Core A: Administrative and Enrollment Core

核心 A：行政和招生核心

• 批准号: 10555690
• 负责人: LI-SAN WANG
• 金额: $ 517.14万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10555690
• 关键词: Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Asian; Asian Americans; Benchmarking; Biological Markers; Budgets; Canada; Collaborations; Communities; Complex; Consent Forms; Data; Data Analyses; Data Set; Dementia; Development; Electronic Mail; Enrollment; Ensure; FAIR principles; Freezing; Funding Agency; Future; Genetic; Genetic Diseases; Genetic study; Genotype; Human Subject Research; Institutional Review Boards; Leadership; National Institute on Aging; Participant; Performance; Persons; Phenotype; Progress Reports; Protocols documentation; Publications; Qualifying; Recruitment Activity; Recurrence; Research; Research Personnel; Research Project Grants; Resources; SNP array; Sampling; Schedule; Science; Site; Standardization; Structure; Training; Training Activity; Transfer Agreement; Update; Work; cohort; data access; data exchange; data harmonization; data management; data sharing; dementia risk; functional genomics; genome sequencing; genome wide association study; genome-wide; genomic data; interest; meetings; non-genetic; outreach; phenotypic data; programs; quality assurance; recruit; repository; response; symposium; web site; whole genome

Administrative and Enrollment Core (Core A) Abstract The Administrative and Enrollment Core (Core A) is mandated by the PAR and will oversee, facilitate and coordinate all ACAD activities carried out by other Cores and Projects. Using a robust administrative structure, the Core directs the ACAD’s activities to ensure maximal coordination and produce cutting-edge science to support the ACAD project. Core A will identify relevant ADRD data sets (ADGC, ADSP and non-ADSP data), and coordinate acquisition, processing, and harmonization of these data with the Data Management and Analysis Core (Core D) and Projects. Data will include: 1) genetic data (GWAS SNP array data), 2) biomarker and functional genomics (FG) data, and 3) phenotype data from ACAD participants and other non-ACAD datasets. Core A will coordinate transfer of ACAD data and analysis results to National Institute on Aging Genetics of Alzheimer’s Disease Storage site (NIAGADS) for sharing with the general scientific community.

行政和招生核心（核心A）摘要 行政和注册核心（核心A）是由PAR授权，并将监督，促进和 协调其他核心和项目开展的所有ACAD活动。利用强有力的行政结构， 核心指导ACAD的活动，以确保最大限度的协调和产生尖端科学， 支持ACAD项目。核心A将确定相关ADRD数据集（ADGC、ADSP和非ADSP数据）， 并与数据管理部门协调这些数据的采集、处理和协调， 分析核心（核心D）和项目。数据将包括：1）遗传数据（GWAS SNP阵列数据），2）生物标志物 和功能基因组学（FG）数据，以及3）来自ACAD参与者和其他非ACAD参与者的表型数据。 数据集。核心A将协调将ACAD数据和分析结果转移到国家老龄研究所 阿尔茨海默病遗传学存储网站（NIAGADS）与一般科学界分享。