STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
批准号:
2173547
负责人:
ALFRED Guillou REDFIELD
金额:
$21.28万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1976
资助国家:
美国
项目状态:
已结题
起止时间:
1976-06-01 至 1996-07-31
中文摘要
核磁共振光谱学将继续应用于确定结构和
英文摘要
NMR Spectroscopy will continue to be applied to determine the structure and
dynamics of transfer RNA in interaction with the enzyme aminoacyl tRNA
synthetase. These two macromolecules are essential parts of the
biosynthetic machinery of all living things. The emphasis is on use of
isotope labels of 15N and 13C to highlight proton NMR signals and provide
more information than straight NMR spectroscopy. Smaller molecules
interacting with the enzyme, as well as labelled enzyme and labelled tRNA,
will be examined to provide information on molecular changes during
function of the molecules. The NMR methods being used are prototypical of
methods potentially applicable to drug design.
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Use of 13C and 15N isotope labels for proton nuclear magnetic resonance and nuclear Overhauser effect. Structural and dynamic studies of larger proteins and nucleic acids.
使用 13C 和 15N 同位素标记进行质子核磁共振和核奥沃豪塞效应。
DOI:
--
发表时间:
1989
期刊:
Archivos de biologia y medicina experimentales
影响因子:
--
作者:
[Redfield,AG, McIntosh,LP, Dahlquist,FW]
通讯作者:
Dahlquist,FW
Proton exchange rates in transfer RNA as a function of spermidine and magnesium.
转移 RNA 中的质子交换率与亚精胺和镁的函数关系。
DOI:
10.1093/nar/11.7.2121
发表时间:
1983
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Tropp,JS, Redfield,AG]
通讯作者:
Redfield,AG
Proton NMR and NOE structural and dynamic studies of larger proteins and nucleic acids aided by isotope labels: T4 lysozyme.
借助同位素标记:T4 溶菌酶,对较大蛋白质和核酸进行质子 NMR 和 NOE 结构和动态研究。
DOI:
10.1080/07391102.1987.10506372
发表时间:
1987
期刊:
Journal of biomolecular structure & dynamics
影响因子:
4.4
作者:
[McIntosh,LP, Dahlquist,FW, Redfield,AG]
通讯作者:
Redfield,AG
Kinetics of proton exchange of phosphatidylethanolamine in phospholipid vesicles.
磷脂囊泡中磷脂酰乙醇胺的质子交换动力学。
DOI:
10.1016/s0006-3495(85)83868-6
发表时间:
1985
期刊:
Biophysical journal
影响因子:
3.4
作者:
[Ralph,EK, Lange,Y, Redfield,AG]
通讯作者:
Redfield,AG
NMR study of isoleucine transfer RNA from Thermus thermophilus.
嗜热栖热菌异亮氨酸转移 RNA 的 NMR 研究。
DOI:
10.1021/bi00355a010
发表时间:
1986
期刊:
Biochemistry
影响因子:
2.9
作者:
[Choi,BS, Redfield,AG]
通讯作者:
Redfield,AG
共 19 条
Applications of Field-Cycling NMR to Studies of Biomolecules.
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批准号:6963056
-
项目类别:
-
资助金额:$15.4万
-
财政年份:2005
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
Applications of Field-Cycling NMR to Studies of Biomolecules
-
批准号:7283043
-
项目类别:
-
资助金额:$14.6万
-
财政年份:2005
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
Applications of Field-Cycling NMR to Studies of Biomolecules.
-
批准号:7124729
-
项目类别:
-
资助金额:$15.04万
-
财政年份:2005
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
Applications of Field-Cycling NMR to Studies of Biomolecules
-
批准号:7493388
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项目类别:
-
资助金额:$14.6万
-
财政年份:2005
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURE OF RAC I PROTEIN: A RAS-LIKE SMALL G PROTEIN
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批准号:6279678
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项目类别:
-
资助金额:$2.01万
-
财政年份:1998
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
CONFERENCE MAGNETIC RESONANCE IN BIOLOGICAL SYSTEMS
-
批准号:3435100
-
项目类别:
-
资助金额:$1.7万
-
财政年份:1990
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负责人:ALFRED Guillou REDFIELD
-
依托单位:
HIGH FIELD NMR SPECTROMETER FOR CHEMISTRY & BIOCHEMISTRY
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批准号:3520830
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项目类别:
-
资助金额:$40.0万
-
财政年份:1990
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:2749776
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项目类别:
-
资助金额:$24.27万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
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批准号:3484348
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项目类别:
-
资助金额:$18.18万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:3269919
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项目类别:
-
资助金额:$19.51万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:2173546
-
项目类别:
-
资助金额:$19.75万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:2173548
-
项目类别:
-
资助金额:$24.72万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:3484346
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项目类别:
-
资助金额:$21.8万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:3484344
-
项目类别:
-
资助金额:$20.29万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:3484345
-
项目类别:
-
资助金额:$20.61万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:3484342
-
项目类别:
-
资助金额:$18.68万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:3484343
-
项目类别:
-
资助金额:$20.09万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:6018449
-
项目类别:
-
资助金额:$25.22万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:3484349
-
项目类别:
-
资助金额:$18.9万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位:
STRUCTURAL KINETIC STUDIES BY NUCLEAR MAGNETIC RESONANCE
-
批准号:2459308
-
项目类别:
-
资助金额:$24.07万
-
财政年份:1976
-
负责人:ALFRED Guillou REDFIELD
-
依托单位: