牙裔和白色不同的老年人社区 北方加州的老年人;（2）.激起有色人种社区的兴趣和行动号召 在一个临床研究计划，重点是阿尔茨海默氏症和相关痴呆症;（3）保留我们的 参与者在这个临床队列的定制制作（a）赞赏活动（在人和数字），重点是 他们个人贡献的时间和努力如何在护理和治疗发现方面产生差异;（B） 易于使用的健康教育媒体环境个性化每个参与者的年龄，教育和 使用熟悉的数字平台（例如，脸书、YouTube、电子通讯， 根据喜欢和观看历史推荐内容）;以及（4）通过我们的 社区咨询委员会（CAB）正在就研究项目设计、社区原则 和优先事项，可能影响招聘的潜在促进者和障碍，并制定基于社区的战略 研究项目实施。这个OREC的重要性在于它对一个 通过与NIA、其他ADRC核心和当地社区的广泛合作，实现CBPR的中心范围愿景 伙伴OREC的科学影响将是它创造的复杂技术资源， 加强招募，评估和保留黑人和西班牙裔进入临床研究。

PROJECT SUMMARY – Outreach Recruitment and Engagement Core (OREC) Increased prevalence of dementia in African American and Hispanic communities compounds the disproportionate economic and social burden that ADRD has in these historically under-represented groups, thereby creating a public health crisis should these trends continue unabated. To innovate cures and treatments, we need to understand the broadest characterization of AD phenotypes to enable discovery for new biomarkers that index disease nosology and stage. UC Davis is a national leader for minority recruitment and retention due to its commitment to the principles of Community-Based Participatory Research (CBPR). Over its nearly 30-year history, the UC Davis ADRC has developed robust outreach and recruitment processes that reliably identifies, efficiently screens, and clearly consents older adult participants from a wide range of SES, educational and cultural backgrounds. We propose to enhance our continuing in-person efforts with a complimentary digital e-toolbox. These e-tools use novel digital media marketing that allows us to match unique participant demographics/interests (e.g., African American older adult without cognitive impairment living alone in an urban setting) with specific content (e.g., a video vignette about coping with loneliness and signs for when to see a doctor), thus enhancing participant engagement and creating a personally meaningful recruitment experience. We refer to the combined toolbox of both in-person and e-resources as the Memorable Outreach, Recruitment, Retention and Engagement (MORRE) toolbox. Using the enhanced MORRE toolbox we aim to: (1) Outreach to diverse older adult communities of Black, Hispanic and White older adults across Northern California; (2). Pique interest and call-to-action communities of color to participate in a clinical research program focusing on Alzheimer’s disease and related dementias; (3) Retain our participants in this clinical cohort by tailor making (a) appreciation events (in-person and digital) to focus on how their personal contributions of time and effort make the difference in care and treatment discovery; (b) easy-to-use health education media environment personalized to each participant’s age, education and level/stage of disability in-person using familiar digital platforms (e.g., Facebook, YouTube, e-newsletters, recommended content based on likes and viewing histories); and (4) Engage community leaders through our community advisory board (CAB) in an ongoing dialogue about research project design, community principles and priorities, potential facilitators and barriers that may impact recruitment, and strategize community-based research project implementation. The significance of this OREC is its foundational support and advocacy for a center-wide vision of CBPR though extensive collaboration with NIA, other ADRC cores and local community partners. The scientific impact of the OREC will be its creation of sophisticated technical resources that enhance recruitment, assessment and retention of Blacks and Hispanics into clinical research studies.