NIDCD National Temporal Bone Hearing and Balance Pathology Resource Registry

项目摘要 一项全面的计划被提出，以促进人类颞骨的招募 捐赠者，2)获得捐赠标本并将其分发给活跃的实验室，3)开发 以及维护可搜索的未识别数据库，包括诊断、组织病理学 摘要、听力数据和成套数字化图像，4)经纪特别节目 使用人类耳科材料的研究人员的需求，以及5)教育努力 包括面向公众和感兴趣的专业人士的教育推广活动，包括科学家和 器官采购专家和承办人。就像过去26年来的情况一样，这 将通过维护和加强协调的时间 骨骼登记处。拟议的登记处职能将由菲利佩·桑托斯医学博士监督。 (首席调查员)由艾丽西亚·奎斯奈尔(医学博士)(联合印联调查员)和 M.Charles Liberman，博士(联合首席调查员)。将从以下位置征求其他意见 其他在促进人权方面有经验和专业兴趣的部门成员 颞骨组织病理学，包括D.Bradley Wling，M.D.，Ph.D.和Joseph B.Nadol， 医学博士。 书记官处的NIDCD方案协调员将提供额外的监督 将帮助选择一个指导委员会，包括书记官处、项目 协调员和2至3名外部科学家，了解和欣赏 耳病理学和基础耳科学研究。

Project Summary A comprehensive program is proposed to facilitate 1) recruitment of human temporal bone donors, 2) accrual and distribution of donated specimens to active laboratories, 3) development and maintenance of searchable de-identified databases including diagnoses, histopathological summaries, audiometric data and complete sets of digitized images, 4) brokering of special needs of research investigators using human otologic material, and 5) educational efforts including educational outreach to the public and interested professionals including scientists and organ procurement specialists and undertakers. As has been the case for the last 26 years, this will be accomplished through the maintenance and enhancement of a coordinated Temporal Bone Registry Office. The proposed Registry function will be overseen by Felipe Santos, M.D. (Principal Investigator) with assistance from Alicia Quesnel, M.D. (Co-Prinicpal Investigator) and M. Charles Liberman, Ph.D. (Co- Principal Investigator). Additional input will be solicited from other Departmental members with experience and professional interest in furtherance of human temporal bone histopathology, including D. Bradley Welling, M.D., Ph.D and Joseph B. Nadol, M.D. Additional oversight will be provided by the NIDCD Program Coordinator for the Registry who will help in the selection of a Steering Committee including the PI of the Registry, the Project Coordinator and 2 to 3 external scientists with an understanding and appreciation of the value of otopathology and basic otologic research.