Case Urology Translational Research Training Program (CUTRTP)

泌尿外科案例转化研究培训计划 (CUTRTP)

• 批准号: 8267771
• 负责人: Firouz Daneshgari
• 金额: $ 12.78万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8267771
• 关键词: Research Training; Training Programs; Translational Research; Urology

DESCRIPTION (provided by applicant): Urological diseases which include conditions of the genito-urinary tract (GU) can be congenital or acquired, malignant or benign, and medical or surgical. Roughly more than 25 million visits to physicians and hospitals took place in 2000 for just the top 4 urologic conditions; however, the research portfolio to address them lags. Most experts would consider the shortage of qualified scientists and urologists-scientists as the most important contributing factor. Thus, the Urology Institute of the Case Western Reserve University (CWRU) Medical Center (CWRU UI) was created with the overarching goal of rapid expansion of translational research and training of a new generation of scientists and surgeon-scientists. Through the funding requested in this proposal we propose to establish the CWRU Urology Translational Research Training Program (CUTRTP), to expand our current support for the training of 2 to 6 postdoctoral PhD or postgraduate MDs, per year (12 total over 5-years), in two tracks of scientists (for Ph.D. or M.D. candidates) and surgeon-scientists (for MD Candidates). All candidates must have a strong desire to pursue a career in academic medicine focusing on translational research. The ideal successful PhD candidates will have completed their training and potentially, 0-1 years of postdoctoral work. The ideal successful MD candidates will have received their MD and completed residency in urology, gynecology, or family medicine at an ACGME accredited program, and have a history of research. The CUTRTP is based on 3 training pillars: 1) a translational focus for trainees with basic and clinica mentors to yield greater impact on improved patient care and outcomes 2) recruitment of the top researchers from other fields at CWRU as trainers of future investigators, 3) didactic and professional training, with milestones, evaluated by an independent Evaluation Committee. Using a structured curriculum, we propose to train a group of scientists and surgeon-scientists to focus on translational urology research in 3 main areas: a) genitourinary cancers, b) female pelvic floor disorders, and c) urological complications of obesity and diabetes. All trainees will receive the same level and commitment of mentoring throughout their 2 years of devoted research and must compete for the 2nd year position with other qualified trainees. A group of 29 outstanding trainers from 15 departments with a cumulative NIH-funding total of approximately $30 million have come together in the CUTRTP to ensure selection, recruitment, training, and delivery of some of the best scientists and surgeon-scientists in urological diseases. PUBLIC HEALTH RELEVANCE: Urological diseases may be life-threatening (including kidney and prostate cancers) or cause severe deterioration in quality of life (including urinary incontinence). As the U.S. population ages, these conditions will likely cause an even greater burden to patients and the healthcare system. This proposal would ensure training and development of new highly-qualified scientists and surgeon-scientists to ensure continued research into new treatment strategies for urological diseases using a bench to bedside approach to ultimately improve patient care.

描述（由申请人提供）：包括生殖器疗程条件（GU）的泌尿外科疾病可以是先天性的或获得，恶性或良性的，以及医疗或手术。在2000年，对于泌尿科条件，大约有超过2500万次访问医师和医院。但是，解决他们滞后的研究组合。大多数专家都将合格的科学家和泌尿科医生的短缺视为最重要的因素。因此，案例西部储备大学（CWRU）医学中心（CWRU UI）的泌尿外科研究所的总体目标是快速扩大转化研究和新一代科学家和外科医生科学家的培训。通过本提案中要求的资金，我们建议建立CWRU泌尿外科转化研究培训计划（CUTRTP），以扩大我们目前对2至6次培训的支持，每年为2至6个学术博士学位或研究生MDS（在5年内总共12个），在两种科学家中（用于Ph.D.或M.D.候选人）和M.D.候选人和Sublains-Scyon-Scigistists（用于M.D. Candidates和M.D. candistists）（供M.D. Candidistiss）（供您使用）。所有候选人都必须强烈希望从事专注于转化研究的学术医学职业。理想的成功的博士候选人将完成他们的培训，并有可能在10 - 1年的博士后工作。理想的成功的MD候选人将在ACGME认可的计划中获得其MD并完成泌尿外科，妇科或家庭医学的居留权，并拥有研究史。 CUTRTP基于3个培训支柱：1）具有基础和临床指导者的受训者的转化重点，以对改善患者护理和结果产生更大的影响2）CWRU的其他领域的顶级研究人员作为未来研究人员的其他领域的最高研究人员，3）DIDACTIC和专业培训的培训，并接受了具有里程碑意见的教育委员会，并受到了独立评估委员会的评估。使用结构化课程，我们建议培训一组科学家和外科医生，以专注于3个主要领域的翻译泌尿科研究：a）泌尿生殖器癌，b）雌性骨盆底疾病，以及c）肥胖和糖尿病的泌尿外识并发症。所有学员将在整个两年的专门研究中都获得相同的水平和承诺，并且必须与其他合格的学员争夺第二年的职位。来自15个部门的29名杰出培训师组成的NIH累积总计约3000万美元，在CUTRTP中汇集在一起​​，以确保选择，招募，培训和交付一些最好的科学家和外科医生在泌尿外科疾病中。 公共卫生相关性：泌尿科疾病可能会威胁生命（包括肾脏和前列腺癌），或者导致生活质量严重恶化（包括尿失禁）。随着美国人口的年龄，这些条件可能会给患者和医疗保健系统带来更大的负担。该提案将确保对新的高度合格科学家和外科医生的培训和开发，以确保使用基准式床边方法的泌尿科疾病的新治疗策略继续研究，以最终改善患者护理。