Training in Neurodegenerative Diseases

描述(申请人提供)：神经变性培训计划(NTP)的目标是在神经退行性疾病的各个方面和涉及神经退行性疾病的机制方面提供严格的博士前培训。一批优秀的受训人员将与世界级教师结合起来，研究与神经退行性变相关的广泛课题，研究领域包括蛋白质结构、细胞和分子生物学以及疾病的体外和体内模型。NTP涵盖多个部门、学校和机构，包括凯斯西部储备大学的多个系，特别是医学院及其附属机构、大学医院病例医疗中心(UHCMC)、路易·斯托克斯克利夫兰退伍军人管理医疗中心(VAMC)和克利夫兰临床基金会(CCF，包括勒纳研究所)。所有这些机构都在步行距离内，这种丰富的培训环境享有非常活跃的基础科学和临床活动以及最先进的资源，以丰富博士前实习生的培训，因为他们从事神经退化领域的基础和/或转换研究。NTP的培训包括NTP课程工作、正式和非正式研讨会、年度务虚会和出版学术出版物的研究经验。这一培训计划的一个独特组成部分是包括要求的一个学期，每周半天，在神经退行性疾病诊所的指导经验。NTP提供的授课和经验式培训机会相结合，将为学员未来在神经退行性变的科学研究领域奠定坚实的基础。

DESCRIPTION (provided by applicant): The goal of the Neurodegeneration Training Program (NTP) is to provide rigorous pre-doctoral training in various aspects of neurodegeneration and mechanisms of diseases involving neurodegeneration. An outstanding pool of trainees will combine with world-class faculty to investigate a wide range of neurodegeneration-related topics spanning research areas such as protein structure, cell and molecular biology and in vitro and in vivo models of disease. The NTP spans departments, schools and institutions to include multiple departments at Case Western Reserve University, particularly the School of Medicine, and its affiliated institutions, University Hospitals Case Medical Center (UHCMC), The Louis Stokes Cleveland Veteran's Administration Medical Center (VAMC), and the Cleveland Clinic Foundation (CCF, including the Lerner Research Institute). All of these institutions are within walking distance of each other and this rich training environment enjoys very active basic science and clinical activities and state of the art resources to enrich the training of pre- doctoal trainees as they engage in basic and/or translational research in the field of neurodegeneration. Training in the NTP involves NTP course work, formal and informal seminars, an annual retreat, and a research experience resulting in scholarly publications. A unique component of this training program is the inclusion of a required 1 semester, half day per week, mentored experience in a neurodegenerative disease clinic. The combination of didactic and experiential training opportunities afforded by the NTP will provide trainees a solid foundation for a future career in the scientific inquiry of neurodegeneration.