EPIDEMIOLOGY & PREVENTION OF ALCOHOL ABUSE & ALCOHOLISM

研究计划包括四个项目： 1)扩大和加强流行病学的持续方案， 预防研究怀疑因果关系之间的教育 酒精滥用和依赖问题的进展情况 非裔美国人 这一拟议项目将需要进行二次分析 流行病学集水区调查以及其他社区- 基于数据集。 2)评估饮酒与教育的关系 通过分析来自社区的数据， 对巴尔的摩市小学儿童的研究。 这个项目将 提供关于学校成绩与 与酒精使用的关系，以及酒精与 使用启动的步骤，将启动转化为问题 青春期喝酒 3)研究酒精使用和问题饮酒的家庭决定因素 通过对正在进行的研究实施病例队列研究，在青少年中进行 在巴尔的摩市的小学生中， 学生。 该项目将包括对家庭的采访 以了解家族酗酒史，非法药物 使用和精神疾病。 4)制定并提交RO 1申请，以启动预防或 在本裁决的最后阶段， 早期项目的发现。 公共卫生的重要性 拟议的研究计划部分取决于确定 酒精障碍风险增加的群体。 尤其是因为 教育是一个潜在的可改变的特征，结果应该 增加必要的知识基础，以建立更好的预防和 最终可能降低患病率的改善干预措施 酒精滥用或酒精依赖。

The research plan includes four projects: 1) To extend and strengthen a continuing program of epidemiology and prevention research on suspected causal associations between educational achievement and the development of alcohol abuse and dependence among Afro-Americans. This proposed project would entail secondary analyses of the Epidemiologic Catchment Area surveys as well as other community- based datasets. 2) To evaluate the relationship of alcohol use with educational achievement among adolescents by analyzing data from a community based study of Baltimore city elementary school children. this project would provide information on the temporal association of school achievement with the initiation of alcohol use, and on the relationship of alcohol use initiation with the steps that translate that initiation to problem drinking in adolescence. 3) To examine familial determinants of alcohol use and problem drinking among adolescents by implementing a case-cohort study to an ongoing study of the initiation of alcohol and drug use among Baltimore City elementary school children. This project would incorporate interviews of families to elicit information regarding family history of alcohol, illicit drug use and psychiatric disorders. 4) To develop and submit an RO1 application to initiate a prevention or early intervention trial in the final stages of this award based ont he findings of the earlier projects. The public health importance of the proposed research plan rests in part upon possibilities for identifying groups at increased risk of alcohol disorders. In particular, because education is a potentially modifiable characteristic, the results should increase the knowledge base necessary to build better preventive and ameliorative interventions that ultimately might reduce the prevalence of alcohol abuse or alcohol dependence.