Addressing the Cancer Burden in South America and the US Hispanic and Native American Populations through Clinical Trials

通过临床试验解决南美洲以及美国西班牙裔和美洲原住民人口的癌症负担

• 批准号: 9759602
• 负责人: JOHN J CROWLEY
• 金额: $ 1.5万
• 依托单位: CANCER RESEARCH AND BIOSTATISTICS (CRAB)
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9759602
• 关键词: Address; Adolescent; Area; Cancer Burden; Chile; Clinical Oncology; Clinical Trials; Clinical Trials Design; Collaborations; Colombia; Country; Development; Future; Goals; Health; Health Professional; Hispanic Americans; Institutes; Institution; Latin America; Latin American; Lead; Malignant Neoplasms; Mexico; Mission; National Cancer Institute; National Clinical Trials Network; Native Americans; Output; Participant; Patients; Peru; Population; Prevention; Protocols documentation; Research; Research Personnel; Rest; South America; Southwest Oncology Group; System; Translating; Underrepresented Populations; Underserved Population; cancer clinical trial; cancer therapy; clinical infrastructure; collaborative trial; design; improved; innovation; insight; interest; novel; oncology; programs; research clinical testing; survivorship; symposium; symptom management; young adult

SUMMARY The purpose of this conference is to support a high quality scientific forum addressing the cancer burden in South America with the aim of generating studies to address that burden, with results that are potentially generalizable and applicable to the US Hispanic and Native American populations. This underserved population will be significantly represented by investigators from the host country, from the rest of South America, and from Mexico and the US. Experts in the design, conduct and analysis of clinical trials in oncology will join with healthcare professionals and institutional leaders to conduct a conference at a host country in South America, delivering a program that: (1) identifies the cancer burden in South America and explores what issues are unique to that continent, which generalize to the rest of Latin America, and which are also applicable to the US Hispanic and Native American population; (2) discusses the infrastructure for clinical trials in the region, the opportunities and challenges to collaborative trials with the US, and the current and possible future systems for multi‐ institution trials in the hemisphere; (3) shares ideas on innovative clinical trial design, conduct and analyses; (4) prioritizes possible collaborative projects and explores mechanisms for accomplishing those priorities; and (5) serves as a nidus for the development of actual clinical trials, the results of which should have important health implications for the hemisphere. Leaders of the National Cancer Institute in Chile have committed to support this conference. Three similar institutes (in Mexico, Peru and Colombia) have joined SWOG through the SWOG Latin American Initiative (SLAI) and have begun to collaborate with their US colleagues and counterparts, and Chile has recently expressed interest in joining SWOG. The goal of the research presented at the conference is to strengthen current collaborations and build novel initiatives in the areas of prevention, treatment and symptom management of common cancer problems in the region. We plan to uncover unique obstacles that limit oncology clinical trials and inspire novel solutions to overcome them, to fully understand the cancer burden in South America and how it relates to research programs in the US, and to help in the development of specific cancer clinical trials.

总结 本次会议的目的是支持一个高质量的科学论坛，讨论 南美的癌症负担，目的是进行研究以解决这一负担， 结果是潜在的普遍性和适用于美国西班牙裔和美国土著 人口。这些服务不足的人群将由调查人员代表 来自东道国，来自南美其他国家，来自墨西哥和美国。专家 肿瘤学临床试验的设计、实施和分析将与医疗保健相结合， 专家和机构领导人在南方的一个东道国举行会议， 美国，提供了一个计划，（1）确定在南美洲的癌症负担， 探讨了该大陆特有的问题，这些问题适用于拉丁美洲的其他地区， 这也适用于美国西班牙裔和美洲土著人口;（2）讨论 该地区临床试验的基础设施， 与美国的合作试验，以及当前和未来可能的多学科系统， （3）分享关于创新临床试验设计、开展 （4）确定可能的合作项目的优先次序，并探讨 完成这些优先事项;（5）作为实际临床发展的核心 试验，其结果应具有重要的健康影响， 半球智利国家癌症研究所的领导人承诺支持这一点。 会议三个类似的研究所（在墨西哥、秘鲁和哥伦比亚）通过以下方式加入了SWOG： SWOG拉丁美洲倡议（SLAI），并已开始与美国合作 智利最近表示有兴趣加入SWOG。的 在会议上提出的研究目标是加强目前的合作， 在预防、治疗和症状管理领域建立新的举措， 该地区常见的癌症问题。我们计划找出限制 肿瘤临床试验，并激发新的解决方案，以克服他们，充分了解 南美洲的癌症负担及其与美国研究项目的关系， 在特定癌症临床试验的发展中。