Rutgers Optimizes Innovation (ROI) Program

项目摘要/摘要 罗格斯大学优化创新(ROI)计划将提供一个垂直整合的机制，以迅速 发现有前景的生物医学产品发现，并无缝指导创新者通过 商业化进程，包括金融和监管、知识产权保护、指导、管理和教育 资源。利用罗格斯大学的生物医学/生物工程科学和罗格斯大学坚实的专业知识 研究商业化办公室(ORC)，我们将整合我们的优势来发现、开发和 将改善健康和福祉的发现商业化，培养下一代创新者。这个 ROI计划由罗格斯大学及其附属机构的一个合作机构组成，其中包括 工程、文理、医学院、护理、牙科、公共卫生和研究 研究所和中心、行业、孵化器、资助者和政策制定者。 所有实体都为ROI计划提供了大量资源，并为规划、开发、 以及合作社的领导组成。总部设在最具生产力的州之一 将与健康相关的发现(资产)商业化，ROI计划将作为翻译的平台 将生物医学发现转化为适销对路的产品。我们的REACH中心将确定与健康相关的创新 技术通过使用NCI资助的新泽西州癌症研究所(CINJ)、罗格斯研究所 转化医学和科学(RITMS，NCATS资助的CTSA的负责人)和生物材料中心， 由美国国家科学基金会和国防部资助。将评估这些技术的商业化可行性，特别是 在提供精确治疗以满足疾病异质性所产生的未得到满足的需求方面 发病机制和治疗反应。解决这些未得到满足的需求将为患者提供量身定做的资产 最终改善人口健康的治疗反应。 投资回报计划将提供一个简化和协调的基础设施，这将促进商业化 关于学术发现的。ROI计划中嵌入的教育计划将为我们的创新者提供 具有动手能力、实践性培训的产品开发和创业要求，同时培训形式多样 通过利用、合并和重新利用现有资源，包括i- Corps和iJOBS。实施独特的项目管理和指导计划，由行业、 疾病状态和内容专家也将增加创新者的成功机会。快速拥抱失败 哲学确保这项技术将以具有成本效益和市场意识的方式开发。横穿 All AIMS，ROI计划将与REACH联盟合作，在其先进的平台上为 商业化、技术审查和培训，并为财团提供我们的专业知识和承诺 作为积极参与的成员。重要的是，评估里程碑和指标在各个方面都进行了规划 投资回报计划以确保持续的质量评估、改进和可持续性。

Project Summary/Abstract The Rutgers Optimizes Innovation (ROI) Program will provide a vertically integrated mechanism to swiftly uncover promising biomedical product discoveries, and seamlessly guide the innovator through the commercialization process with financial and regulatory, IP protection, mentoring, management, and educational resources. Drawing on the biomedical/bioengineering sciences across Rutgers and on the solid expertise of the Office of Research Commercialization (ORC), we will integrate our strengths to uncover, develop and commercialize discoveries that improve health and well-being, and train the next generation of innovators. The ROI Program comprises a cooperative of Rutgers University and affiliates that includes the schools of engineering, arts and sciences, schools of medicine, nursing, dental science, public health, and research institutes and centers, industries, incubators, funders and policymakers. All entities provide significant resources to the ROI Program and have contributed to the planning, development, and leadership composition of the cooperative. Based in one of the most productive states with respect to commercialization of health-related discoveries (assets), the ROI Program will serve as a platform for translating biomedical discoveries into marketable products. Our REACH Hub will identify innovative health-related technologies by using the expertise of the NCI-funded Cancer Institute of NJ (CINJ), the Rutgers Institute for Translational Medicine and Science (RITMS, lead of the NCATS-funded CTSA) and the Biomaterials Center, funded by NSF and DOD. These technologies will be evaluated for commercialization feasibility, especially with respect to providing precision therapy to tackle an unmet need created by the heterogeneity of disease pathogenesis and response to treatment. Addressing such unmet needs will provide assets tailored to patients’ therapeutic responses that ultimately improves population health. The ROI Program will provide a streamlined and harmonized infrastructure that will enhance commercialization of academic discovery. The educational programs embedded in the ROI Program will provide our innovators with hands-on, practical training in product development and start-up requirements, while also training a diverse workforce in biomedical innovation by leveraging, coalescing and repurposing current resources, including I- Corps and iJOBS. Implementing a unique project management and mentoring program comprised of industry, disease-state and content experts will also enhance innovators’ opportunity for success. Embracing a Fail Fast Philosophy assures the technology will be developed in a cost-effective and market-conscious manner. Across all Aims, the ROI Program will collaborate with the REACH Consortium to build on their advances in platforms for commercialization, technology review, and training, and provide the Consortium with our expertise and commitment to serve as an active participating member. Importantly, evaluation milestones and metrics are planned in all aspects of the ROI Program to assure continuous quality assessment, improvement and sustainability.