Be(e) friendly venomous spiders! Novel biopesticides from arachnid venoms

是友好的毒蜘蛛！

• 批准号: FT190100482
• 负责人: A/Prof Volker Herzig
• 金额: $ 53.13万
• 依托单位: University of the Sunshine Coast
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT190100482
• 关键词: friendly; venomous; spiders; Novel; biopesticides

The overall aim of this project is to improve global honeybee health by developing novel bee-friendly bioinsecticides as well as treatments against honeybee parasites such as varroa mites and small hive beetles. This project seeks to significantly improve existing insecticidal lead peptides from spider venoms to increase their oral toxicity and make them more pest-specific. Expected outcomes of this project include a panel of biologically degradable venom peptides that are active against selected pest and parasite species and that can be economically produced in large scale. This would not only provide significant environmental, social and economical benefits on a global scale, but also boost the Australian agrochemical research sector.

该项目的总体目标是通过开发新型蜜蜂友好型生物杀虫剂以及治疗蜜蜂寄生虫（如瓦螨和小蜂巢甲虫）来改善全球蜜蜂健康。该项目旨在显着改善现有的蜘蛛毒液中的杀虫先导肽，以增加其口服毒性，并使其更具害虫特异性。该项目的预期成果包括一组可生物降解的毒液肽，这些毒液肽对选定的害虫和寄生虫物种具有活性，并且可以大规模经济地生产。这不仅将在全球范围内带来重大的环境、社会和经济效益，还将推动澳大利亚农业化学研究部门的发展。