Research Training in Pediatric Urology/CHB T32

项目摘要 这是国家研究服务奖(NRSA)机构的竞争性续签申请 培训补助金(T32)，用于波士顿儿童医院的儿科泌尿外科研究培训。在过去14年中 多年来，这一资助机制一直支持我们的儿科泌尿科奖学金的研究部分 程序。波士顿儿童医院的儿科泌尿科奖学金是历史最悠久、也是最多的 这样的节目在世界上备受推崇。BCH的泌尿科是世界领先的 儿科泌尿外科和泌尿生殖重建中心，拥有最大的研究项目之一 致力于国内的基础泌尿学研究。 培训计划的总体目标是：(1)教授最先进的、受假设驱动的、现代的 与基础科学和临床研究相关的研究方法；(2)提供充足的时间 和指导在基础、翻译或临床研究方面的成熟博士后经验 学员未来的临床职业生涯和学术领导角色；(3)为学员提供有形的技能 科学写作、指导、人事管理和领导力，以促进他们向 作为临床医生-科学家的独立职业；以及(4)通过职业发展和 由调查员发起的拨款。在最近的资助周期中，拥有 已完成泌尿外科住院医师培训，从事以实验室为基础的泌尿生殖道研究 发育、生理学和病理生理学。临床结果和卫生服务研究方面的培训 也可以与哈佛大学公共卫生学院的教职员工一起使用。受训人员也 接受批判性思维和拨款撰写、生物统计学和负责任的行为方面的教学培训 研究。每年需要两个博士后职位，为期两年的研究培训。二十 由7个项目的基础科学和临床教员组成的8名临床讲师将 支持培训计划。 该奖学金代表了杰出的基础、翻译和临床研究的独特组合。 在世界领先的学术医学和生物医学中心之一接受培训。它是 旨在使我们的毕业生能够建立他们自己的有竞争力的学术和研究项目 在他们作为学术儿科泌尿科医生的职业生涯中。我们预计这些临床医生和科学家将成为 通过对泌尿生殖系统的了解，成为泌尿外科学术领域的领军人物 基本术语，将基础研究成果转化为临床应用，并理解 新发现对病人护理的影响。T32儿科泌尿外科科研培训机制 是研究员在其研究金的研究部分期间的主要支助来源。

Project Summary This is a competitive renewal application for a National Research Service Award (NRSA) Institutional Training grant (T32) for research training in pediatric urology at Boston Children's Hospital. For the past 14 years, this funding mechanism has supported the research component of our pediatric urology fellowship program. The pediatric urology fellowship at Boston Children's Hospital is the oldest and one of the most highly regarded such programs in the world. The Urology Department at BCH is one of the world's leading centers for pediatric urology and genitourinary reconstruction and has one of the largest research programs dedicated to basic urology research in the country. The overall goals of the training program are: (1) to teach state-of-the-art, hypothesis-driven, modern research methodology relevant to both basic science and clinical research; (2) to provide sufficient time and guidance for a mature postdoctoral experience in basic, translational or clinical studies relevant to the trainees' future clinical careers and academic leadership roles; (3) to provide trainees' with tangible skills in scientific writing, mentoring, personnel management and leadership to facilitate their transition to independent careers as clinician-scientists; and (4) to facilitate funding through career development and investigator-initiated grants. In the most recent funding cycle, postdoctoral MD trainees who have completed urology residency have conducted research in laboratory-based studies of urogenital tract development, physiology and pathophysiology. Training in clinical outcomes and health services research is also available in conjunction with faculty at the Harvard T.H. Chan School of Public Health. Trainees also undergo didactic training in critical thinking and grant writing, biostatistics and the responsible conduct of research. Two postdoctoral positions are requested per year for 2 years of research training. Twenty preceptors and 8 clinical preceptors comprising basic science and clinical faculty from 7 programs will support the training program. The fellowship represents a unique combination of outstanding basic, translational and clinical research training within one of the world's leading centers for academic medicine and biomedical science. It is designed to enable our graduates to establish their own competitive programs of scholarship and research during their careers as academic pediatric urologists. We anticipate these clinician-scientists will become leaders in academic urology through contributions to understanding the genitourinary system in fundamental terms, to translating basic research findings into clinical applications and to understanding the implications of new discoveries for patient care. The T32 Pediatric Urology Research Training mechanism is the major source of support for the fellows during the research component of their fellowship.