Prevention of Paralytic Shellfish Poisoning in Subsistence Shellfish Harvest Communities of Southeast Alaska

摘要摘要 麻痹性贝类中毒(PSP)是一种严重的疾病，对阿拉斯加土著居民的影响不成比例 社区。阿拉斯加州的锡特卡部落组织了一个环境监测项目和海鲜安全 与其他地区合作伙伴(称为Seator：阿拉斯加东南部部落海洋研究)共同开展的测试计划 以减轻阿拉斯加东南部PSP疾病的负担。这笔赠款旨在扩大Seator正在进行的 通过更多的数据收集以及与锡特卡学区和埃默里大学的伙伴关系，开展了多项工作。 使用与今天相同的协议收集额外几年的PSP毒素监测数据将允许一段时间- 系列分析为尖端预测模型提供信息，该模型将向阿拉斯加东南部居民发出警告 特别是危险的生存贝类收获时间，从而防止中毒。在以下位置收集新数据 特定种类的PSP毒素(而不是只测量任何PSP毒素的存在或不存在)可以澄清 世界各地的哪些其他环境最相似(例如，通过比较毒素图谱)。这事很重要 因为PSP是一个全球健康问题，还有其他地方可以受益于信息性 预测模型，或者可能能够为开发该区域的模型提供有用的信息。 Seator将继续通过研讨会培训社区成员如何收集和处理 正在进行的工作的每个公民科学框架的样本。该项目还包括计划中的K12 采取教育干预措施，向处于PSP中毒特别风险的青年提供预防PSP的信息，同时 还促进科学教育和传统生活方式。这个项目是完全基于社区的参与性项目。 研究(CBPR)建立在现有部落组织方案的基础上，包括就业和技能培训 为社区成员提供机会，满足社区优先考虑的需求并解决这一健康问题 贫富差距。

SUMMARY ABSTRACT Paralytic shellfish poisoning (PSP) is a serious illness that disproportionately affects Alaska Native communities. Sitka Tribe of Alaska has organized an environmental monitoring program and seafood safety testing program along with other regional partners (called SEATOR: Southeast Alaska Tribal Ocean Research) to reduce the burden of PSP disease in Southeast Alaska. This grant seeks to augment SEATOR's ongoing efforts, through additional data collection and partnerships with the Sitka School District and Emory University. Collecting additional years of PSP toxin monitoring data using the same protocols as today will allow a time- series analysis to inform a cutting-edge forecasting model that will give Southeast Alaska residents warning of especially risky subsistence shellfish harvest times, and thereby prevent poisonings. Collecting new data on specific kinds of PSP toxins (rather than only measuring the presence or absence of any PSP toxin) can clarify which other settings around the world are most similar (e.g., by comparing toxin profiles). This is important because PSP is a global health problem and there are other locations that could benefit from an informative prediction model, or that might be able to provide useful information for developing this region's model. SEATOR will continue training members of the community via workshops on how to collect and process samples per the citizen science framework of the ongoing work. This project also includes planned K12 educational interventions to target PSP prevention messages to youth at particular risk of PSP toxicity, while also promoting science education and traditional lifeways. This project is fully community-based participatory research (CBPR) building on existing tribal organization programs, with employment and skills-training opportunities for members of the community, to meet community-prioritized needs and to address this health disparity.