EPIDEMIOLOGY & PREVENTION OF ALCOHOL ABUSE & ALCOHOLISM

研究计划包括四个项目： 1)扩大和加强持续的流行病学方案和 教育与教育之间可疑因果关系的预防研究 在酗酒和依赖方面的成就和发展 非裔美国人。这一拟议项目将需要进行二次分析。 流行病集水区调查以及其他社区- 基于数据集。 2)评估饮酒与教育的关系 通过分析来自社区的数据在青少年中取得的成就 巴尔的摩市小学生研究。这个项目将 提供有关学校成绩的时间关联的信息 与饮酒的开始，以及酒与人的关系 将启动与将启动转换为问题的步骤一起使用 青春期饮酒。 3)研究饮酒和饮酒问题的家族决定因素 通过对正在进行的研究实施病例队列研究，在青少年中进行 在巴尔的摩市小学开始酗酒和吸毒 在校学生。这个项目将包括对家庭的采访 获取有关酒精、非法药物家族史的信息 使用和精神障碍。 4)开发并提交RO1申请，以启动预防或 在本裁决的最后阶段进行的早期干预试验 早期项目的结果。对公众健康的重要性 拟议的研究计划在一定程度上取决于确定 酒精紊乱风险增加的群体。尤其是，因为 教育是一个潜在的可修改的特征，结果应该是 增加必要的知识库，以建立更好的预防和 最终可能降低患病率的改善性干预措施 酗酒或酒精依赖。

The research plan includes four projects: 1) To extend and strengthen a continuing program of epidemiology and prevention research on suspected causal associations between educational achievement and the development of alcohol abuse and dependence among Afro-Americans. This proposed project would entail secondary analyses of the Epidemiologic Catchment Area surveys as well as other community- based datasets. 2) To evaluate the relationship of alcohol use with educational achievement among adolescents by analyzing data from a community based study of Baltimore city elementary school children. this project would provide information on the temporal association of school achievement with the initiation of alcohol use, and on the relationship of alcohol use initiation with the steps that translate that initiation to problem drinking in adolescence. 3) To examine familial determinants of alcohol use and problem drinking among adolescents by implementing a case-cohort study to an ongoing study of the initiation of alcohol and drug use among Baltimore City elementary school children. This project would incorporate interviews of families to elicit information regarding family history of alcohol, illicit drug use and psychiatric disorders. 4) To develop and submit an RO1 application to initiate a prevention or early intervention trial in the final stages of this award based ont he findings of the earlier projects. The public health importance of the proposed research plan rests in part upon possibilities for identifying groups at increased risk of alcohol disorders. In particular, because education is a potentially modifiable characteristic, the results should increase the knowledge base necessary to build better preventive and ameliorative interventions that ultimately might reduce the prevalence of alcohol abuse or alcohol dependence.