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Research Education Component

Research Education Component
研究教育部分
批准号:
10474608
负责人:
Xiongwei Zhu
金额:
$29.93万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-09-01 至 2026-06-30

项目摘要

项目成果

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中文摘要
翻译
项目总结 研究教育部分(REC)旨在满足阿尔茨海默病的两个关键需求 (AD)和阿尔茨海默病相关痴呆症(ADRD)社区:1)现有研究人员和 AD/ADRD的临床专家显然不足以满足AD迅速增加的需要 美国和世界各地的人口和2)我们在弥合知识差距方面取得了进展 通过多年的研究了解神经退行性变的机制,临床护理的进展 仍然缺乏。因此,新科学家在广泛的方法方面接受了深入的临床培训 需要赞赏以促进AD/ADRD领域的翻译研究取得进展并 制定创新和有效的诊断和治疗策略。REC计划具有 专门为选定的计划参与者设计,以提供严格的科学研究培训 AD/ADRD领域,以及广泛的临床暴露。 REC的具体目标是培养有才华和有前途的初级教员和研究助理,以及 通过明确阐述的个性化研究计划和指导计划支持他们的职业发展 目标。REC强调在神经退行性变的基础方面进行严格的科学培训,并 AD/ADRD相关疾病的发病机制及课堂教学的临床前景 相关实验室研究和带教神经退行性变临床经验与教育相结合 讨论临床和转化性AD/ADRD研究和职业发展的重要主题的论坛。 REC已经确定了一群不同的有前途的候选人,他们将被鼓励发展 在由杰出教师组成的教师指导委员会的指导下的新能力 项目学院包括临床和基础研究人员。REC还将利用大量的 通过与发改委有关的机构提供的教育和培训资源,包括正规的 计划、培训资助和其他教育资源,使确定的参与者能够 他们的研究生涯。该REC计划不仅将为培训提供必要的基础设施 新的AD/ADRD相关临床/基础研究人员,但也刺激了跨部门/跨学科 CADRC临床和基础科学研究人员之间的合作,以服务于加速 协作式健康服务、介入科学和转化性神经行为科学研究 特别是在AD/ADRD,加强了非洲发展研究中心以及国家和国际努力的活动。
英文摘要
PROJECT SUMMARY The Research Education Component (REC) is aimed at fulfilling two critical needs in the Alzheimer's disease (AD) and Alzheimer's disease related dementias (ADRD) community: 1) the number of current researchers and clinical specialists in AD/ADRD are clearly inadequate to meet the needs of the rapid increase in the AD population in the US and around world and 2) while we have made advances in bridging the knowledge gaps in understanding neurodegenerative mechanisms through many years of research, advances in clinical care are still lacking. As such, new scientists trained in the breadth of approaches with deep clinical appreciation are required to promote progress in translational research in the AD/ADRD field and to develop innovative and effective strategies for the diagnosis and the treatment. The REC program has been specifically designed for selected Program Participants to provide rigorous scientific research training in the AD/ADRD field along with extensive clinical exposure. The REC specifically aims to train talented and promising junior faculty and research associates and supports their career growth with individualized Research Plan and Mentoring Plan with clearly articulated goals. The REC emphasizes rigorous scientific training in fundamental aspects of neurodegeneration and mechanisms of diseases involving AD/ADRD and clinical perspectives through classroom teaching, AD/ADRD- related laboratory research and mentored neurodegenerative clinical experiences combined with educational forums that address important topics in clinical and translational AD/ADRD research and career growth. The REC has identified a group of diverse promising candidates who will be encouraged to develop new competencies under the mentorship of a faculty Mentoring committee composed of outstanding Program Faculty including both clinical and basic researchers. The REC will also utilize the vast educational and training resources available through CADRC-associated institutions including formal programs, training grants, and other educational resources to enable the identified participants to advance their research careers. This REC program will not only provide the necessary infrastructure for the training of new AD/ADRD-related clinical/basic researchers, but also stimulate interdepartmental/interdisciplinary collaborations among CADRC clinical and basic science researchers to serve the overall goal to accelerate collaborative health services, interventional science, and translational neurobehavioral science research specifically in AD/ADRD, augmenting activities of both the CADRC and national and international efforts.
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Role of Mettl3-dependent RNA m6A dysregulation in Alzheimer's disease
  • 批准号:
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