SOUTHWEST ONCOLOGY GROUP STATISTICAL CENTER

描述(申请人提供)：西南肿瘤学小组(SWOG)的使命是进行预防和治疗成人癌症的临床试验，并提高癌症幸存者的生活质量。这项任务是通过小组主席办公室、业务办公室、统计中心和小组各机构中敬业的肿瘤学专业人员的共同努力完成的。统计中心通过以下主要活动为该小组的使命作出贡献：1)参与制定方案，强调统计上可靠的研究设计；2)收集、审查、管理和存储来自小组研究的数据，并遵循确保数据评估完整性的健全质量控制程序；3)开发和维护电子应用程序，以支持西南肿瘤小组的研究和目标，包括数据收集、数据管理、数据检索和分析；4)分析、解释和出版所有西南肿瘤小组研究的结果；5)开展方法学研究，以解决对进行癌症临床试验和辅助生物学研究非常重要的持续设计和分析问题；6)参与培训新的临床研究助理(CRA)和集团中的青年研究人员。生物统计师和数据协调员在统计分析、研究设计和使用最先进的科学和数据管理策略方面对研究人员、护士肿瘤学家和CRA进行培训；以及7)与集团主席和集团其他调查人员合作，通过使用改进的数据收集形式、可重复的数据定义和经济的数据流以及有效利用统计中心资源来提高临床试验的质量。

DESCRIPTION (Provided by applicant): The mission of the Southwest Oncology Group (SWOG) is to conduct clinical trials to prevent and treat cancer in adults, and to improve the quality of life for cancer survivors. The mission is accomplished through the mutual efforts ofthe Group Chair's Office, the Operations Office, the Statistical Center and the dedicated oncology professionals in the institutions of the Group. The Statistical Center contributes to the mission of the Group though the following key activities: 1) Participation in protocol development, emphasizing statistically sound study designs; 2) Collection, review, manage and store data from Group studies, and to follow sound quality control procedures which ensure the integrity of data evaluations; 3) Development and maintenance of electronic applications to support the research and goals of the Southwest Oncology Group, including data collection, data management, data retrieval and analysis; 4) Analysis, interpretation and publication of results from ail Southwest Oncology Group studies; 5) Performance of methodologic research to address ongoing design and analysis issues important to the conduct of cancer clinical trials and to ancillary biologic studies; 6) Participation in training of new Clinical Research Associates (CRAs) and of Young Investigators in the Group. Biostatisticians and Data Coordinators educate investigators, nurse oncologists and CRAs in statistical analysis, research design and the utilization of the most advanced scientific and data management strategies; and 7) Collaboration with the Group Chair and other investigators in the Group to improve the quality of clinical trials through the use of improved data collection forms, reproducible data definitions and economical data flow, and efficient use of Statistical Center resources.