SOUTHWEST ONCOLOGY GROUP--STATISTICAL CENTER

西南肿瘤集团--统计中心

• 批准号: 2007481
• 负责人: JOHN J CROWLEY
• 金额: $ 328.7万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-01-01 至 1997-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2007481
• 关键词: cancer information system; cancer prevention; cancer registry /resource; clinical trials; computer center; cooperative study; data collection; human subject; human therapy evaluation; neoplasm /cancer epidemiology; online computer; prognosis; publications; statistical service /center; technology /technique development

The Southwest Oncology Group is a major multi-disease, multi- disciplinary, multi-institution group engaged in cooperative cancer research. This organization now consists of 34 Member Institutions, 26 Community Clinical Oncology Programs (CCOPs), 291 Cooperative Group outreach Programs (CGOPs), 23 Urologic Cancer Outreach Programs (UCOPs) and 26 High Priority affiliates, who accrue approximately 8700 patients to clinical trials each year. Currently there are approximately 100 studies open for accrual in 14 committees. The Statistical Center is essential to the design, conduct, and analysis of the cancer research in the Southwest oncology Group. Its main functions are: to participate in the review of proposed protocols, particularly as regards experimental design, sample size, and feasibility; to provide for central registration of all patients on all studies, and for randomization where appropriate; to provide for review and quality control of data collected during studies; to provide for data entry and for computer processing, storage and retrieval of data; to work with the Group chair and other investigators in the Group to improve the quality of clinical trials through improved forms, more uniform and reproducible data definitions, and more economical flow of data; to help the Group chair in the administration of the Group; to analyze and publish the results of studies in conjunction with the study coordinator; to use the data being collected to try to find new leads regarding prognostic factors and late effects; and to perform statistical research on the efficient design, conduct and analysis of cancer clinical trials and cancer control research.

西南肿瘤学组是一个多病种、多学科的大 从事癌症合作的学科、多机构小组 研究。 该组织现拥有 34 个成员机构、26 个 社区临床肿瘤学计划 (CCOP)，291 合作组 外展计划 (CGOP)、23 个泌尿系统癌症外展计划 (UCOP) 和 26 个高优先级附属机构，吸引了大约 8700 名患者 每年进行临床试验。 目前大约有100个 研究成果在 14 个委员会开放供累积。 统计中心是 对于癌症研究的设计、实施和分析至关重要 西南肿瘤学组。 其主要职能是：参与 对拟议方案的审查，特别是实验性方案的审查 设计、样本大小和可行性；提供中央登记 所有研究中的所有患者，并在适当情况下进行随机化； 对期间收集的数据进行审查和质量控制 研究；提供数据输入和计算机处理、存储 和数据检索；与集团主席和其他人合作 集团研究人员提高临床试验质量 通过改进的形式、更统一和可重复的数据定义， 以及更经济的数据流；帮助集团主席 集团的行政管理；分析并发布结果 与研究协调员一起研究；使用数据 收集这些信息是为了尝试寻找有关预后因素和晚期因素的新线索 影响；并对有效设计进行统计研究， 癌症临床试验和癌症控制的进行和分析 研究。