MOLECULAR BIOLOGY OF GASTRIC MUCOSAL CELLS

胃粘膜细胞的分子生物学

• 批准号: 5216183
• 负责人: Tadataka Yamada
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5216183
• 关键词: gastric mucosa; gene expression; hormone receptor; molecular cloning; peptide hormone; protein structure function

The purpose of this project is to characterize the molecular biology of peptide hormones and the receptors that they recognize. The genes encoding the hormones and the receptors are cloned and their structures elucidated. The mechanisms by which the hormones are post-translationally modified are examined by expressing their genes with specific mutations at important processing sites in heterologous cells. The functional elements of the receptor are characterized.

该项目的目的是描述 肽激素和它们识别的受体。 的基因 编码激素和受体的基因被克隆， 阐明。 激素的作用机制 通过表达它们的基因来检查后修饰的， 异源细胞中重要加工位点的特异性突变。 该受体的功能元件的特点。