SOUTHWEST ONCOLOGY GROUP STAISTICAL CENTER

西南肿瘤集团统计中心

• 批准号: 3558234
• 负责人: JOHN J CROWLEY
• 金额: $ 112.89万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-01-01 至 1987-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3558234
• 关键词: cooperative study; human subject; neoplasm /cancer epidemiology; online computer

This proposal describes how the Southwest Oncology Group Statistical Center would be organized and operated to provide data management and evaluation, statistical analysis, and input on design of protocols for clinical trials in cancer. It is proposed to locate the Statistical Center at the Fred Hutchinson Cancer Research Center in Seattle, Washington, under the direction of Dr. John Crowley, with Dr. Brent Blumenstein as Deputy Director. The application concentrates on the role of the Statistical Center in developing and monitoring protocols, including eligibility criteria, registration and randomization procedures, endpoint and sample size determination, trial monitoring, and analysis strategies. Data management and database management strategies are described in detail. Transition plans and plans for the future are also discussed.

本提案描述了西南肿瘤学组统计中心如何 将组织和运作，以提供数据管理和评估， 统计分析和临床试验方案设计的输入 在癌症中。 建议将统计中心设在弗雷德 位于华盛顿西雅图的哈钦森癌症研究中心， 由约翰·克劳利博士指导，布伦特·布卢门斯坦博士担任副主席 导演 该应用程序集中在统计的作用 制定和监测方案的中心，包括资格 标准、注册和随机化程序、终点和样本 规模确定、试验监测和分析策略。 数据 管理和数据库管理策略进行了详细描述。 还讨论了过渡计划和未来计划。