Peer Support for Lowering Blood Pressure among Adolescents: A Pilot, Randomized Controlled Trial

同伴支持降低青少年血压：一项随机对照试验

• 批准号: 10508121
• 负责人: Shakia Tranece Hardy
• 金额: $ 14.61万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10508121
• 关键词: 17 year old; Academic skills; Academy; Active Learning; Address; Adherence; Adolescence; Adolescent; Adoption; Adult; Affect; Alabama; American; Behavior; Black race; Blood Pressure; Body Weight decreased; Cardiovascular Diseases; Cardiovascular system; Childhood; Church; Clinic; Clinical; Cluster randomized trial; Communities; Counseling; DASH diet; Data; Development; Diastolic blood pressure; Dietary Practices; Doctor of Philosophy; Education; Educational Curriculum; Epidemiology; Evaluation; Face; Feedback; Focus Groups; Food; Funding; Goals; Grant; Guidelines; Health behavior; Health education; Healthy Eating; High Prevalence; Hypertension; Individual; Intervention; Interview; K-Series Research Career Programs; Lead; Leadership; Life; Life Style; Life Style Modification; Medicine; Mentors; Mentorship; Methods; Morbidity - disease rate; North Carolina; Obesity; Parents; Participant; Pediatrics; Persons; Physical activity; Pilot Projects; Population Sciences; Positioning Attribute; Preventive Medicine; Principal Investigator; Process Measure; Protocols documentation; Publishing; Randomized Controlled Trials; Reach Effectiveness Adoption Implementation and Maintenance; Recommendation; Reduce health disparities; Research; Research Personnel; Rural; Rural Community; Scientist; Self Efficacy; Self Management; Site; Structure; Surveys; Testing; Time; Training; Travel; Universities; acceptability and feasibility; base; behavior change; behavior change wheel; blood pressure elevation; blood pressure reduction; cardiovascular disorder epidemiology; cardiovascular disorder risk; cardiovascular health; career development; contextual factors; design; didactic education; dietary; effective intervention; effectiveness testing; effectiveness trial; experience; feasibility testing; future implementation; health care availability; health disparity; health equity; healthy lifestyle; implementation intervention; implementation science; improved; intervention delivery; mortality; patient-clinician communication; payment; peer; peer support; pilot test; preempt; professor; programs; racial disparity; recruit; research and development; rural environment; rural residence; satisfaction; skills; social epidemiology; social health determinants; success; tenure track; theories; therapy development; uptake

ABSTRACT This K01 career development proposal was developed to support Dr. Shakia Hardy, a tenure track Assistant Professor in the Department of Epidemiology at the University of Alabama at Birmingham (UAB), in her path towards becoming an independent researcher. The Candidate earned her PhD in Epidemiology in 2017 from the University of North Carolina at Chapel Hill and has a strong record of published research in the fields of cardiovascular and social epidemiology. Her goal is to integrate her epidemiology skills with implementation science to develop an independent research program at the intersection of implementation and population science. Dr. Hardy’s research aims to reduce health disparities in cardiovascular disease through the modification of lifestyle behaviors that contribute to increased blood pressure in early life. Training: To accomplish her overall goal, Dr. Hardy has proposed an intensive mentored research plan that includes didactic education, and experiential learning in 1) intervention development, 2) implementation science for intervention delivery and evaluation, 3) design and conduct of randomized controlled trials, and 4) leadership skills for academic scientists. Mentorship: An interdisciplinary team of renowned scholars will mentor Dr. Hardy and provide ongoing guidance as she transitions to independence. Her mentoring team includes a Primary Mentor, Dr. Andrea Cherrington (Department of Preventive Medicine, UAB), co-Mentors, Dr. Paul Muntner (Department of Epidemiology, UAB), Dr. Nathalie Moise (Department of Medicine, Columbia University) and Dr. Daniel Feig (Department of Medicine, UAB) and two content advisors at UAB. Each of these mentors are fully committed to this project and to Dr. Hardy’s success. Research: The prevalence of high BP, defined as systolic BP (SBP) ≥120 mm Hg or diastolic BP (DBP) ≥80 mm Hg, is two-times higher (20% versus 10%) among Black versus white adolescents 13-17 years of age in the US. The availability of lifestyle behavior counseling in a clinical setting to lower BP is limited in rural communities due to long travel distances to access healthcare, limited funds for co-payments, and ineffective provider-patient communication. The proposed K01 addresses this gap by developing and testing the feasibility and acceptability of a peer support intervention to lower BP among rural Black adolescents with high BP. First, Dr. Hardy will identify aspects of the rural environment that present barriers to lifestyle behavior change. Next, using the behavior change wheel for intervention development, she will develop and pilot test a peer support intervention devised to address these barriers. The successful completion of this project will lead to an R01 grant submission to test the effectiveness of this peer support intervention in a multi-site cluster-randomized trial and allow Dr. Hardy to become an independent investigator contributing to health equity among adolescents, where lifestyle behavior change could preempt the development of racial disparities in BP and cardiovascular morbidity and mortality.

摘要