West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health

西弗吉尼亚州临床和转化科学研究所：全州范围内的组织，致力于打造卓越研究并吸引社区改善健康

• 批准号: 10505663
• 负责人: Sally Lynn Hodder
• 金额: $ 425.18万
• 依托单位: WEST VIRGINIA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10505663
• 关键词: 2019-nCoV; Academic Medical Centers; Address; Alzheimer' s Disease; Appalachian Region; Award; COVID-19 pandemic; COVID-19 patient; Cardiovascular Diseases; Categories; Chronic Disease; Chronic lung disease; Clinical; Clinical Research; Clinical Sciences; Cohort Studies; Collaborations; Color; Communities; Community Outreach; County; Development; Environmental Hazards; Epidemic; Exposure to; Funding; Goals; Grant; HIV; Health; Health Resources; Human; Human Resources; Incidence; Institutes; Lead; Leadership; Life Expectancy; Malignant Neoplasms; Medical center; National Institute for Occupational Safety and Health; Osteopathic Medicine; Outcome; Policies; Positioning Attribute; Post-Acute Sequelae of SARS-CoV-2 Infection; Primary Health Care; Productivity; Public Health; Publications; Registries; Research; Research Infrastructure; Research Personnel; Rural Community; Rural Health; Rural Population; Science; Scientist; Site; Substance Use Disorder; Testing; Training; Training Support; Translational Research; Trust; United States; United States Department of Veterans Affairs; United States National Institutes of Health; West Virginia; Work; addiction; cohort; coronavirus disease; diversity and equity; health care service organization; health disparity; improved; medical schools; mortality; next generation; practice-based research network; predictive modeling; programs; reproductive; substance use; success; translational scientist

West Virginia (WV), the only state located entirely in Appalachia, has the lowest life expectancy in the nation and ranks at or near the bottom in many chronic disease categories. The WV Clinical and Translational Science Institute (WVCTSI) was created in 2012 through the initial Institutional Development Award for Clinical and Translational Research (IDeA-CTR) and successfully renewed in 2017. Over the past 9 years, WVCTSI has cultivated and nurtured a highly collaborative, statewide research infrastructure to address the substantial health disparities in WV. Over the past 4 years, WVCTSI productivity has been superb with 1,325 publications, 951 funding applications, and 688 external funding awards totaling $159.3 MM. The WVCTSI’s overarching goal for the next funding cycle is to serve as a transformational force, leading statewide clinical and translational collaborative research that positively impacts health outcomes in WV. We will achieve this goal through the following specific aims: Specific Aim 1 - Build collaborative, productive research infrastructure across WV that substantively contributes to improving WV health outcomes, Specific Aim 2 - Train and position for success the next generation of clinical and translational scientists, and Specific Aim 3 - Actively engage multiple stakeholders, including rural communities, in research and effectively disseminate research results to rural populations in a manner that facilitates understanding and trust. There are 3 important cross-cutting themes around which our efforts will be focused that include: 1) Rural Health, 2) Diversity, Equity, and Inclusion (engaging not only WV’s rural communities but also WV’s communities of color; equally important is supporting diverse investigators), and 3) the clinician scientists of tomorrow – able to frame the right questions and work to find the answers. Central to attainment of our specific aims is the highly collaborative statewide organization that WVCTSI has developed over the preceding 9 years and that now includes every major healthcare organization and academic medical center in WV, the state health department (WVDHHR), the National Institute for Occupational Safety and Health, and >100 primary care organizations across WV that constitute the WV Practice-Based Research Network. Equally important is the high level of collaboration and commitment among WVCTSI’s cores. Successful completion of our objectives will inform policy, practice, and community changes resulting in improved WV health outcomes.

西弗吉尼亚州是唯一一个完全位于阿巴拉契亚的州， 在许多慢性病类别中处于或接近底部。WV临床和 翻译科学研究所（WVCTSI）成立于2012年，通过最初的机构 临床和转化研究发展奖（IDEA-CTR），并于 2017.在过去的9年里，WVCTSI培养和培育了一个高度协作的，全州范围内的 研究基础设施，以解决西弗吉尼亚州的重大健康差距。在过去的四年里， WVCTSI的生产力一直是一流的1，325出版物，951资助申请，688 外部资金奖励总额为1.593亿美元。WVCTSI下一次资助的总体目标 循环是作为一个转型的力量，领导全州的临床和翻译合作 对西弗吉尼亚州健康结果产生积极影响的研究。我们将通过以下方式实现这一目标 具体目标：具体目标1 -在西弗吉尼亚州建立协作的、富有成效的研究基础设施， 具体目标2 -培训和定位， 下一代临床和转化科学家的成功，以及具体目标3 -积极参与 包括农村社区在内的多方利益攸关方参与研究，并有效传播研究成果 以促进理解和信任的方式向农村人口提供成果。有三个重要的 我们的工作重点将围绕交叉主题，包括：1）农村卫生，2）多样性， 公平和包容（不仅涉及西弗吉尼亚州的农村社区，也涉及西弗吉尼亚州的有色人种社区; 同样重要的是支持不同的研究者），以及3）明天的临床科学家-能够 提出正确的问题并努力寻找答案。实现我们具体目标的核心 是WVCTSI在过去9年中发展起来的高度协作的全州组织。 多年来，现在包括每一个主要的医疗保健组织和学术医疗中心在西弗吉尼亚州， 州卫生部、国家职业安全与健康研究所，以及 超过100个初级保健组织在西弗吉尼亚州，构成西弗吉尼亚州的实践为基础的研究网络。 同样重要的是WVCTSI核心之间的高水平协作和承诺。 成功完成我们的目标将告知政策，实践和社区的变化 改善西弗吉尼亚州的健康状况。