PRODUCTION ASSISTANCE FOR CELLULAR THERAPIES (PACT)- CELL PROCESSING FACILITIES CELL-TASK AREA 2, PCT0050-01: HESC-DERIVED CARDIOMYOCYTE PROGENITOR CE

City of Hope（COH）的生物医学和遗传学中心（CBG）是一个cGMP生产设施，致力于为COH研究人员及其合作者提供转化研究各个方面的支持，包括将基于实验室的新型和新兴细胞和基因治疗技术转化为中试规模临床前cGLP工艺和完全符合cGMP的生产工艺的专业知识。在该提案中，他们提议向PACT研究者Joseph Wu，MD，PhD（斯坦福大学医学院）提供人胚胎干细胞（hESC）衍生的心肌细胞（CM），以支持其提交IND的IND使能研究。

The Center for Biomedicine and Genetics (CBG) at City of Hope (COH) is a cGMP manufacturing facility dedicated to providing COH researchers and their collaborators support in all aspects of translational research, including expertise in translating laboratory-based procedures for novel and emerging cell and gene therapy technologies to pilot-scale pre-clinical cGLP processes and fully cGMP=compliant manufacturing processes. IN this proposal, they propose to supply human embryonic stem cell (hESC)-derived cardiomayocytes (CM) to PACT investigator, Joseph Wu, MD, PhD (Stanford School of Medicine), in support of his IND-enabling research for his submitted IND.