Administrative Core

ORDCC行政核心项目摘要 俄克拉荷马州风湿性疾病研究核心中心（ORDRCC）促进了风湿性关节炎的合作。 疾病研究，提供尖端技术来解决新的临床相关问题，招募 具有其他兴趣/接受过风湿性疾病研究培训的研究者， 研究人员到独立的风湿性疾病研究事业。25名当地中心研究者，11名初级研究者 中心研究者（当地）、11名初级中心研究者（远程）和一个新的学者项目，以开发 致力于风湿性疾病研究的早期研究者， 作为中央通信枢纽和信息管道，以完成扩大后的应急救援协调中心 使命是为每例研究患者提供详细的个性化信息，以便研究者选择 同质的，机械驱动的患者子集，用于研究发病机制，预测，预防和 精确治疗SLE、干燥综合征、UCTD及相关疾病。该ORDRCC将提高职业生涯 发展初级研究人员，并通过多管齐下的方法扩大风湿性疾病的研究 风湿病临床研究丰富计划，包括每周一次的系列研讨会，访问 讲座，以及一个新的扩大风湿性疾病座谈会举行了一个新的小组，每个 季度探索新的合作研究领域，如与雷诺兹老龄化中心， 生物工程，院长麦基眼科研究所，和其他人。对社区的额外外联沟通- 还计划建立伙伴和部落社区。行政核心将加强沟通 通过新的在线资源、列表服务和更新;通过制定的政策提供管理， 监督和优化资源利用的程序，优先为初级中心提供服务 研究人员和学者;并在行政核心内建立一个新的提案开发中心， 帮助初级中心研究员和学者准备和提交手稿和竞争性资助 应用.核心还协助初级中心研究人员和学者遵守法规 上级要员该ORDRCC有一个历史上充满活力的试点项目计划，推出了独立的 16名初级调查员的职业生涯，他们已经获得了超过2000万美元的独立外部赠款 支持.该核心将继续提供这一方案，该方案将适度的财政支持与优先考虑的 核心资源、重点辅导和职业发展计划。行政核心还作为 与咨询委员会互动的关键，以确保各项建议得到审查， 切实贯彻该中心实施了严格的定性和定量跟踪和评估 项目评估有助于监测和最大限度地利用资源和科学发现。这些 定性调查还有助于确定战略中心的优先事项，优先考虑表型服务和新的 评估和识别需要扩展或进一步增强的患者集合的技术。

ORDRCC Administrative Core Project Summary The Oklahoma Rheumatic Disease Research Cores Center (ORDRCC) facilitates collaborative rheumatic disease research, provides cutting-edge technologies to address new clinically-relevant questions, recruits investigators with other interests/training to rheumatic disease investigation and fosters development of junior investigators to independent rheumatic disease research careers. With 25 local Center Investigators, 11 Junior Center Investigators (local), 11 Junior Center Investigators (distant) and a new Scholar program to develop early stage investigators committed to rheumatic disease investigation, the ORDRCC Administrative Core serves as the central communications hub and information conduit to accomplish the expanded ORDRCC mission to provide detailed, individualized information for each study patient to allow investigators to select homogeneous, mechanistic-driven subsets of patients for studies of pathogenesis, prediction, prevention and precision treatment of SLE, Sjogren’s, UCTD and related disorders. The ORDRCC will enhance the career development of junior investigators and expand rheumatic disease research through a multi-pronged Rheumatic Disease Clinical Research Enrichment Program which includes a weekly seminar series, visiting lectureships, and a new Expanding Rheumatic Disease Colloquium held in conjunction with a new group each quarter to explore new areas of collaborative research, such as with the Reynolds Center on Aging, OU Bioengineering, Dean McGee Eye Institute, and others. Additional outreach communication to community- based partners and tribal communities is also planned. The Administrative Core will enhance communication through new online resources, listserves and updates; provide management through developed policies and procedures for oversight and optimization of resource utilization, prioritizing service to junior center investigators and Scholars; and develop a new Proposal Development Center within the Administrative Core to help junior center investigators and Scholars to prepare and submit manuscripts and competitive grant applications. The Core also assists Junior Center Investigators and Scholars with regulatory compliance oversight. The ORDRCC has a historically vibrant pilot project program which has launched the independent careers of 16 junior investigators who have gone on to receive over $20M in independent external grant support. This Core will continue to offer this program which couples modest financial support with prioritized Core resources, focused mentoring and a career development plan. The Administrative Core also serves as the nidus for interactions with the Advisory Committee to ensure that suggestions are reviewed and implemented. The ORDRCC has implemented a rigorous qualitative and quantitative tracking and evaluation program evaluation which helps to monitor and maximize resource utilization and scientific discoveries. These qualitative surveys also help to set strategic Center priorities, prioritize phenotyping services and new technologies to evaluate and identify the patient collections which need expansion or further enhancement.