Developmental Funds

发展基金

• 批准号: 10580695
• 负责人: STEVEN K. LIBUTTI
• 金额: $ 36.85万
• 依托单位: RUTGERS BIOMEDICAL AND HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10580695
• 关键词: Achievement; Applications Grants; Area; Award; Basic Science; Bioinformatics; Cancer Center Support Grant; Cancer Institute of New Jersey; Catchment Area; Categories; Chemistry; Clinical Research; Collaborations; Computational Biology; Critiques; Data; Development; Disparity; Evaluation; Evolution; Faculty; Faculty Recruitment; Fostering; Funding; Genomics; Goals; Grant; Growth; Immunologic Monitoring; Immunology; Immunooncology; Immunotherapy; Individual; Institution; Investments; Laboratories; Leadership; Medical Oncology; Methodology; Molecular Epidemiology; Monitor; Neuroendocrine Tumors; Peer Review; Peer Review Grants; Philanthropic Fund; Pilot Projects; Population Research; Population Sciences; Process; Protocols documentation; Recording of previous events; Research; Research Personnel; Research Support; Resource Sharing; Resources; Strategic Planning; Surgical Oncology; Systems Biology; Technical Expertise; Tobacco; Universities; Vision; cancer pharmacology; career; cost; engineered T cells; innovation; instrumentation; member; metabolomics; novel; precision medicine; programs; recruit; research study; screening; small molecule

DEVELOPMENTAL FUNDS PROJECT SUMMARY/ABSTRACT CCSG developmental funds leveraged additional institutional support and provided an exceptionally strong return on investment. The $350,000 CCSG support of the New Investigator Award Program was supplemented by $80,000 of institutional/philanthropic funds, allocated to eight new faculty recruits, and generated a total of $9 million (total costs) in grant support. The $1.2 million CCSG support of the Pilot Project Program was supplemented by $1.5 million of institutional/philanthropic funds, generating $17.8 million (total costs) in grant support. The grand total of $26.8 million return on investment (ROI) includes over $26.6 million in peer reviewed grant support, and represents a 17.5-fold ROI of CCSG funds invested for New Investigator Awards and Pilot Projects. CCSG developmental funds further enabled shared resource evolution. The Metabolomics shared resource has matured to an established shared resource that offers unique technical expertise and ease-of-access to state-of-the-art instrumentation and current protocols that are not available in most individual investigator laboratories; this resource continues to fuel collaborative research with Princeton University and over a recent twelve-month period, served 19 investigators (17 of whom are CINJ members) across three CINJ programs. Given the continued substantial growth of the CINJ research enterprise, and the successful use of developmental funds in the current project period, we request $425,000 per year to be used in three categories: 1) recruitment of investigators in areas of strategic priority for CINJ (New Investigator Award program), 2) development of new shared resources in Immune Monitoring (responding to the Director’s initiative in Immune Oncology) and Small Molecule Screening (critical to all Basic programs and specifically responsive to a 2011 critique of the Cancer Pharmacology Program), and 3) pilot awards (Pilot Project program) to promote novel, collaborative research aligned with strategic priorities.

财务基金 项目总结/摘要 CCSG发展基金利用了额外的机构支持，并提供了非常强大的 投资回报率新研究者奖计划的35万美元CCSG支持是 由80，000美元的机构/慈善基金补充，分配给8名新教师， 总共产生了900万美元的赠款支助（费用总额）。120万美元的CCSG对试点项目的支持 项目方案得到了150万美元的机构/慈善基金的补充，产生了1780万美元的资金。 100万美元（总费用）的赠款支助。总计2680万美元的投资回报率（ROI）包括 超过2660万美元的同行评审赠款支持，代表了CCSG资金投资的17.5倍投资回报率 新的研究者奖和试点项目。 CCSG发展基金进一步促进了共享资源的发展。Metabolomics分享资源 已经成熟为一个既定的共享资源，提供独特的技术专长和易于访问， 大多数个体研究者无法获得最先进仪器和当前方案 该资源继续推动与普林斯顿大学的合作研究，并在最近的一次 在为期12个月的时间里，为19名研究人员（其中17人是CINJ成员）提供了三个CINJ项目的服务。 鉴于CINJ研究企业的持续大幅增长，以及成功使用 在本项目期间，我们要求每年425，000美元用于三个项目 类别：1）在CINJ（新调查员奖）战略优先领域招聘调查员 计划），2）在免疫监测中开发新的共享资源（响应主任的 免疫肿瘤学倡议）和小分子筛查（对所有基础计划至关重要， 响应2011年癌症药理学计划的评论），和3）试点奖（试点项目 计划），以促进新的，与战略重点一致的合作研究。