Reinvigorating HIV Prevention and Care for People Who Use Drugs: Accelerating Progress and Sustaining Gains in the Midst of Societal Disruption

重振艾滋病毒预防和对吸毒者的护理：在社会混乱中加速进展并保持成果

• 批准号: 10528216
• 负责人: LINDA M COLLINS
• 金额: $ 43.89万
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-01 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10528216
• 关键词: AIDS prevention; Acceleration; Address; Affect; Area; Awareness; Behavioral; COVID-19 pandemic; Caring; Collaborations; Communicable Diseases; Communities; Complex; Consultations; Creativeness; Data; Disease Outbreaks; Disparity; Drug user; Epidemiology; Ethnography; Etiology; Evaluation; Event; Evidence based intervention; Formulation; Geography; Goals; HIV; Health; Human Resources; Individual; Inequity; Intervention; Intervention Studies; Lead; Longevity; Measurement; Methodology; Methods; Modeling; Pathway interactions; Personal Satisfaction; Population; Population Surveillance; Prevention; Process; Public Health; Quality of life; Research; Research Design; Research Methodology; Research Personnel; Research Project Grants; Research Support; Sampling; Testing; Time; Training; Work; behavioral and social science; biobehavior; community based participatory research; community engaged research; design; ethnic minority population; experience; health inequalities; implementation science; improved; innovation; member; minority communities; multidisciplinary; multiphase optimization strategy; novel; prevent; preventive intervention; racial minority population; resilience; social; social structure; success; theories; therapy design; transmission process; trend; uptake

Project Summary/Abstract – Transdisciplinary Research Methods Core The overarching goals of the Transdisciplinary Research Methods (TRM) Core are to (1) train and support our affiliated investigators in application of relevant research methods, including methods that may be new or complex, (2) make our investigators aware of innovative, cutting-edge methods that may be useful in their work and can open up possibilities that inspire new research questions, and (3) contribute to methodological advances. One primary area of emphasis will be on methods needed to understand the impacts of multilevel, time-varying processes and Big Events/BigTrends (BE/BT) on HIV prevention and care among PWUD. To support the work of a multidisciplinary set of investigators, we represent a range of expertise that includes field research and sampling; ethnography; infectious disease etiology, epidemiology and surveillance; community- engaged research; intervention design and testing, including optimization; and (now) designs and methods for causal inference, and the frameworks and methods of implementation science. This expertise is needed to understand how BE/BT impact the lives and health of PWUD, and to carry out research to develop interventions that will be relevant, resilient, and adaptable to societal changes. Building on prior successes, this Core will continue to focus on assisting affiliated investigators to integrate study design and methods with theories of prevention and care; create testable models of causal pathways; detect and respond to HIV outbreaks and other sequelae of BE/BT; and develop, test and implement potent and sustainable social, behavioral, and social-structural interventions. Specific Aims of the TRM core are: Aim 1. Lead the field and support CDUHR affiliated investigators in applying methods to enhance research conducted in the context of disruptions due to BE/BT by providing training, seminars, and consultation on quantitative, qualitative, and mixed methods, including the creative application and novel extensions of existing methods. Aim 2. Lead the field in the integration of the multiphase optimization strategy (MOST), implementation science (IS), and community-based participatory research (CBPR) methods, and build the capacity of CDUHR investigators to develop highly effective, efficient, implementable, and sustainable behavioral, biobehavioral, and social- structural interventions for prevention and treatment of HIV among PWUD by providing training and support in this area. Aim 3. Disseminate new research methods to the larger field, particularly methods relevant to responding to societal changes which may undermine or facilitate effective HIV prevention and care among PWUD.

项目摘要/摘要-跨学科研究方法核心 跨学科研究方法(TRM)核心的总体目标是：(1)培训和支持我们的 附属调查人员应用相关研究方法，包括可能是新的或 复杂，(2)使我们的调查人员了解创新的、尖端的方法，这些方法可能对他们的工作有用 并能开启激发新研究问题的可能性，以及(3)有助于方法论 预付款。一个主要的重点领域将是了解多层次的影响所需的方法， 关于残疾人中艾滋病毒预防和护理的时变过程和重大事件/大趋势(BE/BT)。至 支持多学科调查人员的工作，我们代表包括现场在内的一系列专业知识 研究和抽样；民族志；传染病病因学、流行病学和监测；社区-- 从事研究；干预设计和测试，包括优化；以及(现在)设计和方法 因果推理，以及实施科学的框架和方法。需要这种专业知识来 了解BE/BT如何影响PWUD的生活和健康，并开展研究以开发 干预措施将是相关的、有弹性的、能够适应社会变化的。在以往成功的基础上，这一次 CORE将继续专注于协助附属研究人员将研究设计和方法与 预防和护理理论；创建因果路径的可测试模型；检测和应对艾滋病毒 BE/Bt的暴发和其他后遗症；并制定、测试和实施有效和可持续的社会、 行为干预和社会结构干预。TRM核心的具体目标是：目标1.领导实地和 支持CDUHR附属调查员应用各种方法加强在以下背景下进行的研究 通过提供培训、研讨会和咨询来中断BE/BT 混合方法，包括对现有方法的创造性应用和新的扩展。目标2.领导 多阶段优化战略(MOST)、实施科学(IS)和 基于社区的参与性研究(CBPR)方法，并建设CDUHR调查人员的能力 制定高效、高效、可实施和可持续的行为、生物行为和社交- 通过在以下方面提供培训和支持，在残疾人中预防和治疗艾滋病毒的结构性干预措施 这片区域。目标3.向更大的领域传播新的研究方法，特别是与 应对可能破坏或促进有效预防和护理艾滋病毒的社会变化 PWUD。