SOUTHWEST ONCOLOGY GROUP STATISTICAL CENTER

描述（由申请人提供）：西南肿瘤组（SWOG）的使命是进行临床试验，以预防和治疗成人癌症，并提高癌症幸存者的生活质量。这一使命是通过集团主席办公室、运营办公室、统计中心和集团各机构专门的肿瘤学专业人员的共同努力完成的。统计中心通过以下关键活动为集团的使命做出贡献：1）参与方案制定，强调统计学上合理的研究设计; 2）收集、审查、管理和存储集团研究数据，并遵循合理的质量控制程序，确保数据评价的完整性; 3）开发和维护电子应用程序，以支持西南肿瘤组的研究和目标，包括数据收集，数据管理，数据检索和分析; 5）进行方法学研究，以解决对癌症临床试验的进行和辅助生物学研究重要的正在进行的设计和分析问题; 6）参与新的临床研究助理（CRA）和本集团年轻研究者的培训。生物统计学家和数据协调员在统计分析，研究设计和利用最先进的科学和数据管理策略方面教育研究者，护士肿瘤学家和CRA;和7）与小组主席和小组其他研究者合作，通过使用改进的数据收集表格、可重复的数据定义和经济的数据流来提高临床试验的质量，有效利用统计中心的资源。

DESCRIPTION (Provided by applicant): The mission of the Southwest Oncology Group (SWOG) is to conduct clinical trials to prevent and treat cancer in adults, and to improve the quality of life for cancer survivors. The mission is accomplished through the mutual efforts ofthe Group Chair's Office, the Operations Office, the Statistical Center and the dedicated oncology professionals in the institutions of the Group. The Statistical Center contributes to the mission of the Group though the following key activities: 1) Participation in protocol development, emphasizing statistically sound study designs; 2) Collection, review, manage and store data from Group studies, and to follow sound quality control procedures which ensure the integrity of data evaluations; 3) Development and maintenance of electronic applications to support the research and goals of the Southwest Oncology Group, including data collection, data management, data retrieval and analysis; 4) Analysis, interpretation and publication of results from ail Southwest Oncology Group studies; 5) Performance of methodologic research to address ongoing design and analysis issues important to the conduct of cancer clinical trials and to ancillary biologic studies; 6) Participation in training of new Clinical Research Associates (CRAs) and of Young Investigators in the Group. Biostatisticians and Data Coordinators educate investigators, nurse oncologists and CRAs in statistical analysis, research design and the utilization of the most advanced scientific and data management strategies; and 7) Collaboration with the Group Chair and other investigators in the Group to improve the quality of clinical trials through the use of improved data collection forms, reproducible data definitions and economical data flow, and efficient use of Statistical Center resources.