ORAL RESPIRATORY COORDINATION IN PRETERM INFANTS

早产儿的口腔呼吸协调

• 批准号: 2203493
• 负责人: EUGENE C GOLDFIELD
• 金额: $ 16.31万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-08-01 至 1997-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2203493
• 关键词: behavior test; body movement; body physical characteristic; child (0-11); child behavior; circadian rhythms; cryings; developmental neurobiology; human subject; longitudinal human study; low birth weight infant human; neuromuscular function; neuropsychological tests; oral behavior; premature infant human; pulmonary respiration; sleep; temporal lobe /cortex; vocalization; wakefulness

The effects of prematurity on the developing nervous system remain unclear, in part because current methods of neonatal neuromotor assessment do not include measures of timing and coordination, and because prediction from neonatal to later behavior does not specify how early components of later acquired skills become coordinated in new ways during development. The need for sensitive measures of timing in infant neuromotor assessment is evident in the development of speech production, where the timing of breathing and oral movements is critical. While it is well established that disorders of speech production are associated with prematurity, it is not known whether these disorders are related to the timing of component motor rhythm (e.g., mouth movements evident in sucking, respiratory movement of chest and abdomen) or to the process by which breathing and oral motor rhythms interact. This study examines both the timing of early motor rhythms (respiration, non-nutritive and nutritive sucking, crying) and their relation to the development of non-cry vocalizations during the first year. A group of high risk preterm infants is contrasted with healthy preterm and full term groups. Oral and respiratory motor rhythms and non-cry vocalizations are recorded longitudinally during the first year, along with standardized assessment of mental and motor development. The direct measurement of the timing of sucking and respiration and their interaction is combined with an analysis of the effects of minor perturbation on timing as quantitative measures of the influences of prematurity on the developing nervous system. The quantitative measures of the influences of prematurity on the developing nervous system. The quantitative timing measures are also used to predict characteristics of timing in breath groups and consonant production during non-cry vocalizations in the first year.

早产对发育中的神经系统的影响仍然存在 不清楚，部分原因是目前新生儿神经运动的方法 评估不包括时间和协调措施， 因为从新生儿到后期行为的预测并没有说明如何 后来获得的技能的早期组成部分以新的方式协调起来 在发展过程中。 婴儿需要敏感的时间测量 神经运动评估在言语产生的发展中是明显的， 其中呼吸和口腔运动的时机是关键的。 虽然 公认的是，言语产生障碍与 对于早产，尚不清楚这些疾病是否与 分量运动节律的定时（例如，嘴部动作明显， 吸吮，胸部和腹部的呼吸运动）或通过 呼吸和口腔运动节奏相互作用。 这项研究检查了早期运动节律（呼吸， 非营养性和营养性吸吮，哭泣）及其与 在第一年发展出不哭的声音。 一群 高风险早产儿与健康早产儿和足月儿相比， 术语组。 口腔和呼吸运动节律和不哭 发声记录纵向在第一年，沿着 对智力和运动发育进行标准化评估 直接 测量吸吮和呼吸的时间及其 相互作用与分析的影响，小 作为影响的定量测量的时间扰动 对神经系统发育的影响 的定量量度 早产对神经系统发育的影响。 的 定量的时间测量也被用来预测 呼吸组的时间和不哭时的辅音产生 第一年的发音。