Philadelphia Regional Center for Children’s Environmental Health

费城儿童环境健康区域中心（PRCCEH）是一个新的儿童中心。 这将提供基础设施，以整合宾夕法尼亚大学的CEH研究专业知识 佩雷尔曼医学院（PSOM），费城儿童医院（CHOP），德雷克塞尔大学，坦普尔 大学、托马斯杰斐逊大学、利哈伊大学、富兰克林和马歇尔学院、维拉诺瓦大学 和特拉华州大学合作，通过减少儿童早期的环境暴露来改善儿童的健康 在我们的区域。该中心将由主任丽贝卡西蒙斯，医学博士，和Aimin Chen，M.D.， 哲学博士、和副主任玛丽莲·豪沃思医学博士PRCCEH的使命是传播儿童的 环境卫生知识，卫生保健提供者，社区成员和决策者，发展， 测试和实施新的翻译产品，并让研究人员和社区合作伙伴参与进来， 政策、实践和行为改变，以减少生命早期的环境暴露。愿景和 PRCCEH的使命是面向费城地区，以解决紧迫的CEH问题。中心 由27名儿科、流行病学、职业和环境医学、毒理学、社会医学、 生态学、实施科学、社区参与、风险沟通、护理、生物信息学，以及 其他领域。该中心由一个行政核心和执行委员会、一个发展核心、 和翻译核心，并由内部咨询委员会和社区利益相关者咨询委员会提供建议 以马克思该中心将专注于四个主要研究和翻译领域：a）哮喘预防， 费城哮喘住院率的差异和社区哮喘预防计划 （CAPP）拥有20多年的经验; B）铅接触和危害减少，由差异驱动 在人口水平上，6岁以下儿童的血铅水平升高; c）空气污染， 费城-雷丁-卡姆登大都市统计区高年颗粒物和臭氧污染 （美国25个污染最严重的地区之一）;和d）内分泌干扰化学品， 通过增加EDC相关早产、肥胖和糖尿病以及神经发育的疾病负担， 紊乱中心成员在这些翻译领域经验丰富，并将实现以下目标 未来五年的具体目标。目标1。将PRCCEH建设成为CEH研究的区域基础设施中心 翻译：目标2扩大PRCCEH成员并利用机构资源促进CEH 翻译;目标3.在CEH研究中培养和指导早期研究者（ESI），并吸引建立 环境卫生（EH）科学家进入CEH;目标4。将CEH研究成果翻译给社区成员， 改善儿童健康;目标5。建立两个CEH翻译试点项目;目标6。 提供高效的行政服务，以促进研究翻译。

Philadelphia Regional Center for Children's Environmental Health (PRCCEH) is a new children's center which will provide the infrastructure to integrate CEH research expertise at University of Pennsylvania (Penn) Perelman School of Medicine (PSOM), Children's Hospital of Philadelphia (CHOP), Drexel University, Temple University, Thomas Jefferson University, Lehigh University, Franklin & Marshall College, Villanova University and University of Delaware to improve children's health by reducing environmental exposures in early life across our region. The Center will be led by Directors Rebecca Simmons, M.D., and Aimin Chen, M.D., Ph.D., and Deputy Director Marilyn Howarth, M.D. The mission of the PRCCEH is to disseminate children's environmental health knowledge to health care providers, community members, and policy makers, to develop, test and implement new translational products, and to engage researchers and community partners to make policy, practice, and behavioral changes to reduce environmental exposures in early life. The vision and the mission of the PRCCEH are oriented to the Philadelphia region to address pressing CEH issues. The Center consists of 27 experts in pediatrics, epidemiology, occupational and environmental medicine, toxicology, social ecology, implementation science, community engagement, risk communication, nursing, bioinformatics, and other areas. The Center is comprised of an Administrative Core and Executive Committee, a Development Core, and a Translation Core, and is advised by Internal Advisory Committee and Community Stakeholder Advisory Committee. The Center will focus on four primary research and translation areas: a) Asthma prevention, motivated by disparity of asthma hospitalization in Philadelphia and a Community Asthma Prevention Program (CAPP) with more than 20 years of experience; b) Lead exposure and harm reduction, motivated by a disparity in elevated blood lead levels in children <6 years of age at the population level; c) Air pollution, motivated by high annual particulate matter and ozone pollution in Philadelphia-Reading-Camden Metropolitan Statistical Area (among the 25 worst polluted areas in the U.S.); and d) Endocrine disrupting chemicals (EDCs), motivated by increasing disease burden from EDC-related preterm birth, obesity and diabetes, and neurodevelopmental disorders. The Center members are experienced in these translational areas and will achieve the following Specific Aims in the next 5 years. Aim 1. Build the PRCCEH as a regional infrastructure center for CEH research and translation; Aim 2. Expand PRCCEH membership and leverage institutional resources to promote CEH translation; Aim 3. Nurture and mentor early stage investigators (ESI) in CEH research and attract established environmental health (EH) scientists into CEH; Aim 4. Translate CEH research to community members and stakeholders to improve children's health; Aim 5. Establish two pilot programs for CEH translation; Aim 6. Provide efficient administrative services to facilitate research translation.