Rutgers Optimizes Innovation (ROI) Program

罗格斯大学优化创新 (ROI) 计划

• 批准号: 10022340
• 负责人: STEVEN K. LIBUTTI
• 金额: $ 100万
• 依托单位: RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-23 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10022340
• 关键词: Abbreviations; Academia; Address; Arts; Biocompatible Materials; Biomedical Engineering; Biomedical Research; Biomedical Technology; Businesses; Clinical; Collaborations; Conscious; Dental; Development; Diagnostic; Discipline; Discipline of Nursing; Disease; Diverse Workforce; Engineering; Evaluation; Fostering; Funding; Future; Government; Health; Healthcare; Incubators; Industry; Infrastructure; Innovation Corps; Institutes; Laboratories; Lead; Leadership; Malignant Neoplasms; Mentors; Mission; Modeling; New Jersey; Pathogenesis; Pathway interactions; Patient Rights; Patients; Personal Satisfaction; Philosophy; Precision therapeutics; Probability; Process; Public Health; Public Health Schools; Research; Research Institute; Resources; School Nursing; Schools; Science; Societies; Solid; Technology; Therapeutic; Time; Training; Translating; Translational Research; Universities; Vision; base; care outcomes; commercialization; cost effective; design; disease heterogeneity; education resources; improved; innovation; medical schools; member; next generation; population health; precision medicine; product development; programs; success; translational medicine; treatment response

Project Summary/Abstract The Rutgers Optimizes Innovation (ROI) Program will provide a vertically integrated mechanism to swiftly uncover promising biomedical product discoveries, and seamlessly guide the innovator through the commercialization process with financial and regulatory, IP protection, mentoring, management, and educational resources. Drawing on the biomedical/bioengineering sciences across Rutgers and on the solid expertise of the Office of Research Commercialization (ORC), we will integrate our strengths to uncover, develop and commercialize discoveries that improve health and well-being, and train the next generation of innovators. The ROI Program comprises a cooperative of Rutgers University and affiliates that includes the schools of engineering, arts and sciences, schools of medicine, nursing, dental science, public health, and research institutes and centers, industries, incubators, funders and policymakers. All entities provide significant resources to the ROI Program and have contributed to the planning, development, and leadership composition of the cooperative. Based in one of the most productive states with respect to commercialization of health-related discoveries (assets), the ROI Program will serve as a platform for translating biomedical discoveries into marketable products. Our REACH Hub will identify innovative health-related technologies by using the expertise of the NCI-funded Cancer Institute of NJ (CINJ), the Rutgers Institute for Translational Medicine and Science (RITMS, lead of the NCATS-funded CTSA) and the Biomaterials Center, funded by NSF and DOD. These technologies will be evaluated for commercialization feasibility, especially with respect to providing precision therapy to tackle an unmet need created by the heterogeneity of disease pathogenesis and response to treatment. Addressing such unmet needs will provide assets tailored to patients’ therapeutic responses that ultimately improves population health. The ROI Program will provide a streamlined and harmonized infrastructure that will enhance commercialization of academic discovery. The educational programs embedded in the ROI Program will provide our innovators with hands-on, practical training in product development and start-up requirements, while also training a diverse workforce in biomedical innovation by leveraging, coalescing and repurposing current resources, including I- Corps and iJOBS. Implementing a unique project management and mentoring program comprised of industry, disease-state and content experts will also enhance innovators’ opportunity for success. Embracing a Fail Fast Philosophy assures the technology will be developed in a cost-effective and market-conscious manner. Across all Aims, the ROI Program will collaborate with the REACH Consortium to build on their advances in platforms for commercialization, technology review, and training, and provide the Consortium with our expertise and commitment to serve as an active participating member. Importantly, evaluation milestones and metrics are planned in all aspects of the ROI Program to assure continuous quality assessment, improvement and sustainability.

项目概要/摘要 罗格斯大学优化创新 (ROI) 计划将提供一个垂直整合的机制，以快速 发现有前景的生物医学产品发现，并无缝地引导创新者完成整个过程 商业化过程涉及财务和监管、知识产权保护、指导、管理和教育 资源。借鉴罗格斯大学的生物医学/生物工程科学和扎实的专业知识 研究商业化办公室（ORC），我们将整合我们的优势来发现、开发和 将改善健康和福祉的发现商业化，并培训下一代创新者。这 ROI 计划由罗格斯大学及其附属机构组成的合作社组成，其中包括以下学校： 工程学院、艺术与科学学院、医学院、护理学院、牙科科学学院、公共卫生学院和研究学院 机构和中心、行业、孵化器、资助者和政策制定者。 所有实体都为 ROI 计划提供了大量资源，并为规划、开发、 以及合作社领导班子的组成。位于生产力最高的州之一 投资回报率计划将作为与健康相关的发现（资产）的商业化平台 将生物医学发现转化为可销售的产品。我们的 REACH 中心将识别与健康相关的创新 利用 NCI 资助的新泽西州癌症研究所 (CINJ)、罗格斯大学癌症研究所的专业知识来开发技术 转化医学和科学（RITMS，NCATS 资助的 CTSA 的领导者）和生物材料中心， 由美国国家科学基金会和国防部资助。将评估这些技术的商业化可行性，特别是 尊重提供精准治疗来解决疾病异质性造成的未满足的需求 发病机制和对治疗的反应。解决此类未满足的需求将提供适合患者的资产 最终改善人群健康的治疗反应。 ROI 计划将提供简化且统一的基础设施，以增强商业化 的学术发现。 ROI 计划中嵌入的教育计划将为我们的创新者提供 在产品开发和启动要求方面提供动手实践培训，同时还培训多样化的人员 通过利用、合并和重新利用现有资源，包括 I- 军团和 iJOBS。实施由行业、 疾病状态和内容专家还将增加创新者的成功机会。拥抱快速失败 理念确保该技术将以具有成本效益和市场意识的方式开发。穿过 为了实现所有目标，ROI 计划将与 REACH 联盟合作，以他们在平台方面的进步为基础 商业化、技术审查和培训，并向联盟提供我们的专业知识和承诺 作为积极参与的成员。重要的是，各个方面都规划了评估里程碑和指标 投资回报率计划，以确保持续的质量评估、改进和可持续性。