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T21RS Meeting June 2022 Long Beach, California

T21RS 会议 2022 年 6 月加利福尼亚州长滩

基本信息

批准号：
10469127
负责人：
Elizabeth Head
金额：
$ 3.75万
依托单位：
UNIVERSITY OF CALIFORNIA-IRVINE
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-04-05 至 2023-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10469127
关键词：
Address Advocate Aging Alzheimer&apos s Disease American Applied Research Area Award Basic Science Behavioral Brain COVID-19 pandemic California Cells Chicago Chromosome 21 Clinical Research Clinical Trials Cognition Cognitive Cognitive deficits Collaborations Communication Defect Down Syndrome Event Family Funding Future Genetic Genetic Research Goals Health Human Individual Intellectual functioning disability Intellectual impairment Intelligence International Investigation Knowledge Laboratories Longevity Mentors Nerve Degeneration Neurobiology Paris, France Persons Postdoctoral Fellow Quality of life Request for Applications Research Research Personnel Scientist Senior Scientist Societies Spain Structural defect Training and Education Translating Translational Research Travel United States National Institutes of Health Universities base career comorbidity design developmental disease developmental genetics effective therapy environmental enrichment for laboratory animals graduate student high risk improved innovation knowledge base meetings middle age neuron development neuropathology next generation novel pathological aging posters programs success symposium therapeutic target transcriptomics virtual

项目摘要

PROJECT SUMMARY/ABSTRACT Down syndrome (DS) is caused by the inheritance of three rather than the expected two copies of chromosome 21, or trisomy 21. DS is characterized by specific structural abnormalities in the brain, by a range of cognitive deficits and intellectual disability, and by a significantly high risk of developing Alzheimer disease by middle age. The rapid pace of progress in DS research that has taken place in the last decade highlights the critical need for effective communication between scientists, clinicians, families and self-advocates to take basic research discoveries from the laboratory to clinical trials that benefit people with DS. Advances in DS research are not only driven by senior scientists but are dependent up on the nurturing of our next generation of junior scientists. Thus, this application requests funding to cover travel expenses of American-based junior investigators, postdoctoral fellows and graduate students to attend the Fourth International conference of the Trisomy 21 Research Society (T21RS). Attendees at this meeting will include established DS and non-DS investigators whose research directly or indirectly informs critical aspects of DS cognition, neuropathology, translational opportunities and clinical trials. The meeting will take place in Long Beach, California from June 8 to June 12, 2022. Based on our previous successes, we anticipate that this conference will lead to fruitful discussions and novel collaborations that are essential to define the future of DS research. The theme of our meeting will be Imagine, Discover, Inspire.

项目总结/文摘