New Electrodes for Enabling Inclusive EEG Monitoring in Black Populations

新电极可实现黑人群体的包容性脑电图监测

• 批准号: 10484809
• 负责人: Jasmine Kwasa
• 金额: $ 12.78万
• 依托单位: PRECISION NEUROSCOPICS, INC
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10484809
• 关键词: American; Attention; Awareness; Black Populations; Black race; Brain Diseases; Brain Injuries; Child; Clinic; Clinical; Clinical Research; Collaborations; Coma; Communities; Data; Diagnosis; Diagnostic Equipment; Disease; Down Syndrome; Electrodes; Electroencephalography; Ensure; Environment; Epilepsy; Exclusion Criteria; Gold; Hair; Healthcare; Hour; Individual; Industry; Injury; Intervention; Laws; Lead; Medical; Medical center; Modality; Monitor; Neurosciences; Noise; Participant; Patients; Pediatric Hospitals; Performance; Policies; Population; Porifera; Positioning Attribute; Procedures; Quality of Care; Questionnaires; Research; Research Personnel; Scalp structure; Signal Transduction; Skin; Stroke; System; Techniques; Testing; Time; United States National Institutes of Health; United States Public Health Service; Universities; Work; autism spectrum disorder; black patient; comorbidity; density; design; electric impedance; experience; implicit bias; improved; innovation; multidisciplinary; nervous system disorder; next generation; novel; relating to nervous system; response; standard of care; success; supportive environment; treatment disparity

Electroencephalography (EEG) -- a neural sensing modality essential for diagnosis of epilepsy, stroke, brain injuries and other neurological disorders -- is not accessible to individuals with coarse and curly hair common in Black populations. The springiness of these hair-types makes it difficult to maintain a good electrodes-scalp contact. Consequently, Black patients are denied the same quality of care as others. Our team has designed the first electrodes -- Sevo electrodes1, and complementary hair-braiding techniques -- that work with these hair-types. In the proposed work, Precision Neuroscopics will rigorously quantify improvement in EEG metrics obtained using Sevo electrodes in clinical and research lab settings, as well as obtain new designs that broaden the applicability and market of Sevo. Aim 1 will test Sevo electrodes in a) clinical setting, comparing with clinical standard systems and electrodes; and b) neuroscience lab setting, comparing with state-of-the-art systems used in neuroscience labs. Aim 2 will broaden the applicability and the market for Sevo by designing i) braid-free electrodes; ii) embedding novel conductive sponge electrodes to obtain electrodes that are quick-apply and yet can be used for a long time; iii) electrodes designed high-density EEG installation. By testing rigorously in a clinical setting, we test our electrodes on a relevant population, namely, children suffering from epilepsy. While our electrodes will help all patients and participants with this hair-type, they will be of even greater help for patients with Down’s syndrome and autism spectrum, who find it difficult to have EEG electrodes applied on their scalp, a difficulty compounded for Black patients suffering from these disorders. The project can thus support the NIH INCLUDE initiative (https://www.nih.gov/include-project) specific to Down’s syndrome patients, and broadly, enable inclusive NIH studies as required by federal law (Public Health Service Act sec. 492B, 42 USC 289a-2) and NIH policy.

脑电图（EEG）——一种对癫痫、中风、脑病的诊断至关重要的神经传感方式