EXERCISE EFFECT ON FUNCTION OF RESIDENTS WITH AD

运动对 AD 居民功能的影响

• 批准号: 2702922
• 负责人: Ruth M Tappen
• 金额: $ 16.5万
• 依托单位: FLORIDA ATLANTIC UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2702922
• 关键词: Alzheimer's disease; balance; behavioral /social science research tag; clinical research; exercise; functional ability; gait; health care cost /financing; health services research tag; human subject; human therapy evaluation; muscle strength; nursing homes; psychomotor function; self care; statistics /biometry

Given the growing number of nursing home residents with Alzheimer's diseases, cost effective interventions that can reduce or delay their need for assistance with mobility and self-care activities of daily living are sorely needed. There is increasing evidence that exercise may represent such an intervention. The purpose of this study is to compare the effectiveness of 1) a comprehensive exercise program to build strength, flexibility, balance and endurance that is specifically designed for this population 2) a more commonly used supervised walking program and 3) attention control in a 3 group repeated measures experimental design with random selection and random assignment to treatment. One hundred twenty deconditioned resignets with a confirmed diagnosis of Alzheimer's disease will be selected fromt he impatient units of three nursing homes. Residents entered into the study will received treatment 5 times a week for 16 weeks. Data on their physical performance and the degree of assistance they require in mobility-related and self-care ADL's will be collected at pretest and post-test. Multivariate and univeriate repeated measures analysis of variance will be used to determine the impact of the intervention. It is hypothesized that the deconditioned nursing home residents with Alzheimer's disease who participate in the comprehensive exercise program will demonstrate greater improvement in physical performance, mobility-related activities of daily living (ADL's) and self-care ADL's than those in the walking group who, in turn, will demonstrate greater improvement than those in the attention control. A low cost intervention such as the one proposed that reduces excess disability and maintains residents at their highest possible level of function would not only increase their quality of life but also reduce the cost of their care.

鉴于越来越多的疗养院居民 阿尔茨海默病，具有成本效益的干预措施可以减少 或延迟他们对行动和自我护理方面的帮助的需求 日常生活活动是非常需要的。 有越来越多 有证据表明运动可能代表这种干预措施。 本研究的目的是比较 1)a 的有效性 全面的锻炼计划，以增强力量、灵活性、 专为此设计的平衡性和耐力 人口2）更常用的监督步行程序 3) 3组重复测量中的注意力控制 随机选择和随机分配的实验设计 来治疗。 一百二十张破损的签名，上面有 确诊阿尔茨海默病将从中选择 他不耐烦的单位是三个疗养院。 居民进入 该研究将每周接受 5 次治疗，持续 16 周。 有关其身体表现和协助程度的数据 他们在行动相关和自我护理方面的 ADL 要求将是 在测试前和测试后收集。 多变量和单变量重复测量方差分析 将用于确定干预措施的影响。 这是 假设条件恶劣的疗养院居民 老年痴呆症患者参加综合运动 计划将显示出身体方面的更大改善 表现、与行动相关的日常生活活动 (ADL) 以及 自我护理 ADL 高于步行组的人，反过来，步行组的人会 表现出比关注的人有更大的进步 控制。 一种低成本的干预措施，例如提出的干预措施 减少过度残疾并使居民保持最佳状态 可能的功能水平不仅会提高他们的质量 生活的同时也减少了他们的护理费用。