A Multi-Optrode Array for Closed-Loop Bionics

用于闭环仿生学的多光极阵列

• 批准号: DP200102825
• 负责人: Prof Nigel Lovell
• 金额: $ 34.78万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2023-12-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200102825
• 关键词: Multi; Optrode; Array; Closed; Loop

We will design, implement and characterise a disruptive multi-channel optrode array (MOA) to record and stimulate excitable living tissue. The MOA will be a combination of individual optical electrodes (optrodes) that either comprise a new class of liquid crystals, used to passively sense extracellular biopotentials, or microphotovoltaic cells that will be used for electrical stimulation of excitable tissue. By employing light for communication with optrodes, this new approach alleviates many of the wiring, packaging and encapsulation issues associated with existing devices. Computational modelling and in vitro testing in cardiac tissue and retinal neurons will demonstrate the utility of the MOA to sense and control electrical activity.

我们将设计、实现和组装一个破坏性的多通道光极阵列（MOA）来记录和刺激可兴奋的活组织。MOA将是单独的光学电极（光极）的组合，其包括用于被动地感测细胞外生物电势的新型液晶，或将用于可兴奋组织的电刺激的微光伏电池。通过采用光与光极通信，这种新方法解决了与现有器件相关的许多布线、封装和封装问题。在心脏组织和视网膜神经元中的计算建模和体外测试将证明MOA用于感测和控制电活动的实用性。