Addressing the Cancer Burden in South America and the US Hispanic and Native American Populations through Clinical Trials

通过临床试验解决南美洲以及美国西班牙裔和美洲原住民人口的癌症负担

• 批准号: 9759602
• 负责人: JOHN J CROWLEY
• 金额: $ 1.5万
• 依托单位: CANCER RESEARCH AND BIOSTATISTICS (CRAB)
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9759602
• 关键词: Address; Adolescent; Area; Cancer Burden; Chile; Clinical Oncology; Clinical Trials; Clinical Trials Design; Collaborations; Colombia; Country; Development; Future; Goals; Health; Health Professional; Hispanic Americans; Institutes; Institution; Latin America; Latin American; Lead; Malignant Neoplasms; Mexico; Mission; National Cancer Institute; National Clinical Trials Network; Native Americans; Output; Participant; Patients; Peru; Population; Prevention; Protocols documentation; Research; Research Personnel; Rest; South America; Southwest Oncology Group; System; Translating; Underrepresented Populations; Underserved Population; cancer clinical trial; cancer therapy; clinical infrastructure; collaborative trial; design; improved; innovation; insight; interest; novel; oncology; programs; research clinical testing; survivorship; symposium; symptom management; young adult

SUMMARY The purpose of this conference is to support a high quality scientific forum addressing the cancer burden in South America with the aim of generating studies to address that burden, with results that are potentially generalizable and applicable to the US Hispanic and Native American populations. This underserved population will be significantly represented by investigators from the host country, from the rest of South America, and from Mexico and the US. Experts in the design, conduct and analysis of clinical trials in oncology will join with healthcare professionals and institutional leaders to conduct a conference at a host country in South America, delivering a program that: (1) identifies the cancer burden in South America and explores what issues are unique to that continent, which generalize to the rest of Latin America, and which are also applicable to the US Hispanic and Native American population; (2) discusses the infrastructure for clinical trials in the region, the opportunities and challenges to collaborative trials with the US, and the current and possible future systems for multi‐ institution trials in the hemisphere; (3) shares ideas on innovative clinical trial design, conduct and analyses; (4) prioritizes possible collaborative projects and explores mechanisms for accomplishing those priorities; and (5) serves as a nidus for the development of actual clinical trials, the results of which should have important health implications for the hemisphere. Leaders of the National Cancer Institute in Chile have committed to support this conference. Three similar institutes (in Mexico, Peru and Colombia) have joined SWOG through the SWOG Latin American Initiative (SLAI) and have begun to collaborate with their US colleagues and counterparts, and Chile has recently expressed interest in joining SWOG. The goal of the research presented at the conference is to strengthen current collaborations and build novel initiatives in the areas of prevention, treatment and symptom management of common cancer problems in the region. We plan to uncover unique obstacles that limit oncology clinical trials and inspire novel solutions to overcome them, to fully understand the cancer burden in South America and how it relates to research programs in the US, and to help in the development of specific cancer clinical trials.

概括 本次会议的目的是支持一个高质量的科学论坛，解决以下问题 南美洲的癌症负担，旨在开展研究来解决这一负担， 结果可能具有普遍性并适用于美国西班牙裔和美洲原住民 人口。调查人员将显着代表这一服务不足的人群 来自东道国、南美其他地区、墨西哥和美国。专家 肿瘤学临床试验的设计、实施和分析将与医疗保健结合起来 专业人士和机构领导人在南方东道国召开会议 美国，实施一项计划：(1) 确定南美洲的癌症负担和 探讨该大陆独有的问题，这些问题普遍适用于拉丁美洲其他地区， 并且也适用于美国西班牙裔和美洲原住民人口； (2)讨论 该地区临床试验的基础设施、机遇和挑战 与美国的合作试验，以及当前和未来可能的多系统 西半球的机构试验； (3) 分享创新临床试验设计、实施的想法 和分析； （四）优先考虑可能的合作项目并探索合作机制 完成这些优先事项； (5)作为实际临床开发的基础 试验，其结果应该对健康产生重要影响 半球。智利国家癌症研究所的领导承诺支持这一项目 会议。三个类似的机构（位于墨西哥、秘鲁和哥伦比亚）已通过以下方式加入 SWOG： SWOG 拉丁美洲倡议 (SLAI) 并已开始与美国合作 同事和同行，智利最近表示有兴趣加入 SWOG。这 会议上提出的研究的目标是加强当前的合作和 在预防、治疗和症状管理领域制定新举措 该地区常见的癌症问题。我们计划发现限制的独特障碍 肿瘤学临床试验并激发新的解决方案来克服它们，充分了解 南美洲的癌症负担及其与美国研究项目的关系，并帮助 开发特定癌症临床试验。