EXERCISE EFFECT ON FUNCTION OF RESIDENTS WITH AD

运动对 AD 居民功能的影响

• 批准号: 2035976
• 负责人: Ruth M Tappen
• 金额: $ 16.71万
• 依托单位: FLORIDA ATLANTIC UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2035976
• 关键词: Alzheimer's disease; balance; behavioral /social science research tag; clinical research; exercise; functional ability; gait; health care cost /financing; health services research tag; human subject; human therapy evaluation; muscle strength; nursing homes; psychomotor function; self care; statistics /biometry

Given the growing number of nursing home residents with Alzheimer's diseases, cost effective interventions that can reduce or delay their need for assistance with mobility and self-care activities of daily living are sorely needed. There is increasing evidence that exercise may represent such an intervention. The purpose of this study is to compare the effectiveness of 1) a comprehensive exercise program to build strength, flexibility, balance and endurance that is specifically designed for this population 2) a more commonly used supervised walking program and 3) attention control in a 3 group repeated measures experimental design with random selection and random assignment to treatment. One hundred twenty deconditioned resignets with a confirmed diagnosis of Alzheimer's disease will be selected fromt he impatient units of three nursing homes. Residents entered into the study will received treatment 5 times a week for 16 weeks. Data on their physical performance and the degree of assistance they require in mobility-related and self-care ADL's will be collected at pretest and post-test. Multivariate and univeriate repeated measures analysis of variance will be used to determine the impact of the intervention. It is hypothesized that the deconditioned nursing home residents with Alzheimer's disease who participate in the comprehensive exercise program will demonstrate greater improvement in physical performance, mobility-related activities of daily living (ADL's) and self-care ADL's than those in the walking group who, in turn, will demonstrate greater improvement than those in the attention control. A low cost intervention such as the one proposed that reduces excess disability and maintains residents at their highest possible level of function would not only increase their quality of life but also reduce the cost of their care.

鉴于越来越多的养老院居民， 阿尔茨海默病，成本效益的干预措施，可以减少 或延迟他们在行动和自我照顾方面的援助需求 非常需要日常生活活动。 人们日益 有证据表明，运动可能代表这种干预。 本研究的目的是比较1）a 全面的锻炼计划，以建立力量，灵活性， 专门为此设计的平衡和耐力 人口2）更常用的监督步行计划 3）注意控制在3组重复测量中的作用 随机选择随机分配试验设计 接受治疗 一百二十名解除限制的辞职者，并获得 确诊阿尔茨海默病的患者将从 他不耐烦的单位三个养老院。 居民进入 研究将接受每周5次的治疗，持续16周。 关于他们的身体状况和援助程度的数据 他们需要在移动相关和自我护理ADL的将是 在测试前和测试后收集。 多变量和单变量重复测量方差分析 将用于确定干预的影响。 是 假设那些没有条件的养老院居民 老年痴呆症患者参加综合锻炼 该计划将证明在物理上有更大的改善 日常生活活动能力（ADL）， 自我照顾ADL的比那些在步行组，反过来，将 表现出更大的改善比那些在注意 控制 一个低成本的干预措施，如一个建议， 减少过度残疾并使居民保持最高水平 可能的功能水平不仅会提高他们的质量， 生活，同时也降低了他们的护理成本。