RR&D Research Career Scientist Award Application

RR

• 批准号: 10554101
• 负责人: ALICE S. RYAN
• 金额: --
• 依托单位: BALTIMORE VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2029-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10554101
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My research focuses on developing and testing interventions to restore function and minimize disability following acute disabling events and to prevent declines related to serious chronic diseases. In addition, my work aims to advance our understanding of the mechanisms by which exercise and rehabilitation interventions directed at specific impairments affect body systems and tissues. My passion is also to train the next generation of investigators who will further the understanding of the aging process and develop interventions that help promote health and independence in older adults with disabling medical conditions. My work aligns well with the mission of Rehabilitation Research & Development (RR&D) and renewal of this Senior Research Career Scientist Award will allow me to continue this path. My entire career has been within the VA Maryland Health Care System with my first VA Merit awarded in 2001 Clinical Science Research & Development (CSR&D) and appointment as a VA Research Scientist, receipt of a NIH RO1 in 2001, and award of the Research Career Scientist (RCS) within CSR&D in 2004. During the first 5-years of the RCS, I was awarded a second VA Merit (CSR&D), a second NIH/RO1, and played an integral role in the receipt of three center grants where I was PI or co-investigator on research cores. During years 5-10 of the RCS, I obtained a third VA Merit (RR&D), a Merit Pilot Award (RR&D), was a co-investigator on four VA Merit Awards (CSR&D and RR&D), five NIH RO1 grants, two NIH-R awards, and led cores in three center grants. I was awarded a fourth VA Merit (RR&D) in 2015. During the SRCS which began in 2015, I was awarded a VA SPiRE (RR&D) in 2018, and fifth and sixth VA Merit Awards in 2019 and 2020 in RR&D and CSR&D, respectively. I was also awarded or a co-investigator on multiple NIH projects during this past cycle. I will be MPI in the renewal of the University of Maryland (UM) Claude D. Pepper Older Americans Independence Center (OAIC). My research career has thrived in this enriched research environment in collaboration with Veterans Affairs and University of Maryland M.D. and Ph.D. investigators. My leadership, independence, collegial attitude and collaborative nature serve to promote innovative patient-oriented research in preventive medicine, exercise rehabilitation, nutrition and aging in the VA Research Service, Baltimore GRECC, UM-OAIC, the Division of Gerontology and Palliative Medicine and in the past for the VA RR&D Center of Excellence, Exercise and Robotics in Neurological Disease and the Mid-Atlantic Nutrition and Obesity Research Center. I have enjoyed more recent opportunities to conduct multi-site clinical trials which further strengthen and expand the science in our goals to maximize independence in aging Veterans. I hold leadership positions within the Geriatrics, Research, Education & Clinical Centers (GRECC), have been a long-standing member of local VA committees (R&D and SRS), am a 13-year member of the Medicine Appointment, Promotions, Tenure (APT) Committee at UM, and have a continuous track record as member and chair of VA and NIH review panels. In my leadership positions, I promote and assist investigators in combined exercise and rehabilitation medicine interventions to examine changes in the cardiovascular and musculoskeletal systems and the link to function and mobility. Further, I have a successful history of training of junior scientists in becoming independent academic careers in exercise and rehabilitation science as a primary mentor of numerous postdoctoral fellows and upon receipt of their VA CDA or NIH K-Award. My commitment and joy in mentoring medical students, fellows and junior investigators in rehabilitation research continues to grow. I am indeed fortunate to have collaborators which cross so many disciplines including gerontology, exercise physiology, infectious disease, neurology, oncology, physical therapy, vascular surgery, radiology, pulmonology, and rheumatology. I am honored to have received the Senior Research Career Scientist and greatly appreciate the opportunity to renew this prestigious award.

我的研究重点是开发和测试干预措施，以恢复功能和尽量减少残疾 在发生急性致残事件后，并防止与严重慢性疾病有关的衰退。此外，我的工作 旨在促进我们对运动和康复干预机制的理解， 针对影响身体系统和组织的特定损伤。我的热情也是为了培养下一代 研究人员将进一步了解衰老过程，并制定干预措施， 促进有残疾医疗条件的老年人的健康和独立。我的工作与 康复研究与发展（RR&D）的使命和这一高级研究职业的更新 科学家奖将让我继续这条道路。 我的整个职业生涯一直在弗吉尼亚州马里兰州卫生保健系统与我的第一个VA的优点授予 2001年临床科学研究与开发（CSR&D）并被任命为VA研究科学家，收到 2001年获得NIH RO 1，2004年获得CSR&D内的研究职业科学家（RCS）奖。期间 在RCS的前5年，我被授予第二个VA Merit（CSR&D），第二个NIH/RO 1，并发挥了积分 在三个中心的赠款，我是PI或研究核心的共同研究者接收的作用。5-10年期间 在RCS中，我获得了第三个VA Merit（RR&D），一个Merit Pilot Award（RR&D），是四个VA的共同研究员 优异奖（CSR&D和RR&D），五个NIH RO 1赠款，两个NIH-R奖，以及三个中心赠款的领导核心。 我在2015年获得了第四次VA Merit（RR&D）。在2015年开始的SRCS期间，我被授予VA 2018年SPiRE（RR&D），以及2019年和2020年RR&D和CSR&D的第五和第六届VA优异奖， 分别在过去的一个周期中，我还被授予或担任多个NIH项目的共同研究者。我将成为MPI 在马里兰州（UM）的更新克劳德D。佩珀老年美国人独立中心 （审咨委）。我的研究生涯在这个丰富的研究环境中与退伍军人合作蓬勃发展 事务和马里兰州大学医学博士。和博士investigators.我的领导能力，独立性，学院式的态度 和协作的性质，以促进创新的病人为导向的研究，在预防医学，运动 康复，营养和老龄化的VA研究服务，巴尔的摩GRECC，UM-OAIC， 老年学和姑息医学，并在过去的VA RR&D卓越中心，运动和 神经系统疾病中的机器人和大西洋中部营养与肥胖研究中心。我已经享受 最近有机会进行多中心临床试验，进一步加强和扩大科学， 我们的目标是最大限度地提高老年退伍军人的独立性。 我在老年医学、研究、教育和临床中心（GRECC）担任领导职务， 我是当地退伍军人事务委员会（研发和SRS）的长期成员，我是医学委员会的13年成员 任命，晋升，任期（APT）委员会在UM，并有连续的跟踪记录， VA和NIH审查小组主席。在我的领导职位上，我促进和协助调查人员， 运动和康复医学干预，以检查心血管和肌肉骨骼的变化 系统以及与功能和移动性的联系。此外，我在培训初级科学家方面有着成功的历史， 在成为独立的学术生涯，在运动和康复科学的主要导师， 许多博士后研究员，并在收到他们的VA CDA或NIH K奖。我的承诺和喜悦 在康复研究中指导医学生、研究员和初级研究员的工作继续增加。 我确实很幸运有这么多跨学科的合作者，包括老年学， 运动生理学，传染病，神经病学，肿瘤学，物理治疗，血管外科，放射学， 肺病学和风湿病学。我很荣幸能接待高级研究职业科学家， 非常感谢有机会再次获得这一著名奖项。