West Virginia IDEA-CTR

描述(由申请人提供)：西弗吉尼亚州临床与翻译科学研究所(WVCTSI)的IDEA-CTR应用程序的目标是将我们的临床和翻译研究的基础设施和实践扩展到与临床和翻译科学奖(CTSA)竞争的水平。为此，WVCTSI于2008年成立，作为支持研究的组织之家，以满足西弗吉尼亚州和阿巴拉契亚中部人民的健康和保健需求，并最终消除健康差距。为了实现我们雄心勃勃的目标，包括西弗吉尼亚大学、查尔斯顿地区医学中心、西弗吉尼亚骨科医学院和西弗吉尼亚联合卫生系统在内的WVCTSI与阿巴拉契亚翻译研究所建立了合作伙伴关系，后者是由我们的IDEA州合作伙伴和CTSA获得者肯塔基大学创建的。WVCTSI将通过追求三个目标来实现其目标：1)将WVCTSI发展成为针对癌症、心血管中风和肥胖相关疾病的临床和翻译研究的学术家园和催化剂；2)在WVCTSI合作的机构和肯塔基大学、俄亥俄州立大学和印第安纳大学的协作CTSA之间建立跨领域的研究伙伴关系，以提高我们的研究能力；以及3)利用创新的招聘、培训和指导策略，在每个WVCTSI机构培养临床和翻译科学家。这些目标通过招募和支持临床和转化型科学家以及广泛的教育和指导计划来实现。此外，参与的教员还可以获得包括生物统计学、临床信息学和一系列试点资助机制在内的研究资源。此外，正在制定各种机制，以便在不损害对人类主体保护的情况下精简监管程序，并使社区充分参与研究议程。最后，为了确保问责制和质量改进，已经建立了一个强有力的评估方案。总体而言，WVCTSI已经建立了强大的基础设施，以增加外部资助的临床和翻译研究人员的数量，并制定了一个经过深思熟虑的计划，以提高未来五年的能力和生产率，为我们在CTSA中的竞争力做好准备。

DESCRIPTION (provided by applicant): The goal of the West Virginia Clinical and Translation Science Institute's (WVCTSI) IDeA-CTR application is to expand our infrastructure for, and practice of, clinical and translational research to a level competitive for a Clinical and Translational Science Award (CTSA). To this end, the WVCTSI was established in 2008 as the organizational home supporting research to address the health and healthcare needs of the people of West Virginia and Central Appalachia, and ultimately to eliminate health disparities. To realize our ambitious goal, the WVCTSI, which includes West Virginia University, Charleston Area Medical Center, West Virginia School of Osteopathic Medicine, and West Virginia United Health Systems, has partnered with the Appalachian Translational Research Institute, which was founded by our IDeA state partner and CTSA recipient the University of Kentucky. The WVCTSI will achieve its goal through pursuit of three aims: 1) Grow the WVCTSI as an academic home and a catalyst for clinical and translational research that targets cancer, cardiovascular-stroke, and obesity related diseases; 2) Establish cross cutting research partnerships among the WVCTSI partnered institutions and collaborating CTSAs at University of Kentucky, Ohio State University, and Indiana University to increase our research capacity; and 3) Utilize innovative recruitment, training, and mentoring strategies to develop clinical and translational scientists at each of the WVCTSI institutions. These aims are addressed through recruitment and support of clinical and translational scientists and a broad educational and mentoring program. In addition, participating faculty are provided with research resources that include biostatistics, clinical informatics, and access to a range of pilot funding mechanisms. Furthermore, mechanisms to streamline regulatory processes without compromising human subject protections and to engage communities fully in the research agenda are being developed. Finally, to ensure accountability and quality improvement, a robust evaluation program has been established. Overall, the WVCTSI has developed a strong infrastructure to increase the number of extramural funded clinical and translational researchers and has a well-considered plan for enhancing capacity and productivity over the next five years, positioning us for competitiveness for a CTSA.