Philadelphia Regional Center for Children’s Environmental Health

费城地区儿童环境健康中心(PRCCEH)是一个新的儿童中心 这将为整合宾夕法尼亚大学(宾夕法尼亚大学)CEH研究专业知识提供基础设施 佩雷尔曼医学院(PSOM)，费城儿童医院(CHOP)，德雷塞尔大学，坦普尔 大学、托马斯·杰斐逊大学、利哈伊大学、富兰克林和马歇尔学院、维拉诺瓦大学 和特拉华大学通过减少儿童早期接触环境来改善儿童健康 在我们整个地区。该中心将由医学博士丽贝卡·西蒙斯和医学博士陈爱民领导， 医学博士和副主任Marilyn Howarth医学博士。PRCCEH的使命是传播儿童的 向卫生保健提供者、社区成员和政策制定者提供环境健康知识，以发展、 测试和实施新的翻译产品，并让研究人员和社区合作伙伴参与 政策、实践和行为改变，以减少早期生活中的环境暴露。这一愿景和 PRCCEH的使命定位于费城地区，以解决紧迫的CEH问题。《中心》 由27名儿科、流行病学、职业和环境医学、毒理学、社会医学专家组成 生态学、实施科学、社区参与、风险沟通、护理、生物信息学和 其他领域。该中心由行政核心和执行委员会、发展核心、 和翻译核心，由内部咨询委员会和社区利益攸关方咨询提供咨询 委员会审议阶段。该中心将专注于四个主要研究和翻译领域：a)哮喘预防， 费城哮喘住院差异和社区哮喘预防计划的激励 (CAPP)有20多年的经验；b)铅暴露和减少危害，受差异驱动 在人口层面上，6岁儿童血铅水平升高；c)空气污染，由 费城-雷丁-卡姆登大都会统计区年高颗粒物和臭氧污染 (美国污染最严重的25个地区之一)；和d)内分泌干扰物(EDCs)，动机 通过增加EDC相关早产、肥胖和糖尿病以及神经发育造成的疾病负担 精神错乱。中心成员在这些翻译领域经验丰富，将实现以下目标 未来5年的具体目标。目标1.将环卫中心建设为环卫研究的区域基础设施中心 和翻译；目标2.扩大PRCCEH成员并利用机构资源促进CEH 翻译；目标3.培养和指导CEH研究的早期调查人员(ESI)，并吸引已建立的 将环境健康(EH)科学家转化为CEH；目标4.将CEH研究转化为社区成员和 利益攸关方改善儿童健康；目标5。建立CEH翻译的两个试点项目；目标6。 提供高效的行政服务，促进科研翻译。

Philadelphia Regional Center for Children's Environmental Health (PRCCEH) is a new children's center which will provide the infrastructure to integrate CEH research expertise at University of Pennsylvania (Penn) Perelman School of Medicine (PSOM), Children's Hospital of Philadelphia (CHOP), Drexel University, Temple University, Thomas Jefferson University, Lehigh University, Franklin & Marshall College, Villanova University and University of Delaware to improve children's health by reducing environmental exposures in early life across our region. The Center will be led by Directors Rebecca Simmons, M.D., and Aimin Chen, M.D., Ph.D., and Deputy Director Marilyn Howarth, M.D. The mission of the PRCCEH is to disseminate children's environmental health knowledge to health care providers, community members, and policy makers, to develop, test and implement new translational products, and to engage researchers and community partners to make policy, practice, and behavioral changes to reduce environmental exposures in early life. The vision and the mission of the PRCCEH are oriented to the Philadelphia region to address pressing CEH issues. The Center consists of 27 experts in pediatrics, epidemiology, occupational and environmental medicine, toxicology, social ecology, implementation science, community engagement, risk communication, nursing, bioinformatics, and other areas. The Center is comprised of an Administrative Core and Executive Committee, a Development Core, and a Translation Core, and is advised by Internal Advisory Committee and Community Stakeholder Advisory Committee. The Center will focus on four primary research and translation areas: a) Asthma prevention, motivated by disparity of asthma hospitalization in Philadelphia and a Community Asthma Prevention Program (CAPP) with more than 20 years of experience; b) Lead exposure and harm reduction, motivated by a disparity in elevated blood lead levels in children <6 years of age at the population level; c) Air pollution, motivated by high annual particulate matter and ozone pollution in Philadelphia-Reading-Camden Metropolitan Statistical Area (among the 25 worst polluted areas in the U.S.); and d) Endocrine disrupting chemicals (EDCs), motivated by increasing disease burden from EDC-related preterm birth, obesity and diabetes, and neurodevelopmental disorders. The Center members are experienced in these translational areas and will achieve the following Specific Aims in the next 5 years. Aim 1. Build the PRCCEH as a regional infrastructure center for CEH research and translation; Aim 2. Expand PRCCEH membership and leverage institutional resources to promote CEH translation; Aim 3. Nurture and mentor early stage investigators (ESI) in CEH research and attract established environmental health (EH) scientists into CEH; Aim 4. Translate CEH research to community members and stakeholders to improve children's health; Aim 5. Establish two pilot programs for CEH translation; Aim 6. Provide efficient administrative services to facilitate research translation.