NEW INSTRUMENT FOR GENERATING COMBINATORIAL LIBRARIES

用于生成组合库的新工具

• 批准号: 2190396
• 负责人: GARY M NISHIOKA
• 金额: $ 7.5万
• 依托单位: H AND N INSTRUMENTS, INC.
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-15 至 1995-05-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2190396
• 关键词: antiantibody; antibody; biomedical automation; biomedical equipment development; fluorescence microscopy; gamma aminobutyrate; peptide chemical synthesis; peptides

The development of a new instrument for synthesizing combinatorial libraries is proposed. The instrument, coined SCAMP, has the potential to synthesize peptide arrays containing millions of related peptides. It will be highly automated, and thus find use by those unskilled in the use of combinatorial libraries. It has the further potential of being relatively inexpensive, and thus readily available to most researchers. The objective of Phase I is to demonstrate the ability of SCAMP to synthesize peptides in a spatially well-defined array. The ultimate goal of this research is to develop a highly automated, user-friendly instrument for synthesizing large combinatorial arrays.

一种新型组合式合成仪的研制 图书馆提出。该仪器被称为SCAMP，有可能 合成含有数百万个相关肽的肽阵列。它将 高度自动化，因此可以被那些不熟练的人使用， 组合库它还有一个潜力， 价格低廉，因此对大多数研究人员来说都很容易获得。 第一阶段的目标是证明SCAMP的能力， 以空间上明确限定阵列合成肽。最终目标 这项研究的目的是开发一个高度自动化，用户友好的 用于合成大型组合阵列的仪器。